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公开(公告)号：US11952423B2
公开(公告)日：2024-04-09
申请号：US18318610
申请日：2023-05-16
发明人： Hiroshi Shiku , Yasushi Akahori , Kento Tanaka , Ayaka Yatsu , Junya Ichikawa , Toshiaki Ohtsuka , Shiho Kozuma , Ryuji Hashimoto , Makiko Nakayama , Naoya Shinozaki , Kensuke Nakamura , Ichiro Watanabe , Shinji Furuzono
CPC分类号： C07K16/2809 , C07K16/32 , C07K2317/31 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/53 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622
摘要： A novel antibody that can be used as an anti-tumor agent and an anti-tumor agent that comprises, as an active ingredient, a molecule containing such an antibody.
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公开(公告)号：US09751944B2
公开(公告)日：2017-09-05
申请号：US14731519
申请日：2015-06-05
IPC分类号： A61K39/00 , A61K39/395 , C07K16/28 , A61K45/06
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/545 , C07K2317/24 , C07K2317/30 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2319/30
摘要： Provided is a pharmaceutical composition for treating and/or preventing abnormal bone metabolism targeting a protein encoded by a gene strongly expressed in osteoclasts. Specifically provided is a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation, and the like.
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公开(公告)号：US20150299318A1
公开(公告)日：2015-10-22
申请号：US14731519
申请日：2015-06-05
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/545 , C07K2317/24 , C07K2317/30 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2319/30
摘要： Provided is a pharmaceutical composition for treating and/or preventing abnormal bone metabolism targeting a protein encoded by a gene strongly expressed in osteoclasts. Specifically provided is a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation, and the like.
摘要翻译： 本发明提供一种用于治疗和/或预防由破骨细胞强烈表达的基因编码的蛋白质的异常骨代谢的药物组合物。 具体提供含有特异性识别人Siglec-15并具有抑制破骨细胞形成活性的抗体的药物组合物等。
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公开(公告)号：US09079959B2
公开(公告)日：2015-07-14
申请号：US14041479
申请日：2013-09-30
IPC分类号： A61K39/00 , A61K39/395 , C07K16/28
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/545 , C07K2317/24 , C07K2317/30 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2319/30
摘要： Provided is a pharmaceutical composition for treating and/or preventing abnormal bone metabolism targeting a protein encoded by a gene strongly expressed in osteoclasts. Specifically provided is a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation, and the like.
摘要翻译： 本发明提供一种用于治疗和/或预防由破骨细胞强烈表达的基因编码的蛋白质的异常骨代谢的药物组合物。 具体提供含有特异性识别人Siglec-15并具有抑制破骨细胞形成活性的抗体的药物组合物等。
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公开(公告)号：US20140065146A1
公开(公告)日：2014-03-06
申请号：US14041479
申请日：2013-09-30
IPC分类号： C07K16/28
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/545 , C07K2317/24 , C07K2317/30 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2319/30
摘要： Provided is a pharmaceutical composition for treating and/or preventing abnormal bone metabolism targeting a protein encoded by a gene strongly expressed in osteoclasts. Specifically provided is a pharmaceutical composition containing an antibody which specifically recognizes human Siglec-15 and has an activity of inhibiting osteoclast formation, and the like.
摘要翻译： 本发明提供一种用于治疗和/或预防由破骨细胞强烈表达的基因编码的蛋白质的异常骨代谢的药物组合物。 具体提供含有特异性识别人Siglec-15并具有抑制破骨细胞形成活性的抗体的药物组合物等。
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