公开(公告)号：US11952423B2

公开(公告)日：2024-04-09

申请号：US18318610

申请日：2023-05-16

申请人： MIE UNIVERSITY ,  DAIICHI SANKYO COMPANY, LIMITED

发明人： Hiroshi Shiku ,  Yasushi Akahori ,  Kento Tanaka ,  Ayaka Yatsu ,  Junya Ichikawa ,  Toshiaki Ohtsuka ,  Shiho Kozuma ,  Ryuji Hashimoto ,  Makiko Nakayama ,  Naoya Shinozaki ,  Kensuke Nakamura ,  Ichiro Watanabe ,  Shinji Furuzono

IPC分类号： C07K16/28 ,  C07K16/32

CPC分类号： C07K16/2809 ,  C07K16/32 ,  C07K2317/31 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/528 ,  C07K2317/53 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622

摘要： A novel antibody that can be used as an anti-tumor agent and an anti-tumor agent that comprises, as an active ingredient, a molecule containing such an antibody.

公开(公告)号：US09708382B2

公开(公告)日：2017-07-18

申请号：US13956916

申请日：2013-08-01

申请人： Daiichi Sankyo Company, Limited

发明人： Tohru Takahashi ,  Naoya Shinozaki ,  Takeshi Takizawa ,  Takako Kimura

IPC分类号： C40B40/10 ,  C07K14/715 ,  C07K14/525 ,  C40B40/02

CPC分类号： C07K14/525 ,  C07K14/7151 ,  C40B40/02 ,  C40B40/10

摘要： The present invention provides a peptide library comprising a plurality of mutant peptides based on the extracellular binding domain of the TACI protein. The mutant peptides of the library have the capacity to bind to target molecules other than the endogenous TACI ligands. The present invention further provides a peptide library comprising a plurality of mutant peptides each comprising an amino acid sequence of SEQ ID NO: 1 in the Sequence Listing.