公开(公告)号：US10155721B2

公开(公告)日：2018-12-18

申请号：US15495949

申请日：2017-04-24

Applicant: Macau University of Science and Technology

Inventor： Guo-Yuan Zhu ,  Zhi-Hong Jiang ,  Ji Yang ,  Xiao-Jun Yao ,  Xin Liu ,  Jing Fu ,  Li-Ping Bai ,  Liang Liu

IPC: C07C237/26 ,  C07C231/24

Abstract: One example embodiment is a lignanamide that includes a benzo-angular triquinane skeleton. The lignanamide is represented by formula (I) and any derivative of the formula (I), in which R is represented by —OH or —OCH3. Another example embodiment relates to a method of treating neurodegenerative disease by administering the lignanamide of the formula (I) to a person in need thereof.