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    Chemically based vascular occlusion device deployment
    1.
    发明申请
    Chemically based vascular occlusion device deployment 失效
    化学基础的血管闭塞装置部署

    公开(公告)号：US20070239192A1

    公开(公告)日：2007-10-11

    申请号：US11394876

    申请日：2006-03-31

    申请人： Marc Litzenberg ,  Donald Jones ,  Vladimir Mitelberg

    发明人： Marc Litzenberg ,  Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/1214 ,  A61B2017/00473 ,  A61B2017/1205 ,  A61B2017/12068 ,  A61B2017/12072 ,  A61B2017/12081

    摘要： A vascular occlusion device deployment system for placing an occlusion device at a preselected site within the vasculature of a patient. The deployment system employing a pusher having a lumen with an opening at the distal end of the pusher. A vascular occlusion device is connected to the distal end of the pusher by a portion that is removeably disposed within the opening. The portion of the occlusion device is forced out of the opening by an expandable reaction chamber, thereby deploying the occlusion device. The expandable reaction chamber, prior to deployment, has multiple chambers separated by a heat-dissolvable membrane. When the membrane is dissolved, components from the chambers react and expand, leading to deployment.

    摘要翻译： 一种血管闭塞装置展开系统，用于将闭塞装置放置在患者脉管系统内的预选部位。 采用具有在推动器的远端具有开口的内腔的推动器的展开系统。 血管闭塞装置通过可移除地设置在开口内的部分连接到推动器的远端。 闭塞装置的部分被可膨胀的反应室从开口压出，从而展开闭塞装置。 在展开之前，可膨胀反应室具有由热可溶性隔膜隔开的多个室。 当膜溶解时，来自室的组分反应并膨胀，导致部署。

    Stretch resistant embolic coil delivery system with mechanical release mechanism
    3.
    发明申请
    Stretch resistant embolic coil delivery system with mechanical release mechanism 审中-公开
    具有机械释放机制的抗拉伸栓塞线圈输送系统

    公开(公告)号：US20060276827A1

    公开(公告)日：2006-12-07

    申请号：US11172198

    申请日：2005-06-30

    申请人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

    发明人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1215 ,  A61B17/12154 ,  A61B2017/00292 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12054 ,  A61M25/00

    摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is slidably disposed within the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the engagement member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.

    摘要翻译： 一种用于将栓塞装置放置在身体的容器内的预定位置处的医疗装置，包括输送导管和具有通过其的腔的柔性推动器构件，并且可滑动地设置在导管的腔内。 弹性阻塞栓塞装置通过机械互锁机构保持在输送导管内，该联动机构包括可滑动地设置在推动器构件内并且延伸穿过栓塞装置的近端处的保持环的接合构件。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定在接合构件上。 接合构件接合栓塞装置上的保持环。 当栓塞装置前进到血管内的预定位置时，分离构件从孔中取出，从而在治疗部位释放栓塞装置。

    Occluding vasculature of a patient using embolic coil with improved platelet adhesion
    6.
    发明申请
    Occluding vasculature of a patient using embolic coil with improved platelet adhesion 审中-公开
    阻塞患者的脉管系统使用具有改善的血小板粘附的栓塞线圈

    公开(公告)号：US20050240216A1

    公开(公告)日：2005-10-27

    申请号：US11168172

    申请日：2005-06-28

    申请人： Donald Jones ,  Vladimir Mitelberg

    发明人： Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61B17/00 ,  A61B17/12 ,  A61F2/00 ,  A61L31/02 ,  A61L31/14 ,  A61M29/00

    CPC分类号： A61L31/14 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61F2/0077 ,  A61L31/022 ,  A61L2430/36

    摘要： A method as provided for occluding the vasculature of a patient. The method comprises the steps of providing a plurality of embolic coils having a textured surface. The embolic coils are introduced into the patient's vasculature. In this manner, the textured surface provides improved platelet adhesion compared to a non-textured surface, to promote clotting. In the illustrative embodiment, the embolic coil comprises a platinum-tungsten alloy wire and the texturing is performed by abrasion or sandblasting to provide substantially uniform roughness comprising pockets having diameters of about 0.125 microns to about fifty microns and depths of about 0.25 microns to about twenty microns.

    摘要翻译： 提供用于阻塞患者脉管系统的方法。 该方法包括提供具有纹理表面的多个栓塞线圈的步骤。 栓塞线圈被引入患者的脉管系统。 以这种方式，纹理表面与无纹理表面相比提供改善的血小板粘附，以促进凝血。 在说明性实施例中，栓塞线圈包括铂 - 钨合金线，并且通过磨损或喷砂进行纹理化，以提供基本上均匀的粗糙度，其包括直径为约0.125微米至约50微米且深度为约0.25微米至约20 微米。

    Self-expanding stent and stent delivery system with distal protection
    7.
    发明申请
    Self-expanding stent and stent delivery system with distal protection 审中-公开
    自扩张支架和支架输送系统具有远端保护

    公开(公告)号：US20050049669A1

    公开(公告)日：2005-03-03

    申请号：US10651605

    申请日：2003-08-29

    申请人： Donald Jones ,  Vladimir Mitelberg

    发明人： Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61F2/82 ,  A61F2/01 ,  A61F2/06 ,  A61F2/84

    CPC分类号： A61F2/013 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/018 ,  A61F2002/9665 ,  A61F2230/0008 ,  A61F2230/0067

    摘要： A self-expanding stent and stent delivery system are provided for treating vascular diseases such as partially occluded blood vessels within the brain. The self-expanding stent is preferably mounted on an elongated core wire including proximal, intermediate and distal cylindrical members disposed about the core wire. The proximal, intermediate, and distal cylindrical members are spaced apart such that first and second gaps are formed. The stent, which includes anchor members, is mounted on the intermediate cylindrical member such that the anchor members interlock within the gaps between the cylindrical members. The self-expanding stent and elongated core wire are disposed within a delivery lumen of a balloon catheter such that the balloon catheter compresses and constrains the stent about the intermediate cylindrical member to thereby interlock the stent onto the core wire. The elongated core wire further includes an expandable capture basket attached to the distal end of the elongated core wire in order to capture embolic debris released during the angioplasty of the blood vessel and the deployment of the self-expanding stent.

    摘要翻译： 提供自扩张支架和支架输送系统用于治疗血管疾病如脑内的部分闭塞的血管。 自扩张支架优选地安装在细长的芯线上，其包括围绕芯线设置的近端，中间和远端圆柱形构件。 近端，中间和远端圆柱形构件间隔开，使得形成第一和第二间隙。 包括锚固构件的支架安装在中间圆柱形构件上，使得锚定构件在圆柱形构件之间的间隙内互锁。 自扩张支架和细长芯线设置在气囊导管的输送腔内，使得气囊导管压缩并约束支架围绕中间圆柱形构件，从而将支架联锁到芯线上。 细长芯线还包括连接到细长芯线的远端的可扩张捕获篮，以便捕获在血管成形术期间释放的栓塞碎屑和展开自扩张支架。

    Stent embolization device
    8.
    发明申请
    Stent embolization device 有权
    支架栓塞装置

    公开(公告)号：US20050033408A1

    公开(公告)日：2005-02-10

    申请号：US10875843

    申请日：2004-06-23

    申请人： Donald Jones ,  Vladimir Mitelberg

    发明人： Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61B17/00 ,  A61B17/12 ,  A61F2/06 ,  A61F2/84

    CPC分类号： A61B17/12022 ,  A61B17/12118 ,  A61B17/12172 ,  A61B2017/12081

    摘要： A method and device used for treating an aneurysm or a vessel of a patient. An embolization element that is adapted to reduce or block the blood flow into the aneurysm or vessel, together with a stent connected to the embolization element, is provided. The embolization element includes an expandible member. The embolization element and the stent are introduced into the vessel leading to and communicating with the aneurysm or vessel. The embolization element is directed into the aneurysm or vessel, with the stent being located in another vessel communicating with the first vessel. In this manner, the stent becomes compressed against the inner wall of the second vessel for anchoring the embolization element. In one form of the invention, the stent comprises a helical coil and the embolization element comprises a collapsible framework.

    摘要翻译： 用于治疗患者的动脉瘤或血管的方法和装置。 提供了一种栓塞元件，其适于减少或阻塞进入动脉瘤或血管的血流以及与栓塞元件连接的支架。 栓塞元件包括可膨胀构件。 将栓塞元件和支架引入导管并与动脉瘤或血管连通的血管。 栓塞元件被引导到动脉瘤或血管中，支架位于与第一血管连通的另一容器中。 以这种方式，支架相对于第二容器的内壁压缩以锚定栓塞元件。 在本发明的一种形式中，支架包括螺旋线圈，并且栓塞元件包括可折叠框架。

    Stent aneurysm embolization device
    9.
    发明申请
    Stent aneurysm embolization device 有权
    支架动脉瘤栓塞装置

    公开(公告)号：US20050033349A1

    公开(公告)日：2005-02-10

    申请号：US10874954

    申请日：2004-06-23

    申请人： Donald Jones ,  Vladimir Mitelberg

    发明人： Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61B17/12 ,  A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/12118 ,  A61B17/12145 ,  A61B17/12172 ,  A61B2017/1205

    摘要： A method and device used for treating an aneurysm of a patient. A framework for supporting one or more embolization elements is introduced into the patient's aneurysm. A stent, connected to the framework is introduced into a vessel leading into and communicating with the aneurysm, with the stent being compressed against the inner wall of the vessel for anchoring the framework. One or more embolization elements are introduced through the framework into the aneurysm, and in this manner the framework maintains the one or more embolization elements within the aneurysm. In the illustrative embodiment, the embolization element comprises an embolic coil, the stent comprises a helical coil, and the framework and helical coil are connected so as to be introduced into the patient simultaneously.

    摘要翻译： 用于治疗患者动脉瘤的方法和装置。 支持一个或多个栓塞元件的框架被引入患者的动脉瘤。 连接到框架的支架被引入到导管和与动脉瘤连通的容器中，支架被压靠在容器的内壁上以锚固框架。 通过框架将一个或多个栓塞元件引入动脉瘤，并且以这种方式，框架维持动脉瘤内的一个或多个栓塞元件。 在说明性实施例中，栓塞元件包括栓塞线圈，支架包括螺旋线圈，框架和螺旋线圈​​连接以同时引入患者。

    HEATED VASCULAR OCCLUSION COIL DEPLOYMENT SYSTEM
    10.
    发明申请
    HEATED VASCULAR OCCLUSION COIL DEPLOYMENT SYSTEM 有权
    加热血管收缩系统

    公开(公告)号：US20070106323A1

    公开(公告)日：2007-05-10

    申请号：US11615243

    申请日：2006-12-22

    申请人： David Barry ,  Donald Jones ,  Vladimir Mitelberg

    发明人： David Barry ,  Donald Jones ,  Vladimir Mitelberg

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12022 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/12063 ,  A61B2017/12068

    摘要： An embolic coil deployment system for placing a coil at a preselected site within a vessel of the human body. The deployment system includes a heating element at the distal end of a delivery member and a heat responsive coupling for holding the coil during positioning of the coil and activation means for releasing the coil at a desired position within the vessel.

    摘要翻译： 一种用于将线圈放置在人体血管内的预选位置的栓塞线圈展开系统。 展开系统包括在输送构件的远端处的加热元件和用于在线圈定位期间保持线圈的热响应耦合件和用于将线圈释放在容器内的期望位置的激活装置。