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106 条记录 (耗时 0.019 秒)

    Indolecarboxylic compounds and their use as pharmaceutical compounds
    1.
    发明授权
    Indolecarboxylic compounds and their use as pharmaceutical compounds 失效
    吲哚羧化合物及其作为药物化合物的用途

    公开(公告)号：US06448285B1

    公开(公告)日：2002-09-10

    申请号：US09297636

    申请日：1999-07-26

    申请人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    发明人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    IPC分类号： A61K31405

    CPC分类号： A61Q19/00 ,  A61K8/492 ,  A61Q7/00 ,  C07D209/42 ,  C07D209/60

    摘要： The invention relates to the use, as active principle, in a physiologically acceptable medium, in a composition, of an effective amount of at least one compound of the indolecarboxylic family, this compound or these compositions being intended to treat disorders associated with overactivity of 5&agr;-reductase. These compounds or the compositions containing them are more particularly intended to treat androgen-dependent disorders such as seborrhoea and/or acne and/or hirsutism and/or androgenic alopecia. The invention also relates to novel compounds of the indolecarboxylic family and to compositions containing them.

    摘要翻译： 本发明涉及作为活性成分在生物学上可接受的介质中，在组合物中使用有效量的至少一种吲哚类羧酸化合物的化合物，该化合物或这些组合物旨在治疗与5α过度活性相关的疾病 - 还原酶。 这些化合物或含有它们的组合物更特别地用于治疗雄激素依赖性疾病如脂溢和/或痤疮和/或多毛症和/或雄激素性脱发。 本发明还涉及吲哚羧酸系的新化合物和含有它们的组合物。

    Compounds of the indolecarboxylic family and use thereof
    2.
    发明授权
    Compounds of the indolecarboxylic family and use thereof 失效
    吲哚羧酸家族的化合物及其用途

    公开(公告)号：US06596753B2

    公开(公告)日：2003-07-22

    申请号：US10176674

    申请日：2002-06-24

    申请人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    发明人： Bruno Bernard ,  Catherine Gerst ,  Jean-Baptiste Galey ,  Maria Dalko ,  Patrick Pichaud

    IPC分类号： A61K31405

    CPC分类号： A61Q19/00 ,  A61K8/492 ,  A61Q7/00 ,  C07D209/42 ,  C07D209/60

    摘要： The invention relates to the use, as active principle, in a physiologically acceptable medium, in a composition, of an effective amount of at least one compound of the indolecarboxylic family, this compound or these compositions being intended to treat disorders associated with overactivity of 5&agr;-reductase. These compounds or the compositions containing them are more particularly intended to treat androgen-dependent disorders such as, for example, seborrhoea and/or acne and/or hirsutism and/or androgenic alopecia. The invention also relates to novel compounds of the indolecarboxylic family and to compositions-containing them.

    摘要翻译： 本发明涉及作为活性成分在生物学上可接受的介质中，在组合物中使用有效量的至少一种吲哚类羧酸化合物的化合物，该化合物或这些组合物旨在治疗与5α过度活性相关的疾病 - 还原酶。 这些化合物或含有它们的组合物更特别地旨在治疗雄激素依赖性疾病，例如，脂溢和/或痤疮和/或多毛症和/或雄激素性脱发。 本发明还涉及吲哚羧酸家族的新化合物和含有它们的组合物。

    Salicylic acid derivatives and their use in cosmetic or dermatological compositions
    7.
    发明授权
    Salicylic acid derivatives and their use in cosmetic or dermatological compositions 失效
    水杨酸衍生物及其在化妆品或皮肤病学组合物中的用途

    公开(公告)号：US06255297B1

    公开(公告)日：2001-07-03

    申请号：US09367307

    申请日：1999-10-26

    申请人： Maria Dalko ,  Jean-Baptiste Galey

    发明人： Maria Dalko ,  Jean-Baptiste Galey

    IPC分类号： A61K3160

    CPC分类号： A61K8/37 ,  A61Q19/00 ,  A61Q19/08 ,  C07H15/203

    摘要： The invention relates to novel salicylic acid derivatives and to the use thereof in a cosmetic and/or dermatological composition intended for skincare, in particular to combat the signs of ageing of the skin and/or to improve the radiance of the complexion and/or to smooth out facial and/or body skin and/or to treat wrinkles and fine lines on the skin and/or to stimulate the process of epidermal renewal.

    摘要翻译： 本发明涉及新的水杨酸衍生物及其在用于护肤的化妆品和/或皮肤病学组合物中的用途，特别是用于抵抗皮肤老化的迹象和/或改善肤色的光泽度和/或 平滑面部和/或身体皮肤和/或治疗皮肤上的皱纹和细纹和/或刺激表皮更新过程。

    Compounds derived from benzoic acid esters, composition containing said compounds and use thereof
    10.
    发明授权
    Compounds derived from benzoic acid esters, composition containing said compounds and use thereof 有权
    衍生自苯甲酸酯的化合物，含有所述化合物的组合物及其用途

    公开(公告)号：US06602869B1

    公开(公告)日：2003-08-05

    申请号：US09937654

    申请日：2001-11-21

    申请人： Jean-Baptiste Galey ,  Maria Dalko ,  Lionel Breton

    发明人： Jean-Baptiste Galey ,  Maria Dalko ,  Lionel Breton

    IPC分类号： A61K31535

    CPC分类号： C07D295/088 ,  A61K8/44 ,  A61K8/70 ,  A61Q7/00 ,  C07C235/16 ,  C07C251/48

    摘要： This invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or OCOR7, R3 represents an aryl or alkyl halogen, R4 represents an alkyl radical. The invention also relates to a cosmetic composition comprising said compounds and to the use thereof to reduce and/or curb hair loss i.e. to increase and/or stimulate the growth of said hair.

    摘要翻译： 本发明涉及新的式（I）化合物，其中R 1表示聚合物，芳基或烷基，R 2表示氢原子，卤素原子，CN，CF 3，OH，OCF 3，COOH，R 7，OR 7或OCOR 7， R3表示芳基或烷基卤素，R4表示烷基。 本发明还涉及包含所述化合物的化妆品组合物及其用于减少和/或抑制脱发的用途，即增加和/或刺激所述头发的生长。