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公开(公告)号:US20090077681A1
公开(公告)日:2009-03-19
申请号:US12115986
申请日:2008-05-06
申请人: Mark C. Fishman , John Mably
发明人: Mark C. Fishman , John Mably
IPC分类号: C12Q1/68 , C07K14/435 , C07H21/00 , C12N15/63 , C12N5/06 , A01K67/027 , C07K16/00
CPC分类号: G01N33/5088 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2227/40 , A01K2267/03 , C07K14/461 , C12Q1/6883 , C12Q2600/156
摘要: The invention provides methods of diagnosing heart disease, such as heart failure, methods for identifying compounds that can be used to treat or to prevent heart disease, and methods of using these compounds to treat or to prevent heart disease. Also provided in the invention are animal model systems that can be used in screening methods.
摘要翻译: 本发明提供诊断心脏病如心力衰竭的方法,用于鉴定可用于治疗或预防心脏病的化合物的方法,以及使用这些化合物治疗或预防心脏病的方法。 本发明还提供了可用于筛选方法的动物模型系统。