摘要:
The invention provides a compound of formula I: wherein R1, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of preventing or treating a herpesvirus infection using such compounds or salts.
摘要:
The present invention provides a compound of formula I Wherein R1 is C1-7 alkyl, optionally substituted by hydroxy or NR4R5; R2 is C1-7 alkyl substituted by hydroxy or NR4R5; R3 is H, F or C1-7 alkoxy; R4 and R5 together with N are a 5- or 6-membered heterocyclic moiety having 1-3 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur in which sulfur may be substituted by one (1) or two (2) oxygen atoms; and pharmaceutically acceptable salts thereof Compounds of formula I of the present invention are useful as antiviral agents.
摘要翻译:本发明提供式I化合物,其中R 1为任选被羟基或NR 4 R 5取代的C 1-7烷基; R2是被羟基或NR4R5取代的C1-7烷基; R3是H,F或C1-7烷氧基; R 4和R 5与N一起是具有1-3个选自氮,氧和硫的杂原子的5-或6-元杂环部分,其中硫可以被一个(1)或两个(2)氧原子取代 ; 本发明式I化合物可用作抗病毒剂。
摘要:
A surface cleaning apparatus comprises a fluid delivery system including a supply of cleaning fluid and a fluid recovery system for drawing dirty cleaning fluid from the surface to be cleaned. The apparatus can comprise a passageway that passes heated motor cooling air in heat exchange with the cleaning fluid to heat the cleaning fluid. The apparatus can further comprise a mixing manifold that mixes first and second cleaning fluids at different concentrations for different cleaning modes. The apparatus can further comprise a fluid valve having a shape memory alloy actuator.
摘要:
The present invention is directed to a water heater which includes a water container; an element located to heat water in the water container; a sensor located to sense temperature proximate the element; and a controller connected to the element and the sensor, the controller being programmed to energize the element with at least one electrical pulse over a predetermined time interval, comparing temperature information received from the sensor with a predetermined temperature, and disengaging the element in the event that the temperature received from the sensor is greater than a predetermined temperature for the predetermined time interval.
摘要:
A canister vacuum cleaner comprises a base, a recovery tank, and a clean solution tank. The vacuum cleaner can be used for dry vacuuming, wet vacuuming, and can distribute cleaning solution to a floor surface and has means for a fluid distribution system and a recovery system. The clean solution tank can be filled with a cleaning solution for distribution to a floor surface and the recovery tank is used for collecting dry or liquid matter recovered from vacuuming.
摘要:
The invention provides a compound of formula I: wherein R1, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of preventing or treating a herpesvirus infection using such compounds or salts.