公开(公告)号：US5258404A

公开(公告)日：1993-11-02

申请号：US945718

申请日：1992-09-16

申请人： Isao Ichinose ,  Masanori Minoguchi ,  Satoru Kumazawa ,  Eyji Yoshida

发明人： Isao Ichinose ,  Masanori Minoguchi ,  Satoru Kumazawa ,  Eyji Yoshida

IPC分类号： A01N37/42 ,  C07C45/65 ,  C07C49/657 ,  C07C49/697 ,  C07C67/343 ,  C07C67/475 ,  C07C69/757 ,  C07C201/12 ,  C07C205/53 ,  C07C253/30 ,  C07C255/57 ,  A01N37/34 ,  C07C205/00 ,  C07C255/00

CPC分类号： C07C69/757

摘要： Disclosed is a 3-(unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivative as represented by the general formula (I): ##STR1## where R.sup.1 and R.sup.2 are each a lower alkyl group;X is a halogen atom, a cyano group, an alkyl group, a haloalkyl group, a phenyl group or a nitro group; andm is 0 or an integer from 1 to 5 and when m is greater than 1 each X can be the same or different.Further, disclosed is a method for the preparation of the compound (I) by carrying out the benzylation, rearrangement, and alkylation from the 2-oxocyclopentane carboxylic acid alkyl ester derivative without isolation of any intermediate compound. In addition, a fungicide is provided in which the 3-(unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives (I) is contained as an active ingredient.Furthermore, it can provide 2-(unsubstituted or substituted benzyl)-5-alkylcyclopentanone derivatives from the 3-(unsubstituted or substituted benzyl)-1-alkyl-2-oxocyclopentane carboxylic acid alkyl ester derivatives (I).

公开(公告)号：US5321038A

公开(公告)日：1994-06-14

申请号：US35102

申请日：1993-03-19

申请人： Masanori Minoguchi ,  Satoru Kumazawa

发明人： Masanori Minoguchi ,  Satoru Kumazawa

IPC分类号： A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/60 ,  C07D249/08 ,  C07D303/16 ,  C07D521/00 ,  A01N43/50 ,  C07D405/10

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/56 ,  C07D249/08 ,  C07D303/16

摘要： Disclosed herein is a process for preparing a cis-azole derivative represented by the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 denote each a hydrogen atom or an alkyl group, R denotes a halogen atom, a nitro group, a cyano group, an alkyl group, a haloalkyl group or a phenyl group, A denotes a nitrogen atom or a methine group, and n stands for an integer of 1-5, which comprises reducing an azolylmethyloxabicyclohexane derivative represented by the general formula (VI) ##STR2## wherein R.sup.1, R.sup.2, R, A and n have the same meanings as defined above. A fungicidal composition comprising the azolylmethyloxabicyclohexane derivative represented by the above-mentioned general formula (VI) is also desclosed.

摘要翻译： 本文公开了一种制备由通式（I）表示的顺 - 唑衍生物的方法，其中R 1和R 2各自表示氢原子或烷基，R表示卤素原子，硝基， 氰基，烷基，卤代烷基或苯基，A表示氮原子或次甲基，n表示1-5的整数，其包括将通式（VI）表示的唑基甲基氧杂双环己烷衍生物 ）其中R1，R2，R，A和n具有与上述相同的含义。 包含由上述通式（VI）表示的唑基甲氧基二环己烷衍生物的杀真菌组合物也被排除。

公开(公告)号：US5225430A

公开(公告)日：1993-07-06

申请号：US798716

申请日：1991-11-29

申请人： Masanori Minoguchi ,  Satoru Kumazawa

发明人： Masanori Minoguchi ,  Satoru Kumazawa

IPC分类号： A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/60 ,  C07D249/08 ,  C07D303/16 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/56 ,  C07D249/08 ,  C07D303/16

摘要： Disclosed herein is a process for preparing a cis-azole derivative represented by the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 denote each a hydrogen atom or an alkyl group, R denotes a halogen atom, a nitro group, a cyano group, an alkyl group, a haloalkyl group or a phenyl group, A denotes a nitrogen atom or a methine group, and n stands for an integer of 1-5,which comprises reducing an azolylmethyloxabicyclohexane derivative represented by the general formula (VI) ##STR2## wherein R.sup.1, R.sup.2, R, A and n have the same meanings as defined above. A fungicidal composition comprising the azolylmethyloxabicyclohexane derivative represented by the above-mentioned general formula (VI) is also desclosed.

公开(公告)号：US5223531A

公开(公告)日：1993-06-29

申请号：US933032

申请日：1992-08-20

申请人： Satoru Kumazawa ,  Masanori Minoguchi

发明人： Satoru Kumazawa ,  Masanori Minoguchi

IPC分类号： A61K31/39 ,  A01N43/26 ,  A01N43/50 ,  A01N43/653 ,  A61P31/04 ,  C07D233/60 ,  C07D249/08 ,  C07D327/10 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/26 ,  C07D233/56 ,  C07D249/08 ,  C07D327/10

摘要： Disclosed is a 1,3,2-dioxathiolan-S-oxide derivative as represented by the general formula (I): ##STR1## (where R.sub.1 and R.sub.2 are identical to or different from each other and each is a hydrogen atom or a lower alkyl group;X is a halogen atom, a cyano group, a lower alkyl group, a haloalkyl group or a phenyl group;m is 0 or an integer from 1 to 5; and when small m is greater than 1 each x can be the same or different andn is 1 or 2).A 1,3,2-dioxathiolan-2-oxide derivative of the compound as represented by the general formula (I-I) is prepared by reacting a hydroxymethylcyclopentanol derivative with thionyl chloride; and a 1,3,2-dioxathiolan-2,2-dioxide derivative (I-II) thereof is prepared by oxidizing the compound (I-I). The compounds (I) can be employed as fungicides and intermediate compounds for the preparation of azolylmethylcyclopentanol derivatives.

公开(公告)号：US08309733B2

公开(公告)日：2012-11-13

申请号：US13001843

申请日：2009-07-01

申请人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

发明人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

IPC分类号： C07D417/04

CPC分类号： C07D277/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/78 ,  A01N47/18 ,  A01N47/24 ,  A01N47/36 ,  C07D277/32 ,  C07D401/06 ,  C07D401/14 ,  C07D417/06 ,  C07D417/14

摘要： [Technical Problem]To provide a novel imino derivative capable of being an insecticide compound having excellent characteristics such as sustained effects and broad spectrum.[Solution to Problem]To provide an imino derivative represented by Formula (1). wherein “Ar” denotes a heterocyclic group which may have a substituent on the ring; “X” denotes a sulfur atom or CH2, NR; “R” denotes a hydrogen atom or an alkyl group; “Y” is selected from COR1 or CONR3R4, CONHCOR5, CO2R9; and each of “R1”, “R3”, “R4”, “R5”, and “R9” denotes a hydrogen atom or a certain substituent.

摘要翻译： 技术问题提供能够成为具有优异特性如持续效果和广谱的杀虫剂化合物的新型亚氨基衍生物。 [问题的解决方案]提供由式（1）表示的亚氨基衍生物。 其中Ar表示可在环上具有取代基的杂环基; X表示硫原子或CH 2，NR; R表示氢原子或烷基; Y选自COR1或CONR3R4，CONHCOR5，CO2R9; R 1，R 3，R 4，R 5和R 9分别表示氢原子或某些取代基。

公开(公告)号：US20110172433A1

公开(公告)日：2011-07-14

申请号：US13001843

申请日：2009-07-01

申请人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

发明人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

IPC分类号： C07D417/04

CPC分类号： C07D277/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/78 ,  A01N47/18 ,  A01N47/24 ,  A01N47/36 ,  C07D277/32 ,  C07D401/06 ,  C07D401/14 ,  C07D417/06 ,  C07D417/14

摘要： [Technical Problem] To provide a novel imino derivative capable of being an insecticide compound having excellent characteristics such as sustained effects and broad spectrum.[Solution to Problem] To provide an imino derivative represented by Formula (1). wherein “Ar” denotes a heterocyclic group which may have a substituent on the ring; “X” denotes a sulfur atom or CH2, NR; “R” denotes a hydrogen atom or an alkyl group; “Y” is selected from COR1 or CONR3R4, CONHCOR5, CO2R9; and each of “R1”, “R3”, “R4”, “R5”, and “R9” denotes a hydrogen atom or a certain substituent.

摘要翻译： 技术问题提供能够成为具有优异特性如持续效果和广谱的杀虫剂化合物的新型亚氨基衍生物。 [问题的解决方案]提供由式（1）表示的亚氨基衍生物。 其中“Ar”表示可在环上具有取代基的杂环基; “X”表示硫原子或CH 2，NR; “R”表示氢原子或烷基; “Y”选自COR1或CONR3R4，CONHCOR5，CO2R9; “R1”，“R3”，“R4”，“R5”和“R9”表示氢原子或某一取代基。

公开(公告)号：US06271385B1

公开(公告)日：2001-08-07

申请号：US09508347

申请日：2000-03-10

申请人： Atsushi Ito ,  Satoru Kumazawa ,  Keiichi Sudo ,  Tsumoru Watanabe ,  Takayoshi Eizuka ,  Yoshitaka Niizeki

发明人： Atsushi Ito ,  Satoru Kumazawa ,  Keiichi Sudo ,  Tsumoru Watanabe ,  Takayoshi Eizuka ,  Yoshitaka Niizeki

IPC分类号： A01N5718

CPC分类号： A01N43/78 ,  A01N43/36 ,  A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/80

摘要： N-heterocyclicmethylpropylamine derivatives of formula (I): and acid addition salts thereof; wherein R1 represents hydrogen, halogen, alkyl, alkenyl, halogenated alkyl, alkoxy, halogenated alkoxy, hydroxyl, cyano, nitro, phenyl optionally having a substituent on a ring thereof or phenoxy; n represents an integer of 0-5; R2 represents a heterocycle containing at least one nitrogen atom as the hetero atom and optionally having a substituent on a ring thereof; and R3 represents hydrogen or C1-C5 alkyl.

摘要翻译： 式（I）的N-杂环甲基丙胺衍生物及其酸加成盐;其中R1表示氢，卤素，烷基，烯基，卤代烷基，烷氧基，卤代烷氧基，羟基，氰基，硝基，任选在其环上具有取代基的苯基 或苯氧基; n表示0〜5的整数。 R2表示含有至少一个氮原子作为杂原子并且在其环上任选具有取代基的杂环; 并且R 3表示氢或C 1 -C 5烷基。

公开(公告)号：US5446167A

公开(公告)日：1995-08-29

申请号：US321093

申请日：1994-10-11

申请人： Shoichiro Hayashi ,  Kazuhiko Sunagawa ,  Satoru Kumazawa

发明人： Shoichiro Hayashi ,  Kazuhiko Sunagawa ,  Satoru Kumazawa

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07B63/00 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： A process for separating a cis isomer from a mixture of the cis isomer and a trans isomer of an azolylmethylcyclopentanol derivative of the formula (I): ##STR1## wherein, R.sup.1 and R.sup.2 each independently represent a hydrogen atom or an alkyl group; each X represents a halogen atom, an alkyl group, a haloalkyl group, a phenyl group, a cyano group or a nitro group; n is an integer of from 0 to 5; A represents a nitrogen atom or a CH group; and each X may be identical or different when n is an integer of from 2 to 5, comprising the steps of dehydrating selectively the trans isomer in the presence of an acid and isolating the cis isomer.

摘要翻译： 从式（I）的吡唑基甲基环戊醇衍生物的顺式异构体和反式异构体的混合物中分离顺式异构体的方法：其中，R 1和R 2各自独立地表示氢原子或烷基 ; 每个X表示卤素原子，烷基，卤代烷基，苯基，氰基或硝基; n为0〜5的整数， A表示氮原子或CH基团; 并且当n是2至5的整数时，每个X可以相同或不同，包括在酸的存在下选择性地脱水反式异构体并分离顺式异构体的步骤。

公开(公告)号：US5099029A

公开(公告)日：1992-03-24

申请号：US648043

申请日：1991-01-30

申请人： Hiroyuki Enari ,  Satoru Kumazawa ,  Susumu Shimizu ,  Atsushi Ito ,  Nobuo Sato ,  Toshihide Saishoji

发明人： Hiroyuki Enari ,  Satoru Kumazawa ,  Susumu Shimizu ,  Atsushi Ito ,  Nobuo Sato ,  Toshihide Saishoji

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/58 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： An azole derivative represented by the formula (I): ##STR1## wherein X and Y independently represent a halogen atom, a phenyl group or a hydrogen atom, providing that at least one of X and Y is not a hydrogen atom, n represents an integer of 0, 1 or 2, and A represents a nitrogen atom or CH, and an agricultural/horticultural fungicide comprising the azole derivative as an active ingredient are disclosed.The azole derivative exhibits an excellent effect in preventing and curing a wide spectrum of plant diseases and possesses low toxicity to mammals.

公开(公告)号：US20120277440A1

公开(公告)日：2012-11-01

申请号：US13520668

申请日：2011-01-06

申请人： Shinzo Kagabu ,  Satoru Kumazawa ,  Tsumoru Watanabe ,  Taiji Miyake ,  Masahiro Nomura ,  Satoshi Nakamura ,  Masaaki Mitomi

发明人： Shinzo Kagabu ,  Satoru Kumazawa ,  Tsumoru Watanabe ,  Taiji Miyake ,  Masahiro Nomura ,  Satoshi Nakamura ,  Masaaki Mitomi

IPC分类号： C07D417/06

CPC分类号： C07D417/06 ,  A01N43/78 ,  C07D417/14

摘要： To provide a novel imino derivative capable of being an insecticide compound which is excellent in characteristics such as sustained effects and a broad spectrum.An imino derivative represented by Formula (A) shown below: wherein “Ar” represents a heterocyclic group which may have a substituent on the ring, “X” represents a sulfur atom or CH2, NR; “R” represents a hydrogen atom or an alkyl group; “Ya” is selected from “C(═S)NR1R2”, “C(═S)SR3”, “C(═O)SR4”, “C(═S)OR4”, “SO2Zα”, and “OZβ”; and, each of “R1” to “R4”, “Zα”, and “Zβ” represents a hydrogen atom or a certain substituent; is provided.

摘要翻译： 提供能够成为持续效果和广谱特性优异的杀虫剂化合物的新型亚氨基衍生物。 由下式（A）表示的亚氨基衍生物：其中Ar表示可在环上具有取代基的杂环基，X表示硫原子或CH2，NR; R表示氢原子或烷基; Ya选自C（= S）NR1R2，C（= S）SR3，C（= O）SR4，C（= ORS）OR4，SO2Zα和OZ。 并且R 1至R 4，Z a和Z bb中的每一个; 表示氢原子或某一取代基; 被提供。