公开(公告)号：US20120277440A1

公开(公告)日：2012-11-01

申请号：US13520668

申请日：2011-01-06

申请人： Shinzo Kagabu ,  Satoru Kumazawa ,  Tsumoru Watanabe ,  Taiji Miyake ,  Masahiro Nomura ,  Satoshi Nakamura ,  Masaaki Mitomi

发明人： Shinzo Kagabu ,  Satoru Kumazawa ,  Tsumoru Watanabe ,  Taiji Miyake ,  Masahiro Nomura ,  Satoshi Nakamura ,  Masaaki Mitomi

IPC分类号： C07D417/06

CPC分类号： C07D417/06 ,  A01N43/78 ,  C07D417/14

摘要： To provide a novel imino derivative capable of being an insecticide compound which is excellent in characteristics such as sustained effects and a broad spectrum.An imino derivative represented by Formula (A) shown below: wherein “Ar” represents a heterocyclic group which may have a substituent on the ring, “X” represents a sulfur atom or CH2, NR; “R” represents a hydrogen atom or an alkyl group; “Ya” is selected from “C(═S)NR1R2”, “C(═S)SR3”, “C(═O)SR4”, “C(═S)OR4”, “SO2Zα”, and “OZβ”; and, each of “R1” to “R4”, “Zα”, and “Zβ” represents a hydrogen atom or a certain substituent; is provided.

摘要翻译： 提供能够成为持续效果和广谱特性优异的杀虫剂化合物的新型亚氨基衍生物。 由下式（A）表示的亚氨基衍生物：其中Ar表示可在环上具有取代基的杂环基，X表示硫原子或CH2，NR; R表示氢原子或烷基; Ya选自C（= S）NR1R2，C（= S）SR3，C（= O）SR4，C（= ORS）OR4，SO2Zα和OZ。 并且R 1至R 4，Z a和Z bb中的每一个; 表示氢原子或某一取代基; 被提供。

公开(公告)号：US08309733B2

公开(公告)日：2012-11-13

申请号：US13001843

申请日：2009-07-01

申请人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

发明人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

IPC分类号： C07D417/04

CPC分类号： C07D277/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/78 ,  A01N47/18 ,  A01N47/24 ,  A01N47/36 ,  C07D277/32 ,  C07D401/06 ,  C07D401/14 ,  C07D417/06 ,  C07D417/14

摘要： [Technical Problem]To provide a novel imino derivative capable of being an insecticide compound having excellent characteristics such as sustained effects and broad spectrum.[Solution to Problem]To provide an imino derivative represented by Formula (1). wherein “Ar” denotes a heterocyclic group which may have a substituent on the ring; “X” denotes a sulfur atom or CH2, NR; “R” denotes a hydrogen atom or an alkyl group; “Y” is selected from COR1 or CONR3R4, CONHCOR5, CO2R9; and each of “R1”, “R3”, “R4”, “R5”, and “R9” denotes a hydrogen atom or a certain substituent.

摘要翻译： 技术问题提供能够成为具有优异特性如持续效果和广谱的杀虫剂化合物的新型亚氨基衍生物。 [问题的解决方案]提供由式（1）表示的亚氨基衍生物。 其中Ar表示可在环上具有取代基的杂环基; X表示硫原子或CH 2，NR; R表示氢原子或烷基; Y选自COR1或CONR3R4，CONHCOR5，CO2R9; R 1，R 3，R 4，R 5和R 9分别表示氢原子或某些取代基。

公开(公告)号：US20110172433A1

公开(公告)日：2011-07-14

申请号：US13001843

申请日：2009-07-01

申请人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

发明人： Shinzo Kagabu ,  Masaru Mori ,  Satoru Kumazawa

IPC分类号： C07D417/04

CPC分类号： C07D277/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/78 ,  A01N47/18 ,  A01N47/24 ,  A01N47/36 ,  C07D277/32 ,  C07D401/06 ,  C07D401/14 ,  C07D417/06 ,  C07D417/14

摘要： [Technical Problem] To provide a novel imino derivative capable of being an insecticide compound having excellent characteristics such as sustained effects and broad spectrum.[Solution to Problem] To provide an imino derivative represented by Formula (1). wherein “Ar” denotes a heterocyclic group which may have a substituent on the ring; “X” denotes a sulfur atom or CH2, NR; “R” denotes a hydrogen atom or an alkyl group; “Y” is selected from COR1 or CONR3R4, CONHCOR5, CO2R9; and each of “R1”, “R3”, “R4”, “R5”, and “R9” denotes a hydrogen atom or a certain substituent.

摘要翻译： 技术问题提供能够成为具有优异特性如持续效果和广谱的杀虫剂化合物的新型亚氨基衍生物。 [问题的解决方案]提供由式（1）表示的亚氨基衍生物。 其中“Ar”表示可在环上具有取代基的杂环基; “X”表示硫原子或CH 2，NR; “R”表示氢原子或烷基; “Y”选自COR1或CONR3R4，CONHCOR5，CO2R9; “R1”，“R3”，“R4”，“R5”和“R9”表示氢原子或某一取代基。

公开(公告)号：US06271385B1

公开(公告)日：2001-08-07

申请号：US09508347

申请日：2000-03-10

申请人： Atsushi Ito ,  Satoru Kumazawa ,  Keiichi Sudo ,  Tsumoru Watanabe ,  Takayoshi Eizuka ,  Yoshitaka Niizeki

发明人： Atsushi Ito ,  Satoru Kumazawa ,  Keiichi Sudo ,  Tsumoru Watanabe ,  Takayoshi Eizuka ,  Yoshitaka Niizeki

IPC分类号： A01N5718

CPC分类号： A01N43/78 ,  A01N43/36 ,  A01N43/40 ,  A01N43/54 ,  A01N43/56 ,  A01N43/80

摘要： N-heterocyclicmethylpropylamine derivatives of formula (I): and acid addition salts thereof; wherein R1 represents hydrogen, halogen, alkyl, alkenyl, halogenated alkyl, alkoxy, halogenated alkoxy, hydroxyl, cyano, nitro, phenyl optionally having a substituent on a ring thereof or phenoxy; n represents an integer of 0-5; R2 represents a heterocycle containing at least one nitrogen atom as the hetero atom and optionally having a substituent on a ring thereof; and R3 represents hydrogen or C1-C5 alkyl.

摘要翻译： 式（I）的N-杂环甲基丙胺衍生物及其酸加成盐;其中R1表示氢，卤素，烷基，烯基，卤代烷基，烷氧基，卤代烷氧基，羟基，氰基，硝基，任选在其环上具有取代基的苯基 或苯氧基; n表示0〜5的整数。 R2表示含有至少一个氮原子作为杂原子并且在其环上任选具有取代基的杂环; 并且R 3表示氢或C 1 -C 5烷基。

公开(公告)号：US5446167A

公开(公告)日：1995-08-29

申请号：US321093

申请日：1994-10-11

申请人： Shoichiro Hayashi ,  Kazuhiko Sunagawa ,  Satoru Kumazawa

发明人： Shoichiro Hayashi ,  Kazuhiko Sunagawa ,  Satoru Kumazawa

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07B63/00 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： A process for separating a cis isomer from a mixture of the cis isomer and a trans isomer of an azolylmethylcyclopentanol derivative of the formula (I): ##STR1## wherein, R.sup.1 and R.sup.2 each independently represent a hydrogen atom or an alkyl group; each X represents a halogen atom, an alkyl group, a haloalkyl group, a phenyl group, a cyano group or a nitro group; n is an integer of from 0 to 5; A represents a nitrogen atom or a CH group; and each X may be identical or different when n is an integer of from 2 to 5, comprising the steps of dehydrating selectively the trans isomer in the presence of an acid and isolating the cis isomer.

摘要翻译： 从式（I）的吡唑基甲基环戊醇衍生物的顺式异构体和反式异构体的混合物中分离顺式异构体的方法：其中，R 1和R 2各自独立地表示氢原子或烷基 ; 每个X表示卤素原子，烷基，卤代烷基，苯基，氰基或硝基; n为0〜5的整数， A表示氮原子或CH基团; 并且当n是2至5的整数时，每个X可以相同或不同，包括在酸的存在下选择性地脱水反式异构体并分离顺式异构体的步骤。

公开(公告)号：US5099029A

公开(公告)日：1992-03-24

申请号：US648043

申请日：1991-01-30

申请人： Hiroyuki Enari ,  Satoru Kumazawa ,  Susumu Shimizu ,  Atsushi Ito ,  Nobuo Sato ,  Toshihide Saishoji

发明人： Hiroyuki Enari ,  Satoru Kumazawa ,  Susumu Shimizu ,  Atsushi Ito ,  Nobuo Sato ,  Toshihide Saishoji

IPC分类号： A01N43/50 ,  A01N43/653 ,  C07D233/58 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  A01N43/50 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： An azole derivative represented by the formula (I): ##STR1## wherein X and Y independently represent a halogen atom, a phenyl group or a hydrogen atom, providing that at least one of X and Y is not a hydrogen atom, n represents an integer of 0, 1 or 2, and A represents a nitrogen atom or CH, and an agricultural/horticultural fungicide comprising the azole derivative as an active ingredient are disclosed.The azole derivative exhibits an excellent effect in preventing and curing a wide spectrum of plant diseases and possesses low toxicity to mammals.

公开(公告)号：US5681979A

公开(公告)日：1997-10-28

申请号：US609374

申请日：1996-03-01

申请人： Hajime Hoshi ,  Satoru Kumazawa

发明人： Hajime Hoshi ,  Satoru Kumazawa

IPC分类号： C07C67/343 ,  C07B61/00 ,  C07C69/757 ,  C07C201/12 ,  C07C205/61 ,  C07C253/30 ,  C07C255/57 ,  C07D233/60 ,  C07D249/08 ,  C07C69/76

CPC分类号： C07C69/757

摘要： The present invention provides a process for producing alkylcyclopentanone derivatives of formula (1) by reacting alkyl cyclopentanone derivatives of formula (2) and alkyl halides of formula (3) in an organic solvent in the presence of molecular sieves and an alkaline metal hydroxide: ##STR1## wherein R.sup.1 is C.sub.1 -C.sub.4 alkyl group; R.sup.2 is hydrogen atom or C.sub.1 -C.sub.5 alkyl group; R.sup.3 is C.sub.1 -C.sub.5 alkyl group; Y is halogen atom, C.sub.1 -C.sub.5 alkyl group, C.sub.1 -C.sub.5 haloalkyl group, phenyl group, cyano group or nitro group; n is an integer from 0 to 5; when n is 2 or greater, Y's may be identical or different; R.sup.3 in formula (3) is the same as R.sup.3 in formula (1); and a process for preparing alkylcyclopentanone derivatives of formula (5) by reacting cyclopentanone derivatives of formula (4) and alkyl halides of formula (6) in an organic solvent in the presence of molecular sieves and an alkaline metal hydroxide: ##STR2## wherein R.sup.1 is C.sub.1 -C.sub.4 alkyl group; R.sup.4 is hydrogen atom or C.sub.1 -C.sub.5 alkyl group; R.sup.5 is C.sub.1 -C.sub.5 alkyl group; R.sup.k is either R.sup.4 or R.sup.5 ; Y is halogen atom, C.sub.1 -C.sub.5 alkyl group, C.sub.1 -C.sub.5 haloalkyl group, phenyl group, cyano group or nitro group; n is an integer from 0 to 5; when n is 2 or greater, Y's may be identical or different.

摘要翻译： 本发明提供了在分子筛和碱金属氢氧化物的存在下，通过使式（2）的烷基环戊酮衍生物与式（3）的烷基卤衍生物在有机溶剂中反应制备式（1）的烷基环戊酮衍生物的方法： （1）图像（2）R3X（3）其中R1是C1-C4烷基; R2是氢原子或C1-C5烷基; R3是C1-C5烷基; Y是卤素原子，C1-C5烷基，C1-C5卤代烷基，苯基，氰基或硝基; n为0〜5的整数， 当n为2以上时，Y可以相同或不同; 式（3）中的R 3与式（1）中的R 3相同; （4）的环戊酮衍生物和式（6）的烷基卤在有机溶剂中在分子筛和碱金属氢氧化物存在下制备式（5）的烷基环戊酮衍生物的方法： （5）RkX（6）其中R1是C1-C4烷基; R4是氢原子或C1-C5烷基; R5是C1-C5烷基; Rk是R4或R5; Y是卤素原子，C1-C5烷基，C1-C5卤代烷基，苯基，氰基或硝基; n为0〜5的整数， 当n为2以上时，Y可以相同也可以不同。

公开(公告)号：US5468869A

公开(公告)日：1995-11-21

申请号：US124763

申请日：1993-09-22

申请人： Satoru Kumazawa ,  Hiroyuki Enari

发明人： Satoru Kumazawa ,  Hiroyuki Enari

IPC分类号： A01N43/50 ,  A01N43/653 ,  A61K31/41 ,  A61K31/415 ,  A61P31/04 ,  C07D233/60 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： This invention provides a simple process for production of an (azolylmethyl)(biphenylmethyl)cyclopentanol derivative represented by the following formula (I) in a good yield. This process comprises, as described in the following reaction formula, reacting an (azolylmethyl)(halogenophenylmethyl)cyclopentanol derivative represented by the following formula (II) with a benzene derivative represented by the following formula (III) by light irradiation. ##STR1## wherein X denotes a halogen atom, R.sup.1 and R.sup.2 denote independently a hydrogen atom or a C1-C5 alkyl group, R.sup.3 denotes a C1-C5 alkyl group, n means an integer of 0-2, and A represents CH or N.

摘要翻译： 本发明提供以良好的产率制备由下式（I）表示的（唑基甲基）（联苯甲基）环戊醇衍生物的简单方法。 该方法如下述反应式所示，通过光照射使由下式（II）表示的（唑基甲基）（卤代苯基甲基）环戊醇衍生物与下式（III）表示的苯衍生物反应。 其中X表示卤素原子，R1和R2分别独立地表示氢原子或C1-C5烷基，R3表示C1-C5烷基，n表示0〜2的整数，A表示 CH或N.

公开(公告)号：US5321038A

公开(公告)日：1994-06-14

申请号：US35102

申请日：1993-03-19

申请人： Masanori Minoguchi ,  Satoru Kumazawa

发明人： Masanori Minoguchi ,  Satoru Kumazawa

IPC分类号： A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/60 ,  C07D249/08 ,  C07D303/16 ,  C07D521/00 ,  A01N43/50 ,  C07D405/10

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07C33/34 ,  C07C33/40 ,  C07D233/56 ,  C07D249/08 ,  C07D303/16

摘要： Disclosed herein is a process for preparing a cis-azole derivative represented by the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 denote each a hydrogen atom or an alkyl group, R denotes a halogen atom, a nitro group, a cyano group, an alkyl group, a haloalkyl group or a phenyl group, A denotes a nitrogen atom or a methine group, and n stands for an integer of 1-5, which comprises reducing an azolylmethyloxabicyclohexane derivative represented by the general formula (VI) ##STR2## wherein R.sup.1, R.sup.2, R, A and n have the same meanings as defined above. A fungicidal composition comprising the azolylmethyloxabicyclohexane derivative represented by the above-mentioned general formula (VI) is also desclosed.

摘要翻译： 本文公开了一种制备由通式（I）表示的顺 - 唑衍生物的方法，其中R 1和R 2各自表示氢原子或烷基，R表示卤素原子，硝基， 氰基，烷基，卤代烷基或苯基，A表示氮原子或次甲基，n表示1-5的整数，其包括将通式（VI）表示的唑基甲基氧杂双环己烷衍生物 ）其中R1，R2，R，A和n具有与上述相同的含义。 包含由上述通式（VI）表示的唑基甲氧基二环己烷衍生物的杀真菌组合物也被排除。

公开(公告)号：US5162356A

公开(公告)日：1992-11-10

申请号：US666488

申请日：1991-03-06

申请人： Masato Arahira ,  Toshihide Saishoji ,  Susumu Ikeda ,  Satoru Kumazawa

发明人： Masato Arahira ,  Toshihide Saishoji ,  Susumu Ikeda ,  Satoru Kumazawa

IPC分类号： A61K31/415 ,  A61P31/04 ,  A61P31/10 ,  C07D233/60 ,  C07D233/61 ,  C07D249/08 ,  C07D521/00

CPC分类号： C07D231/12 ,  C07D233/56 ,  C07D249/08

摘要： Disclosed herein are azole derivatives or the salts thereof which are represented by the general formula (I): ##STR1## wherein X represents a halogen atom, an alkyl group having 1 to 5 carbon atoms, a haloalkyl group, a phenyl group, a cyano group, or a nitro group, Xs being either the same or different from each other; n represents an integer of 1 to 5; A represents a nitrogen atom or CH; and one of R.sub.1 and R.sub.2 represents an alkyl group having 1 to 5 carbon atoms and the other a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, with the proviso that when n is 1 or 2, X does not represent a halogen atom, an alkyl group having 1 to 5 carbon atoms or a phenyl group, and mycocides comprising an effective amount of azole derivative or medically or veterinarily acceptable salt thereof, said azole derivative being represented by the general formula (II): ##STR2## wherein X represents a halogen atom, an alkyl group having 1 to 5 carbon atoms, a haloalkyl group, a phenyl group, a cyano group, or a nitro group, Xs being either the same or different from each other; n represents an integer of 0 to 5; A represents a nitrogen atom or CH; and R.sub.1 and R.sub.2 respectively represent a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, and a diluent or a carrier which is medically or veterinarily acceptable.

摘要翻译： 本文公开的是由通式（I）表示的唑衍生物或其盐：其中X表示卤素原子，具有1至5个碳原子的烷基，卤代烷基，苯基 ，氰基或硝基，Xs彼此相同或不同; n表示1〜5的整数， A表示氮原子或CH; R1和R2之一表示碳原子数为1〜5的烷基，另一个为氢原子或碳原子数为1〜5的烷基，条件是当n为1或2时，X不表示卤素 原子，具有1〜5个碳原子的烷基或苯基，以及包含有效量的唑衍生物或其医学上或兽医学上可接受的盐的霉菌，所述唑衍生物由通式（II）表示： II）其中X表示卤素原子，具有1至5个碳原子的烷基，卤代烷基，苯基，氰基或硝基，X可以相同或不同; n表示0〜5的整数， A表示氮原子或CH; R 1和R 2分别表示氢原子或碳原子数1〜5的烷基，以及在医学上或兽医学上可接受的稀释剂或载体。