公开(公告)号：US20160319464A1

公开(公告)日：2016-11-03

申请号：US14701218

申请日：2015-04-30

Applicant: Massachusetts Institute of Technology

Inventor： Alexander H. Slocum ,  Nicholas M. Sondej ,  Bernhardt Levy Trout ,  Gregory C. Rutledge ,  Indrani Bhattacharyya

IPC: D01D5/00 ,  D01D7/00

CPC classification number: D01D5/0076 ,  A61J3/00 ,  A61J3/10 ,  A61K9/2095 ,  B05B5/025

Abstract: Methods and systems for manufacturing a tablet are generally provided. Certain embodiments comprise electrodepositing (e.g., electrospinning) a material (e.g., the tablet material, for example, within a fluid) onto a substrate. The substrate can be, for example, an elongated rod. In some such embodiments, after material has been electrodeposited onto the substrate, a die comprising a cavity and the substrate can be moved relative to each other such that the electrodeposited material is at least partially stripped from the substrate and/or at least partially deposited into the cavity of the die. Some embodiments comprise compressing the material in the cavity to form a tablet.

Abstract translation: 通常提供用于制造片剂的方法和系统。 某些实施方案包括将材料（例如，将片剂材料例如在流体内）电沉积（例如静电纺丝）到基底上。 基底可以是例如细长的杆。 在一些这样的实施例中，在材料已经电沉积到基底上之后，包括空腔和基底的模具可以相对于彼此移动，使得电沉积材料至少部分地从基底剥离和/或至少部分地沉积到 模具的腔体。 一些实施例包括压缩空腔中的材料以形成片剂。

公开(公告)号：US10053798B2

公开(公告)日：2018-08-21

申请号：US14701218

申请日：2015-04-30

Applicant: Massachusetts Institute of Technology

Inventor： Alexander H. Slocum ,  Nicholas M. Sondej ,  Bernhardt Levy Trout ,  Gregory C. Rutledge ,  Indrani Bhattacharyya

IPC: B05B5/025 ,  D01D5/00 ,  A61J3/00 ,  A61K9/20 ,  A61J3/10

CPC classification number: D01D5/0076 ,  A61J3/00 ,  A61J3/10 ,  A61K9/2095 ,  B05B5/025

Abstract: Methods and systems for manufacturing a tablet are generally provided. Certain embodiments comprise electrodepositing (e.g., electrospinning) a material (e.g., the tablet material, for example, within a fluid) onto a substrate. The substrate can be, for example, an elongated rod. In some such embodiments, after material has been electrodeposited onto the substrate, a die comprising a cavity and the substrate can be moved relative to each other such that the electrodeposited material is at least partially stripped from the substrate and/or at least partially deposited into the cavity of the die. Some embodiments comprise compressing the material in the cavity to form a tablet.