专利检索 ap:("Massachusetts Institute of Technology" OR "École Polytechnique Fédérale de Lausanne") AND inv:"Francesco Stellacci" 第 1 页

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发明申请
NANOPARTICLES COMPRISING A METAL CORE SURROUNDED BY A MONOLAYER FOR LYMPH NODE TARGETING 审中-公开

公开(公告)号：US20180311174A1

公开(公告)日：2018-11-01

申请号：US15770442

申请日：2016-10-24

申请人： Massachusetts Institute of Technology , École Polytechnique Fédérale de Lausanne

发明人： Darrell J. Irvine , Yu-Sang Sabrina Yang , Ahmet Bekdemir , Francesco Stellacci

IPC分类号： A61K9/51 , A61K47/69

CPC分类号： A61K9/5115 , A61K9/0029 , A61K9/5123 , A61K38/00 , A61K47/6923 , A61K47/6929

摘要： Amphiphilic gold nanoparticles (amph-NPs), composed of gold cores surrounded by an amphiphilic mixed organic ligand shell, are capable of embedding within and traversing lipid membranes. Active agent is bound thereto for use in vaccine and other adjuvant therapies, immunomodulation, and treatment of microbial infections, cancer, autoimmune disease, inflammation and inflammatory disorders.