公开(公告)号：US20130122291A2

公开(公告)日：2013-05-16

申请号：US13250786

申请日：2011-09-30

申请人： Matthew Casebolt ,  Robert Murphy

发明人： Matthew Casebolt ,  Robert Murphy

IPC分类号： B32B7/12 ,  B32B37/12

CPC分类号： C09J7/0296 ,  B32B37/1284 ,  B32B37/206 ,  B32B2309/105 ,  B32B2405/00 ,  C09J7/29 ,  C09J2201/128 ,  C09J2203/326 ,  C09J2467/006 ,  Y10T156/10 ,  Y10T428/14 ,  Y10T428/1476 ,  Y10T428/1481 ,  Y10T428/15 ,  Y10T428/28 ,  Y10T428/2848

摘要： An adhesive stack comprises a shear layer positioned between two adhesive layers. The shear layer, comprised of a weak adhesive sub-layer positioned between substrate sub-layers, is designed to fail upon application of a deliberate and appropriate shear force and before the failure of the adhesive layers. The adhesive sub-layer defines a width and/or length less than a width and/or length of another layer or sub-layer of the adhesive stack. The adhesive stack aids in securing components within an electronic device to prevent movement of the component when the device is dropped, hit, or bumped. The adhesive stack may occupy minimal space within the device, and reduce the cost of securing the component within the device's interior. The adhesive stack may allow for replacement of the component by an authorized person applying an appropriate and deliberate force. The adhesive stack may aid in identifying components replaced by an unauthorized person.

摘要翻译： 粘合剂堆叠包括位于两个粘合剂层之间的剪切层。 设置在位于衬底子层之间的弱粘合剂子层的剪切层被设计成在施加有意和适当的剪切力并且在粘合剂层失效之前失效。 粘合剂子层限定了小于粘合剂叠层的另一层或子层的宽度和/或长度的宽度和/或长度。 粘合剂叠层有助于将元件固定在电子设备内，以防止在设备掉落，撞击或碰撞时组件的移动。 粘合剂堆叠可能占用设备内的最小空间，并降低将部件固定在设备内部的成本。 粘合剂堆可以允许授权的人员使用适当的和故意的力来更换部件。 粘合剂层可以帮助识别由未经授权的人更换的部件。

公开(公告)号：US08618400B2

公开(公告)日：2013-12-31

申请号：US12468220

申请日：2009-05-19

申请人： Cary Murphy ,  Robert Murphy

发明人： Cary Murphy ,  Robert Murphy

IPC分类号： G10H1/00

CPC分类号： G10H1/348 ,  G10H2220/315 ,  G10H2220/371 ,  G10H2220/395 ,  G10H2240/311

摘要： An electronic musical instrument controller is constructed by fixing sensors and transducers to sections of a chair, allowing a user to map motion of body, arms, head, hands, fingers, and feet to parameters of a musical instrument such as a hardware or software electronic music synthesizer. The mapping may take place over MIDI, control voltage, computer connection, or other means of interfacing.

摘要翻译： 电子乐器控制器通过将传感器和换能器固定在椅子的部分上而构成，允许用户将身体，手臂，头部，手，手指和脚的运动映射到乐器的参数，例如硬件或软件电子 音乐合成器。 映射可以通过MIDI，控制电压，计算机连接或其他接口方式进行。

公开(公告)号：US20120252687A1

公开(公告)日：2012-10-04

申请号：US13079489

申请日：2011-04-04

申请人： Richard A. Friesner ,  Robert Murphy

发明人： Richard A. Friesner ,  Robert Murphy

IPC分类号： C40B30/04

CPC分类号： G16C20/50 ,  G16B15/00

摘要： A method of scoring binding affinity of a proposed ligand molecule for a receptor molecule using a computer and computer data bases, which accounts for the increase in energy required where docking disrupts water molecules that are localized or localized. The method uses computer-stored data representing a predicted ligand-receptor structure (preferably one that is validated) as well as computer-stored data representing a library of compounds to be tested. Data representing members of the compound library is analyzed by computerized operations which determine whether the receptor in the predicted ligand-receptor structure includes a) determining whether the receptor in the predicted ligand-receptor structure includes solvating water molecule(s) whose desolvation into the surrounding environment requires substantial energy, b) determining whether a docking configuration for a member of the compound library with the receptor requires desolvation of one or more of the desolvating water molecule(s), and, if so, assigning a desolvation penalty to the member of the compound library.

摘要翻译： 使用计算机和计算机数据库评估所提出的配体分子对受体分子的结合亲和力的方法，其考虑到对接破坏定位或定位的水分子所需的能量的增加。 该方法使用表示预测的配体 - 受体结构（优选经过验证的）的计算机存储的数据以及表示待测化合物文库的计算机存储的数据。 通过计算机操作来分析表示化合物文库的成员的数据，其确定预测的配体 - 受体结构中的受体是否包括a）确定预测的配体 - 受体结构中的受体是否包含溶解到周围的溶剂化水分子 环境需要大量的能量，b）确定化合物文库与受体的成员的对接构型是否需要脱溶剂中的一种或多种去溶质水分子，如果是，则将脱溶剂处罚分配给 复合库。

公开(公告)号：US08160820B2

公开(公告)日：2012-04-17

申请号：US12152067

申请日：2008-05-12

申请人： Richard A. Friesner ,  Robert Murphy

发明人： Richard A. Friesner ,  Robert Murphy

IPC分类号： G06F19/10

CPC分类号： G06F19/706 ,  G06F19/16 ,  G06F19/707

摘要： Scoring functions can be markedly improved by taking into account the status environs of ligand rings (or indeed other bulky rigid ligand structures) on the ligand when the ligand is complexed with the receptor. In its most general form, the invention features, quantifying a particular component of binding affinity between a ligand and a receptor molecule. Specifically, the component in question takes into account the spatial relationship between ligand ring structure(s) (or bulky rigid ligand structures) and their ambient surroundings when the ligand is bound to the receptor molecule. The method steps may be used when quantifying a component that reflects these particular ligand features alone, or the steps may be part of a comprehensive method of quantifying binding affinity which includes numerous other factors that relate to binding affinity in addition to the component. For example, one may calculate an initial binding affinity and then adjust the initial binding affinity by a factor obtained at least in part based on the classification of the ring structure.

摘要翻译： 当配体与受体复合时，通过考虑配体环（或实际上其它体积大的刚性配体结构）在配体上的状态环境，可以显着改善评分功能。 在其最通用形式中，本发明的特征在于定量配体和受体分子之间的结合亲和力的特定组分。 具体来说，当配体与受体分子结合时，所讨论的组分考虑了配体环结构（或体积大的刚性配体结构）及其周围环境之间的空间关系。 当量化单独反映这些特定配体特征的组分时，可以使用方法步骤，或者步骤可以是量化结合亲和力的全面方法的一部分，其包括与组分相关的结合亲和力相关的许多其它因子。 例如，可以计算初始结合亲和力，然后基于环结构的分类至少部分获得的因子来调整初始结合亲和力。

公开(公告)号：US07597393B1

公开(公告)日：2009-10-06

申请号：US10819341

申请日：2004-04-05

申请人： Eugene M. Tuccinardi ,  Ernesto R. Haack ,  Robert Murphy ,  Shanna Murphy, legal representative ,  Frank Barrese ,  Roel C. Espina ,  Jon A. Molo ,  Theo Zoetemelk

发明人： Eugene M. Tuccinardi ,  Ernesto R. Haack ,  Robert Murphy ,  Frank Barrese ,  Roel C. Espina ,  Jon A. Molo ,  Theo Zoetemelk

IPC分类号： A47C7/42

CPC分类号： B60R11/0235 ,  B60R11/0211 ,  B60R2011/0017 ,  B60R2011/008

摘要： A seat back video display assembly adapted to be positioned in the back of a vehicle seat having an outer skin cover. In one aspect, the assembly may comprise a receptacle member having sidewalls and a back wall so as to define an opening wherein the receptacle member is adapted to be positioned in the back of the vehicle seat. In addition, the assembly may further comprise a carrier member having sidewalls and a back wall so as to define an opening, wherein the carrier member includes at least one fastener that extends from the back wall of the carrier member and engages with the back wall of the receptacle member to secure the carrier member into the receptacle member. Moreover, the assembly may still further comprise a video display unit that is sized so as to be positioned secured within the opening in the carrier member, wherein the video display unit provides video signals.

摘要翻译： 一种座椅靠背视频显示组件，其适于定位在具有外护罩的车辆座椅的后部。 在一个方面，组件可以包括具有侧壁和后壁以便限定开口的容器构件，其中容器构件适于定位在车辆座椅的后部。 此外，组件还可以包括具有侧壁和后壁以便限定开口的承载构件，其中承载构件包括至少一个紧固件，该紧固件从承载构件的后壁延伸并与 所述容器构件将所述承载构件固定到所述容器构件中。 此外，组件还可以包括视频显示单元，其尺寸设计成被固定在承载构件中的开口内，其中视频显示单元提供视频信号。

公开(公告)号：US07484438B2

公开(公告)日：2009-02-03

申请号：US11637323

申请日：2006-12-12

申请人： Robert Murphy

发明人： Robert Murphy

IPC分类号： B25B17/00

CPC分类号： E21B4/006 ,  B23Q5/045 ,  B25B13/481 ,  B25B17/00 ,  B25B17/02 ,  E21B19/081 ,  E21B19/083

摘要： A right angle driving apparatus capable of operable attachment to a powered rotational drive device such as a drill, the driving apparatus being generally comprised of a worm gear drive encased within a unique block-shaped housing. The subject driving apparatus may be employed to transmit power at high velocity ratios between a shaft that is driven by the drill to a wheel having an axis of rotation perpendicular to that of the shaft. The worm gear drive may be used as a speed increaser but is preferably used as a speed reducer in which the worm is the driver and the wheel is the driven member. The worm wheel is slidably mounted on a cylindrical hub adapted to receive in either end a variety of driving tools such as sockets and screwdriver blades used to rotate fasteners. The worm wheel is driven by a worm attached to a drive shaft the journaled end of which may be adapted to receive driving tools as well to permit direct driving of tools in addition to right angle driving.

摘要翻译： 一种能够可操作地附接到诸如钻头的动力旋转驱动装置的直角驱动装置，所述驱动装置通常包括封装在独特的块形壳体内的蜗轮传动装置。 主体驱动装置可以用于在由钻头驱动的轴与具有垂直于轴的旋转轴线的轮之间以高速比传递动力。 蜗轮传动装置可以用作增速器，但优选用作减速器，其中蜗杆是驱动器，而车轮是从动件。 蜗轮可滑动地安装在圆柱形毂上，适于在任一端接收各种驱动工具，例如用于旋转紧固件的插座和螺丝刀。 蜗轮由附接到驱动轴的蜗杆驱动，驱动轴的轴颈可适用于接收驱动工具，并允许除了直角驱动之外直接驱动工具。

公开(公告)号：US20070141696A1

公开(公告)日：2007-06-21

申请号：US11313091

申请日：2005-12-19

申请人： Brenton Baugh ,  Robert Murphy

发明人： Brenton Baugh ,  Robert Murphy

IPC分类号： C12M3/00 ,  G01N33/558

CPC分类号： G01N21/01

摘要： A diagnostic test reader includes an assay interface, a locking mechanism, and a test unit. The assay interface is configured to receive a diagnostic assay. The locking mechanism is configured to lock the diagnostic assay within the assay interface in response to one of the diagnostic assay and the diagnostic test reader being given a first push in a first direction toward the other of the diagnostic assay and the diagnostic test reader. The locking mechanism is also configured to unlock the diagnostic assay within the assay interface in response to the one of the diagnostic assay and the diagnostic test reader being given a second push in the first direction. The test unit is configured to analyze the diagnostic assay.

摘要翻译： 诊断测试读取器包括测定界面，锁定机构和测试单元。 测定界面被配置为接收诊断测定。 锁定机构被配置为响应于诊断测定中的一个和诊断测试读取器中的一个，在第一方向上向诊断测定和诊断测试读取器中的另一个进行第一推动来将诊断测定锁定在测定界面内。 锁定机构还被配置为响应于诊断测试和诊断测试读取器中的一个在第一方向被给予第二推动而在测定界面内解锁诊断测定。 测试单元被配置为分析诊断测定。

公开(公告)号：US20070061118A1

公开(公告)日：2007-03-15

申请号：US11373684

申请日：2006-03-10

申请人： Richard Friesner ,  Robert Murphy

发明人： Richard Friesner ,  Robert Murphy

IPC分类号： G06G7/48 ,  G06G7/58

CPC分类号： G06F19/706 ,  C40B30/02 ,  G06F19/16 ,  G06F19/18 ,  G06F19/26

摘要： A computer-implemented method for calculating a value representative of interaction (VRI) of a proposed ligand with a specified receptor. Hydrophobic interactions between one or more ligand atoms and one or more receptor atoms are scored by a method that awards a bonus for the presence of hydrophobic enclosure of one or more ligand atoms by the receptor. Also, charge-charge hydrogen bonds between a ligand and a receptor are scored by setting a default value for a charge-charge hydrogen bond and awarding a bonus above the default value when one or more specialized predetermined charge-charge hydrogen bond criteria is satisfied. Various charge-charge hydrogen bond criteria are used. Zwitterions, charge, salvation, geometry and electrostatic energy are accounted for.

摘要翻译： 一种计算机实现的方法，用于计算代表所提及的配体与指定受体的相互作用（VRI）的值。 通过一种方法来评估一个或多个配体原子和一个或多个受体原子之间的疏水相互作用，所述方法为受体的一个或多个配体原子的疏水封闭的存在赋予奖励。 此外，通过设定充电氢氢键的默认值，并且当满足一个或多个专门的预定充电氢键标准时，将奖金高于默认值来评分配体和受体之间的充电氢键。 使用各种充电氢键标准。 两性离子，电荷，溶剂化，几何形状和静电能量。

公开(公告)号：US20060125186A1

公开(公告)日：2006-06-15

申请号：US11306934

申请日：2006-01-17

申请人： Randolph Digges ,  Robert Murphy

发明人： Randolph Digges ,  Robert Murphy

IPC分类号： A63B63/00

CPC分类号： A63B67/06 ,  A63B63/00 ,  A63B2024/0046

摘要： Bag toss game target assemblies that include a deck and a base unit. The deck includes at least one through-aperture dimensioned to allow a bag to pass entirely therethrough. The base unit has a bottom portion that is configured to rest on a generally horizontal surface and a top portion that is configured to support the deck during game play. In one preferred embodiment, the base unit further includes an open-top storage receptacle that is covered by the deck during game play, but can be accessed by moving the deck independent of the base unit. In another preferred embodiment, the deck from at least target assembly can be removed from its corresponding base unit, and the corresponding base unit can be nested beneath and partially within the base unit of another target assembly.

摘要翻译： 袋子折腾包括甲板和基本单元的游戏目标组件。 甲板包括至少一个通孔，其尺寸设计成允许袋子完全通过。 基座单元具有构造成搁置在大致水平的表面上的底部部分和被配置为在游戏过程中支撑甲板的顶部部分。 在一个优选实施例中，基座单元还包括在游戏过程中由甲板覆盖的敞开顶部存储容器，但是可以通过独立于基座单元移动甲板来访问。 在另一个优选实施例中，来自至少目标组件的甲板可以从其对应的基座单元移除，并且相应的基座单元可以嵌套在另一个目标组件的基座单元的下面和部分内。

公开(公告)号：US20060038367A9

公开(公告)日：2006-02-23

申请号：US10796601

申请日：2004-03-09

申请人： Frank Ferraro ,  Robert Murphy

发明人： Frank Ferraro ,  Robert Murphy

IPC分类号： B62B3/00

CPC分类号： A47B87/0253 ,  A47B87/0284

摘要： The various aspects of the present invention are directed to moving carts and moving cart assemblies. One embodiment comprises a moving cart assembly with a plurality of interlocking, vertically stackable, storage modules. The modules of this embodiment comprise a frame, preferably having at least four sides, e.g., a top, a back, a right side and a left side. Each module also comprises something to enclose the interior space, such as a pair of doors or a drawer which is selectively slidable into the frame. The needs of a particular office can be readily accommodated by using greater or fewer numbers of drawer modules and/or cabinet-type modules.