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1.发明申请公开(公告)号：US20110105450A1
公开(公告)日：2011-05-05
申请号：US12794320
申请日：2010-06-04
申请人： Matthew J. Chapin , George Minno , Jackie Nice , Paul Gomes , Mark Barry Abelson
发明人： Matthew J. Chapin , George Minno , Jackie Nice , Paul Gomes , Mark Barry Abelson
CPC分类号： A61K31/40 , A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/10 , A61K47/183 , A61K47/186 , A61K47/38
摘要： The present invention provides ophthalmic formulations of fluticasone that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic conjunctivitis in a subject in need of such treatment by topical application of the fluticasone formulations of the invention directly to the eye.
摘要翻译： 本发明提供氟替卡松的眼用制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明还提供了通过将本发明的氟替卡松制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎和/或过敏性结膜炎的方法。
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公开(公告)号：US08569273B2
公开(公告)日：2013-10-29
申请号：US12888117
申请日：2010-09-22
申请人： Mark Barry Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
发明人： Mark Barry Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
CPC分类号： A61K31/56 , A61K9/0048 , A61K31/135 , A61K31/495
摘要： The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis rhinitis, and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
摘要翻译： 本发明提供了西替利嗪的稳定的局部制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明进一步提供了通过将本发明的西替利嗪制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎鼻炎和/或过敏性鼻结膜炎的方法。
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公开(公告)号：US20110257136A1
公开(公告)日：2011-10-20
申请号：US12888117
申请日：2010-09-22
申请人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
发明人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
CPC分类号： A61K31/56 , A61K9/0048 , A61K31/135 , A61K31/495
摘要： The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis rhinitis, and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
摘要翻译： 本发明提供了西替利嗪的稳定的局部制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明进一步提供了通过将本发明的西替利嗪制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎鼻炎和/或过敏性鼻结膜炎的方法。
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公开(公告)号：US20100240625A1
公开(公告)日：2010-09-23
申请号：US12724128
申请日：2010-03-15
申请人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
发明人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
IPC分类号： A61K31/56 , A61K31/4965 , A61P27/02 , A61P37/08
CPC分类号： A61K31/495 , A61K9/0048 , A61K9/08 , A61K31/4174 , A61K31/4965 , A61K31/56 , A61K31/569 , A61K47/02 , A61K47/10 , A61K47/183 , A61K47/186 , A61K47/26 , A61K47/38
摘要： The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
摘要翻译： 本发明提供了西替利嗪的稳定的局部制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明还提供了通过将本发明的西替利嗪制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎和/或过敏性鼻结膜炎的方法。
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公开(公告)号：US09254286B2
公开(公告)日：2016-02-09
申请号：US12724128
申请日：2010-03-15
申请人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
发明人： Mark B. Abelson , Matthew J. Chapin , Paul Gomes , George Minno , Jackie Nice
IPC分类号： A61K31/495 , A61K9/00 , A61K9/08 , A61K31/4965 , A61K31/56
CPC分类号： A61K31/495 , A61K9/0048 , A61K9/08 , A61K31/4174 , A61K31/4965 , A61K31/56 , A61K31/569 , A61K47/02 , A61K47/10 , A61K47/183 , A61K47/186 , A61K47/26 , A61K47/38
摘要： The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.
摘要翻译： 本发明提供了西替利嗪的稳定的局部制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明还提供了通过将本发明的西替利嗪制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎和/或过敏性鼻结膜炎的方法。
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公开(公告)号：US20100240624A1
公开(公告)日：2010-09-23
申请号：US12701130
申请日：2010-02-05
申请人： Matthew J. Chapin , Mark B. Abelson , George Minno , Jackie Nice , Paul Gomes
发明人： Matthew J. Chapin , Mark B. Abelson , George Minno , Jackie Nice , Paul Gomes
IPC分类号： A61K31/4535 , A61K31/568 , A61P27/02 , A61P27/04 , A61P27/14
CPC分类号： A61K31/4535 , A61K9/0048 , A61K9/08 , A61K31/568
摘要： The present invention provides topical formulations of ketotifen that provide a comfortable formulation when instilled in the eye and are effective in the treatment and prevention of ocular allergy, particularly allergic conjunctivitis. The invention further provides methods of treating and preventing ocular allergy by in a subject in need of such treatment by topical application of the ketotifen formulations of the invention to the eye of a subject in need thereof.
摘要翻译： 本发明提供酮立芬的局部制剂，其在滴入眼睛时提供舒适的制剂，并且有效治疗和预防眼部过敏，特别是过敏性结膜炎。 本发明进一步提供了在需要这种治疗的受试者中治疗和预防眼部过敏的方法，其通过将本发明的酮替芬制剂局部施用于有需要的受试者的眼睛。
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