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17 条记录 (耗时 0.017 秒)

    Ophthalmic compositions and methods of using the same
    2.
    发明申请
    Ophthalmic compositions and methods of using the same 审中-公开
    眼用组合物及其使用方法

    公开(公告)号：US20060148899A1

    公开(公告)日：2006-07-06

    申请号：US11257196

    申请日：2005-10-24

    申请人： Kenneth Green ,  Susan Caballa ,  George Minno

    发明人： Kenneth Green ,  Susan Caballa ,  George Minno

    IPC分类号： A61K31/205

    CPC分类号： A61K9/0048 ,  A61K31/445 ,  A61K31/453 ,  A61K31/4535

    摘要： Ophthalmic compositions are provided that comprise or consist essentially of (a) ketotifen or a ketotifen salt, (b) a non-ionic tonicity agent, and (c) water. The concentration of ketotifen or the ketotifen salt is preferably from 0.01% to 0.05%. The non-ionic tonicity agent is preferably glycerol and the concentration of the glycerol is preferably from 4% to 7%. The compositions preferably have an osmolality of from 400 to 875 milliosmoles/Kg. The compositions may also contain an anti-redness agent. Methods of treating allergic conjunctivitis using the ophthalmic compositions and methods of treating dry eye disease using the ophthalmic compositions are also provided.

    摘要翻译： 提供了包含或基本上由（a）酮替芬或酮替芬盐，（b）非离子张度剂和（c）水）组成或组成的眼科组合物。 酮替芬或酮替芬盐的浓度优选为0.01％至0.05％。 非离子型张力剂优选为甘油，甘油的浓度优选为4％〜7％。 组合物优选具有400至875毫摩尔/ Kg的渗透压浓度。 组合物还可以含有抗发红剂。 还提供了使用眼科组合物治疗过敏性结膜炎的方法和使用眼科组合物治疗干眼病的方法。

    Ophthalmic Formulations Of Cetirizine And Methods Of Use
    7.
    发明申请
    Ophthalmic Formulations Of Cetirizine And Methods Of Use 有权
    西替利嗪的眼科配方及其使用方法

    公开(公告)号：US20110257136A1

    公开(公告)日：2011-10-20

    申请号：US12888117

    申请日：2010-09-22

    申请人： Mark B. Abelson ,  Matthew J. Chapin ,  Paul Gomes ,  George Minno ,  Jackie Nice

    发明人： Mark B. Abelson ,  Matthew J. Chapin ,  Paul Gomes ,  George Minno ,  Jackie Nice

    IPC分类号： A61K31/56 ,  A61P27/14

    CPC分类号： A61K31/56 ,  A61K9/0048 ,  A61K31/135 ,  A61K31/495

    摘要： The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis rhinitis, and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.

    摘要翻译： 本发明提供了西替利嗪的稳定的局部制剂，其在滴注在眼睛中时提供舒适的制剂，并且有效治疗过敏性结膜炎和/或过敏性结膜炎。 本发明进一步提供了通过将本发明的西替利嗪制剂直接局部施用于眼睛来治疗需要这种治疗的受试者的过敏性结膜炎鼻炎和/或过敏性鼻结膜炎的方法。