公开(公告)号：US09791459B2

公开(公告)日：2017-10-17

申请号：US13318797

申请日：2010-05-04

申请人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Ola Didrik Saugstad ,  Therese Koal

发明人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Ola Didrik Saugstad ,  Therese Koal

IPC分类号： G01N33/48 ,  G01N33/68 ,  G06F19/24

CPC分类号： G01N33/6893 ,  G01N2800/12 ,  G06F19/24 ,  Y02A90/26

摘要： A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

公开(公告)号：US06838441B1

公开(公告)日：2005-01-04

申请号：US10110182

申请日：2000-09-15

申请人： Ola Didrik Saugstad ,  Christian André Drevon

发明人： Ola Didrik Saugstad ,  Christian André Drevon

IPC分类号： A61K38/38 ,  A61P11/00

CPC分类号： A61K38/38

摘要： The present invention provides a method of treating meconium aspiration syndrome, said method comprising administering to a subject in need of treatment a therapeutically effective amount of albumin. A further aspect of the invention relates to the use of albumin in the preparation of a medicament for treatment of meconium aspiration syndrome, and a pharmaceutical composition comprising albumin admixed with a pharmaceutically acceptable carrier, diluent or excipient.

摘要翻译： 本发明提供了一种治疗胎粪吸入综合征的方法，所述方法包括向需要治疗的受试者施用治疗有效量的白蛋白。 本发明的另一方面涉及白蛋白在制备用于治疗胎粪吸入综合征的药物中的用途，以及包含与药学上可接受的载体，稀释剂或赋形剂混合的白蛋白的药物组合物。