公开(公告)号：US09791459B2

公开(公告)日：2017-10-17

申请号：US13318797

申请日：2010-05-04

申请人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Ola Didrik Saugstad ,  Therese Koal

发明人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Ola Didrik Saugstad ,  Therese Koal

IPC分类号： G01N33/48 ,  G01N33/68 ,  G06F19/24

CPC分类号： G01N33/6893 ,  G01N2800/12 ,  G06F19/24 ,  Y02A90/26

摘要： A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

公开(公告)号：US20120136581A1

公开(公告)日：2012-05-31

申请号：US13318797

申请日：2010-05-04

申请人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Olga Didrik Saugstad ,  Therese Koal

发明人： Matthias Keller ,  Hans-Peter Deigner ,  David Enot ,  Matthias Kohl ,  Ronnaug Solberg ,  Olga Didrik Saugstad ,  Therese Koal

IPC分类号： G06F19/00

CPC分类号： G01N33/6893 ,  G01N2800/12 ,  G06F19/24 ,  Y02A90/26

摘要： A method for in vitro diagnosing asphyxia and disorders related thereto, a method of in vitro estimating duration of hypoxia in a patient subjected to asphyxia, and a method for in vitro monitoring of normoxic, hypoxic and hyperoxic conditions and/or normobaric and hyperbaric oxygen therapy, includes quantitatively detecting in a biological sample of a patient a plurality of asphyxia specific endogenous compounds which are selected from the group consisting of biogenic amines; carnitine-derived compounds; amino acids; bile acids; carboxylic acids; eicosanoids; lipids; precursors of cholesterol, cholesterol metabolites; prostanoids; and sugars.

摘要翻译： 用于体外诊断与其相关的窒息和障碍的方法，体外估计患有窒息的患者的缺氧持续时间的方法和用于体外监测正常氧，缺氧和高氧条件和/或正常和高压氧治疗的方法 包括定量检测患者的生物样品中多种选自生物胺的窒息特异性内源性化合物; 肉碱衍生化合物; 氨基酸; 胆汁酸 羧酸; 类花生酸 脂质 胆固醇前体，胆固醇代谢物; 前列腺素 和糖。