FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF
    2.
    发明申请
    FLUOROALKYLOXY ALKANES, PROCESS FOR PRODUCTION AND USES THEREOF 审中-公开
    氟烷基铝,其生产工艺及其用途

    公开(公告)号:US20110034414A1

    公开(公告)日:2011-02-10

    申请号:US12937915

    申请日:2008-04-28

    CPC分类号: C07C41/16 C07C43/12

    摘要: The present invention relates to fluoroalkyloxy alkanes having formula (I): RF—R1—O—R2 wherein: RF is a linear or branched perfluoroalkyl group, having from 1 to 12, preferably from 2 to 8, carbon atoms; R1 is a linear or branched, non-fluorinated alkylene group, having from 1 to 6, preferably from 2 to 4, carbon atoms, —R2 is a linear or branched, non-fluorinated alkyl group, having from 1 to 12, preferably from 2 to 8, carbon atoms, possibly containing at least one ether bond —O— along the chain. The present invention further relates to a process for preparation and use thereof, possibly in mixture with at least one silicone oil, as medicaments in ophthalmology, in particular as tamponade liquids in an operation for the treatment of retinal detachment.

    摘要翻译: 本发明涉及具有式(I)的氟代烷氧基烷烃:RF-R 1 -O-R 2其中:RF是具有1至12个,优选2至8个碳原子的直链或支链全氟烷基; R1是具有1至6个,优选2至4个碳原子的直链或支链的非氟化亚烷基,-R2是直链或支链的非氟化烷基,其具有1至12个,优选为 2至8个碳原子,可能含有至少一个沿着链的醚键-O-。 本发明进一步涉及其制备和使用方法,可能与至少一种硅油混合,作为眼科药物,特别是作为治疗视网膜脱离手术的填塞液。