公开(公告)号：US20110137285A1

公开(公告)日：2011-06-09

申请号：US12960186

申请日：2010-12-03

申请人： Mauro BECCARO ,  Enrico BETTINI ,  Paolo SIGNORI

发明人： Mauro BECCARO ,  Enrico BETTINI ,  Paolo SIGNORI

IPC分类号： A61M5/31 ,  A61P35/00 ,  A61K47/08

CPC分类号： A61K31/695 ,  A61K31/02 ,  A61K31/075 ,  A61K31/80 ,  A61K2300/00

摘要： A kit of tamponing liquids comprising a first liquid having a density lower than 1.00 g/cm3 and a second liquid having a density higher than 1.00 g/cm3 which are immiscible with water and, at body temperature, one miscible with the other, for sequential use in the surgical treatment of tears and/or detachments of the retina, and a method for the treatment of tears and/or detachments of the retina using such liquids comprising the steps of injecting first the first liquid, or, respectively, the second liquid, into the vitreous cavity and maintaining it within the vitreous cavity for a determined period of time, thereafter injecting the second liquid, or respectively, the first liquid, into the vitreous cavity to mix with the other liquid and create with the latter a homogeneous solution having a density that is higher or lower than 1.00 g/cm3 respectively, if the first injected liquid had a density that was lower or higher than 1.00 g/cm3.

摘要翻译： 一种沐浴液体，其包含密度低于1.00g / cm 3的第一液体和密度高于1.00g / cm 3的第二液体，其与水不混溶，并且在体温下与另一种物质混溶，用于顺序 用于手术治疗视网膜的撕裂和/或脱离，以及使用这种液体治疗视网膜的眼泪和/或脱离的方法，包括以下步骤：首先注射第一液体，或分别注射第二​​液体 进入玻璃体腔并将其保持在玻璃体腔内一段确定的时间段内，然后将第二液体或分别将第一液体注射到玻璃体腔中以与其他液体混合并与后者一起产生均匀溶液 如果第一注入液体的密度低于或高于1.00g / cm 3，则分别具有高于或低于1.00g / cm 3的密度。

公开(公告)号：US20110060291A1

公开(公告)日：2011-03-10

申请号：US12877192

申请日：2010-09-08

申请人： MAURO BECCARO ,  ENRICO BETTINI ,  PAOLO SIGNORI

发明人： MAURO BECCARO ,  ENRICO BETTINI ,  PAOLO SIGNORI

IPC分类号： A61M5/31

CPC分类号： A61F9/0017 ,  A61F9/00727 ,  A61M5/14526 ,  A61M5/155 ,  A61M5/2053 ,  A61M5/344 ,  A61M5/347 ,  A61M2005/3104

摘要： Device for injecting into an eyeball a sterile liquid selected from amongst perfluorocarbons, comprising a tubular container body (3) having a first dispensing end (5) and a second end (6), and an adapter (4) for connecting a thrust fluid feed tube (6) to the second end (6). A first stopper (17) is inserted into the container body (3) in a sealed fashion and sterile liquid (2) is fed between the first stopper (17) and the first end (5). The adapter (4) consists of first and second connecting means (21), (22) to attach the adapter (4) to a feed tube (20) and to the second end (6), as well as first and second seal means (23), (24) to guarantee the fluid seal between the adapter (4) and the feed tube (20) and the container body (3). A duct (25) for the passage of a thrust fluid extends through the adapter (4) from the feed tube (20) to the container body (3).

摘要翻译： 用于将从全氟化碳中选出的无菌液体注入眼球的装置，包括具有第一分配端（5）和第二端（6）的管状容器主体（3）和用于连接推力流体进料 管（6）到第二端（6）。 第一止动件（17）以密封的方式插入容器主体（3）中，并且无菌液体（2）被供给在第一止动件（17）和第一端（5）之间。 适配器（4）包括将适配器（4）连接到进料管（20）和第二端（6）的第一和第二连接装置（21），（22）以及第一和第二密封装置 （23），（24），以确保适配器（4）和进料管（20）和容器主体（3）之间的流体密封。 用于推进流体通过的管道（25）延伸穿过适配器（4）从进料管（20）延伸到容器主体（3）。

公开(公告)号：US20110034414A1

公开(公告)日：2011-02-10

申请号：US12937915

申请日：2008-04-28

申请人： Lino Conte ,  Mauro Beccaro ,  Enrico Bettini ,  Paolo Signori ,  Alessandro Zaggia

发明人： Lino Conte ,  Mauro Beccaro ,  Enrico Bettini ,  Paolo Signori ,  Alessandro Zaggia

IPC分类号： A61K31/695 ,  C07C43/12 ,  A61K47/24 ,  A61P27/02 ,  A61P41/00

CPC分类号： C07C41/16 ,  C07C43/12

摘要： The present invention relates to fluoroalkyloxy alkanes having formula (I): RF—R1—O—R2 wherein: RF is a linear or branched perfluoroalkyl group, having from 1 to 12, preferably from 2 to 8, carbon atoms; R1 is a linear or branched, non-fluorinated alkylene group, having from 1 to 6, preferably from 2 to 4, carbon atoms, —R2 is a linear or branched, non-fluorinated alkyl group, having from 1 to 12, preferably from 2 to 8, carbon atoms, possibly containing at least one ether bond —O— along the chain. The present invention further relates to a process for preparation and use thereof, possibly in mixture with at least one silicone oil, as medicaments in ophthalmology, in particular as tamponade liquids in an operation for the treatment of retinal detachment.

摘要翻译： 本发明涉及具有式（I）的氟代烷氧基烷烃：RF-R 1 -O-R 2其中：RF是具有1至12个，优选2至8个碳原子的直链或支链全氟烷基; R1是具有1至6个，优选2至4个碳原子的直链或支链的非氟化亚烷基，-R2是直链或支链的非氟化烷基，其具有1至12个，优选为 2至8个碳原子，可能含有至少一个沿着链的醚键-O-。 本发明进一步涉及其制备和使用方法，可能与至少一种硅油混合，作为眼科药物，特别是作为治疗视网膜脱离手术的填塞液。

公开(公告)号：US20100181218A1

公开(公告)日：2010-07-22

申请号：US12669859

申请日：2008-07-23

申请人： Mauro Beccaro ,  Enrico Bettini ,  Paolo Signori

发明人： Mauro Beccaro ,  Enrico Bettini ,  Paolo Signori

IPC分类号： A61B19/02 ,  A61L2/04 ,  A61M5/31 ,  A61M5/315

CPC分类号： A61M5/001 ,  A61F9/0017 ,  A61F9/00727 ,  A61K9/0019 ,  A61K9/0048 ,  A61L2/07 ,  A61M5/002 ,  A61M5/344 ,  A61M5/347 ,  A61M2005/3104 ,  A61M2209/06

摘要： A device for ophthalmic treatments comprises a package (9) forming a housing chamber (9a) inside it, and a syringe (2) inserted in the housing chamber (9a) and filled with a sterile liquid, of the type which can be injected into an eyeball. The liquid (4) is selected from amongst the family of perfluorocarbons. There are also two methods for making the device (1).

摘要翻译： 用于眼科治疗的装置包括在其内形成容纳室（9a）的包装（9）和插入容纳室（9a）中并填充无菌液体的注射器（2），其可以注入 一个眼球。 液体（4）选自全氟化碳族。 还有两种制造设备的方法（1）。