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公开(公告)号:US20240352120A1
公开(公告)日:2024-10-24
申请号:US18442934
申请日:2024-02-15
IPC分类号: C07K16/28 , A61K38/20 , A61K38/21 , A61K39/00 , C07K16/30 , C12N15/113 , C12Q1/6886 , G01N33/50 , G01N33/569 , G01N33/574
CPC分类号: C07K16/2803 , A61K38/2013 , A61K38/2026 , A61K38/2066 , A61K38/208 , A61K38/2086 , A61K38/212 , A61K38/215 , A61K38/217 , C07K16/2827 , C07K16/30 , C12N15/113 , C12N15/1138 , C12Q1/6886 , G01N33/5088 , G01N33/5091 , G01N33/56972 , G01N33/57407 , G01N33/57438 , G01N33/57484 , A61K2039/505 , C07K2317/24 , C07K2317/76 , C12N2310/11 , C12N2310/14 , C12N2320/30 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158
摘要: The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.