公开(公告)号：US20180252724A1

公开(公告)日：2018-09-06

申请号：US15756274

申请日：2016-08-26

Applicant: McMaster University

Inventor： Peter Kavsak ,  Andrew Worster

IPC: G01N33/66 ,  G01N33/72 ,  G01N33/70

CPC classification number: G01N33/66 ,  G01N33/6887 ,  G01N33/70 ,  G01N33/723 ,  G01N33/80 ,  G01N33/92 ,  G01N2333/4712 ,  G01N2333/58 ,  G01N2333/8139 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/56

Abstract: Methods of determining the risk of an adverse cardiovascular event or death in a mammal are provided which include determining in a biological sample obtained from the mammal the level of a combination of biomarkers selected from a glucose metabolism biomarker, a heart function biomarker, a renal function biomarker and at least one biomarker of cardiac injury. A score is allotted based on the level of each biomarker, and the cumulative score is indicative of the risk of an adverse cardiovascular event.