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公开(公告)号:US20230110516A1
公开(公告)日:2023-04-13
申请号:US17908222
申请日:2021-03-01
发明人: John D. CAMPBELL , Robert S. JANSSEN , David NOVACK , Tsun-Yung KUO , Charles CHEN , Chung-Chin WU , Yi-Jiun LIN , Meei-Yun LIN , Yu-Chi WU
IPC分类号: C07K14/005 , A61P31/14 , A61K39/215
摘要: The present disclosure relates to immunogenic compositions comprising a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen, and a toll-like receptor 9 (TLR9) agonist, such as an oligonucleotide comprising an unmethylated cytidine-phospho-guanosine (CpG) motif. The immunogenic compositions are suitable for stimulating an immune response against a SARS-CoV-2 in an individual in need thereof.
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公开(公告)号:US20210308257A1
公开(公告)日:2021-10-07
申请号:US17351363
申请日:2021-06-18
发明人: Tsun-Yung KUO , Charles CHEN , Chung-Chin WU , Yi-Jiun LIN , Meei-Yun Lin , Yu-Chi WU , John Darren CAMPBELL , Robert S. JANSSEN , David NOVACK
IPC分类号: A61K39/215 , C07K14/165 , C07K14/245
摘要: The present invention relates to an immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially to an immunogenic composition having a recombinant SARS-CoV-2 S protein and adjuvant.
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公开(公告)号:US20240197862A1
公开(公告)日:2024-06-20
申请号:US18592811
申请日:2024-03-01
发明人: Charles CHEN , Tsun-Yung Kuo , Chung-Chin Wu , Wei-Hsuan Tang , Chia-En Lien , Yi-Jiun Lin , Meei-Yun Lin
IPC分类号: A61K39/215 , A61K39/00 , A61P37/04 , C12N7/00
CPC分类号: A61K39/215 , A61P37/04 , C12N7/00 , A61K2039/54 , A61K2039/545 , A61K2039/55505 , A61K2039/55561 , C12N2770/20022 , C12N2770/20034 , C12N2770/20071
摘要: The present invention relates to immunogenic compositions and methods for immunization against variants of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), especially to an immunogenic composition having a recombinant SARS-CoV-2 S protein derived from Beta (B.1.351) variant and methods using an immunogenic composition derived from SARS-COV-2 Beta (B.1.351) variant.
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