公开(公告)号：US09289165B2

公开(公告)日：2016-03-22

申请号：US14514829

申请日：2014-10-15

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  Timothy H. Robinson ,  James K. Carney ,  Tara L. Nahey ,  Cygni Chan

IPC: A61N1/36 ,  A61B5/145 ,  A61B5/11 ,  A61B5/1473 ,  A61B5/00 ,  A61N1/365 ,  A61B5/053 ,  A61M5/142 ,  A61M5/172

CPC classification number: A61B5/14546 ,  A61B5/053 ,  A61B5/1107 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/4519 ,  A61B5/686 ,  A61B5/7278 ,  A61B2562/0219 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36135 ,  A61N1/36167 ,  A61N1/36557

Abstract: In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.

公开(公告)号：US20150032023A1

公开(公告)日：2015-01-29

申请号：US14514829

申请日：2014-10-15

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  Timothy H. Robinson ,  James K. Carney ,  Tara L. Nahey ,  Cygni Chan

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/11

CPC classification number: A61B5/14546 ,  A61B5/053 ,  A61B5/1107 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/4519 ,  A61B5/686 ,  A61B5/7278 ,  A61B2562/0219 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36135 ,  A61N1/36167 ,  A61N1/36557

Abstract: In general, the invention is directed to methods and devices for determining an ion concentration in the extracellular fluid of a patient. As examples, the ion may be one or more of potassium, sodium, chloride, or calcium. A system includes an electrode deployed in or near a tissue, such as a skeletal muscle, of the patient. A pulse generator supplies one or more stimulations to the tissue, and a sensor, such as an accelerometer, detects the response of the tissue to the stimulations. A processor determines a concentration of ions in the extracellular fluid as a function of the response. The system may detect an ion imbalance based upon the determined concentration of ions.

Abstract translation: 通常，本发明涉及用于确定患者的细胞外液中的离子浓度的方法和装置。 作为实例，离子可以是钾，钠，氯或钙中的一种或多种。 系统包括部署在患者的组织（例如骨骼肌）中或附近的电极。 脉冲发生器向组织提供一个或多个刺激，并且诸如加速度计的传感器检测组织对刺激的响应。 处理器确定细胞外液中的离子浓度作为响应的函数。 该系统可以基于确定的离子浓度检测离子不平衡。