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1.发明公开公开(公告)号：US20230355965A1
公开(公告)日：2023-11-09
申请号：US18131614
申请日：2023-04-06
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
IPC: A61N1/05
CPC classification number: A61N1/0556 , A61N1/3605
Abstract: System and methods for stimulating or blocking a nerve are provided. The system may include an implantable pulse generator configured to generate a current and an electrode device in communication with the implantable pulse generator and configured to surround the nerve. The electrode device may include a housing comprising an inner surface, a first edge, and a second edge opposite the first edge; at least one electrode disposed on the inner surface and configured to apply the current to the nerve; and at least one closure configured to couple the first edge to the second edge to form a seal.
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公开(公告)号：US20240139516A1
公开(公告)日：2024-05-02
申请号：US18050872
申请日：2022-10-28
Applicant: Medtronic, Inc.
Inventor： James Britton Hissong , Robert T. Sandgren , Erik J. Peterson , Sean P. Skubitz , Adam J. Rivard , Thomas I. Miller , David J. Miller , Kristin N. Hageman , Avram Scheiner , Kanthaiah Koka , Leonid M. Litvak
CPC classification number: A61N1/36139 , A61N1/025 , A61N1/3606
Abstract: A system includes memory, and processing circuitry coupled to the memory, the processing circuitry configured to: determine at least one of: a cross-electrical signal measurement at a first electrode on a first lead implanted within a tongue of the patient based on a stimulation signal between a second electrode on the first lead or a second lead implanted within the tongue of the patient and a third electrode, or a strain measurement of at least one of the first lead or the second lead. The processing circuitry is configured to determine movement of the tongue based on at least one of the cross-electrical signal measurement or the strain measurement, and generate information indicative of the movement of the tongue.
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3.发明公开公开(公告)号：US20230355969A1
公开(公告)日：2023-11-09
申请号：US18132219
申请日：2023-04-07
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
CPC classification number: A61N1/36007 , A61N1/0507 , A61N1/37247 , A61B5/14532 , A61B5/7435 , G16H10/40
Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, a device may be configured to generate a current, and an electrode device coupled to the device may be configured to apply the current to the anatomical element. Additionally, the system may include a user interface in communication with the implantable pulse generator, the electrode device, or both. In some examples, the user interface may include a first element that is configured to display information associated with the patient. Additionally, the user interface may include a second element that is configured to receive inputs for programming parameters of the current. The user interface may also include a third element that is configured to display diagnostic information associated with applying the current to the anatomical element.
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4.发明公开公开(公告)号：US20230355141A1
公开(公告)日：2023-11-09
申请号：US18132204
申请日：2023-04-07
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
CPC classification number: A61B5/14532 , G16H20/17
Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, the system may include a device (e.g., an implantable pulse generator) and an electrode device electrically coupled to the device. In some examples, the device may be configured to generate a current that is to be applied to the anatomical element via the electrode device to stimulate the anatomical element as part of a therapy aimed at achieving or supporting glycemic control in the patient. Additionally, the current may be applied to the anatomical element based on a machine learning algorithm that uses inputs gathered for determining one or more characteristics for the current. Accordingly, the machine learning algorithm may be configured to determine the one or more characteristics for the current specific to the patient (e.g., to provide personalized therapy settings for the patient).
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5.发明公开公开(公告)号：US20230302276A1
公开(公告)日：2023-09-28
申请号：US17656586
申请日：2022-03-25
Applicant: Medtronic, Inc.
Inventor： Leonid M. Litvak , Avram Scheiner , Kristin N. Hageman , Kanthaiah Koka , James Britton Hissong , Erik J. Peterson , David J. Miller , Robert T. Sandgren , Adam J. Rivard , Sean P. Skubitz , Thomas I. Miller
CPC classification number: A61N1/36003 , A61N1/0548 , A61N1/37235 , A61N1/36139
Abstract: A medical system for obstructive sleep apnea (OSA) treatment includes therapy delivery circuitry configured to output one or more electrical stimulation signals to a tongue of a patient; sensing circuitry configured to sense one or more compound muscle action potential (CMAP) signals, wherein the one or more CMAP signals are generated in response to the delivery of the one or more electrical stimulation signals; and processing circuitry configured to: cause the therapy delivery circuitry to output the one or more electrical stimulation signals to the tongue; receive information indicative of the one or more CMAP signals from the sensing circuitry; determine, based on the one or more CMAP signals, one or more therapeutic stimulation parameters for the OSA treatment; and cause the therapy delivery circuitry to deliver therapeutic electrical stimulation signals according to at least the determined one or more therapeutic stimulation parameters.
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Patent Agency Ranking
公开(公告)号：US20230355987A1
公开(公告)日：2023-11-09
申请号：US18131500
申请日：2023-04-06
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
CPC classification number: A61N1/36185 , A61N1/025 , A61N1/36053 , A61N1/0558
Abstract: Systems and methods for stimulating an anatomical element are provided. The system may comprise an implantable pulse generator configured to generate a current and an electrode device comprising a plurality of electrodes configured to apply the current to the anatomical element. Each of the plurality of electrodes may comprise at least one of an anode or a cathode. The electrode device may be customized by assigning each of the plurality of electrodes as at least one of an anode or a cathode and at least one of active or inactive. The current may be applied to the anatomical element in a predetermined pattern using the plurality of electrodes.
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公开(公告)号：US20230355982A1
公开(公告)日：2023-11-09
申请号：US18132232
申请日：2023-04-07
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
CPC classification number: A61N1/36139 , A61N1/025 , A61N1/0551 , A61N1/36053
Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, the system may include a device configured to generate a current (e.g., implantable pulse generator), a first electrode device configured to apply the current to the anatomical element, and a second electrode device configured to record one or more response measurements associated with applying the current to the anatomical element. In some examples, the one or more response measurements may be used to generate growth curves associated with applying the current to the anatomical element, where the growth curves can be used to adjust one or more parameters of the current. Additionally, the one or more response measurements may include an evoked compound action potential (eCAP) measurement, an electromyography (EMG) measurement, a glucose level measurement, or a combination thereof.
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公开(公告)号：US20230355981A1
公开(公告)日：2023-11-09
申请号：US18131592
申请日：2023-04-06
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , Shaileshkumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
IPC: A61N1/36
CPC classification number: A61N1/36139 , A61N1/36053
Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, a device may be configured to generate a current, and an electrode device coupled to the device may be configured to apply the current to the anatomical element. In some examples, the current may be configured to prevent hypoglycemic episodes from occurring in the patient when applied to the anatomical element. For example, the current may be configured to downregulate neural activity of a celiac vagal trunk and to upregulate neural activity of a hepatic vagal trunk. Accordingly, the current being applied to anatomical element of the patient may result in a decrease in insulin production of the patient, an increase in glucose production of the patient, an increase in blood sugar levels of the patient, or a combination thereof. Additionally, applying the current may prevent nocturnal hypoglycemic episodes from occurring.
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公开(公告)号：US20230355976A1
公开(公告)日：2023-11-09
申请号：US18131576
申请日：2023-04-06
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
CPC classification number: A61N1/36053 , A61N1/0556 , A61B5/14532
Abstract: A system is provided herein for stimulating an anatomical element of a patient to regulate insulin production of the patient. In some examples, the system may include a device configured to generate a current and an electrode device electrically coupled to the device. Subsequently, the device may receive instructions to apply the current to the anatomical element via a plurality of electrodes of the electrode device, where the current is configured to regulate insulin production of the patient. For example, a first electrode may be configured for placement on or around a celiac vagal trunk, where the current downregulates neural activity of the celiac vagal trunk, and a second electrode may be configured for placement on or around a hepatic vagal trunk, where the current upregulates neural activity of the hepatic vagal trunk.
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10.发明公开公开(公告)号：US20230355975A1
公开(公告)日：2023-11-09
申请号：US18131555
申请日：2023-04-06
Applicant: Medtronic, Inc.
Inventor： Maneesh Shrivastav , ShaileshKumar V. Musley , Kanthaiah Koka , Steven M. Goetz , Suryakiran Vadrevu , Rebecca K. Gottlieb , David John Miller , Leonid M. Litvak
IPC: A61N1/36
CPC classification number: A61N1/36053 , A61N1/36146
Abstract: A system is provided herein for stimulating an anatomical element of a patient to achieve glycemic control for the patient. In some examples, the system may include a device configured to generate a current and an electrode device electrically coupled to the device that includes a plurality of electrodes configured for placement on or around the anatomical element. The device may receive instructions to apply the current to the anatomical element via the plurality of electrodes of the electrode device. Additionally, the current may be applied using a first waveform of a plurality of waveforms that the device is capable of generating, where each of the plurality of waveforms comprise a substantially similar charge density. Additionally or alternatively, a system is provided that provides a pharmacological blockade at the anatomical element using a micropump that is configured to deliver a pharmacological agent to the anatomical element to achieve glycemic control.
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