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公开(公告)号:US12168085B2
公开(公告)日:2024-12-17
申请号:US17306053
申请日:2021-05-03
Applicant: MEDTRONIC INC.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/375 , A61N1/39
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating includes a polymer, collagen, glycerin and a hemostatic agent. The polymer is selected from the group of polyhydroxybutyrate, polyglycerol sebacate and adducts of polyglycerol sebacate. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20230079760A1
公开(公告)日:2023-03-16
申请号:US17473119
申请日:2021-09-13
Applicant: MEDTRONIC INC.
Inventor: JONATHAN T. GOODMAN , Sean Chen , Kasyap V. Seethamraju , Charlene X. Yuan , Raman V. Bahulekar
Abstract: A surgical device includes a substrate and a first coating that covers at least a portion of the substrate. The first coating includes a first polymer. The first coating having antibiotics dispersed in the first polymer such that the first polymer releases the antibiotics as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second polymer. The second coating has ellagic acid dispersed in the second polymer such that the second polymer releases the ellagic acid as the second polymer degrades. In some embodiments, systems and methods are disclosed.
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公开(公告)号:US20240245835A1
公开(公告)日:2024-07-25
申请号:US18423951
申请日:2024-01-26
Applicant: Medtronic, Inc.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/375 , A61N1/39
CPC classification number: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/37512 , A61L2300/204 , A61L2300/21 , A61L2300/216 , A61L2300/252 , A61L2300/406 , A61L2300/418 , A61L2400/04 , A61N1/3956
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating including collagen, glycerin and a hemostatic agent. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20220211915A1
公开(公告)日:2022-07-07
申请号:US17306053
申请日:2021-05-03
Applicant: MEDTRONIC INC.
Inventor: SEAN CHEN , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L27/54 , A61L27/34 , A61K31/195 , A61K31/496 , A61K31/65
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating includes a polymer, collagen, glycerin and a hemostatic agent. The polymer is selected from the group of polyhydroxybutyrate, polyglycerol sebacate and adducts of polyglycerol sebacate. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20230077402A1
公开(公告)日:2023-03-16
申请号:US17473123
申请日:2021-09-13
Applicant: MEDTRONIC INC.
Inventor: JONATHAN T. GOODMAN , Sean Chen , Kasyap V. Seethamraju , Charlene X. Yuan , Raman V. Bahulekar , Joseph L. Kalscheuer
IPC: A61L31/10 , A61L31/14 , A61L31/16 , A61K31/196 , A61K31/496 , A61K31/65
Abstract: A surgical device includes a substrate and a first coating that covers at least a portion of the substrate. The first coating includes a first polymer. The first coating having antibiotics dispersed in the first polymer such that the first polymer releases the antibiotics as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second polymer. The second polymer includes an alginate. The second coating has a hemostatic agent dispersed in the second polymer such that the second polymer releases the hemostatic agent as the second polymer degrades. The hemostatic agent is selected from epinephrine, tranexamic acid, chitosan and oxidized regenerated cellulose. In some embodiments, systems and methods are disclosed.
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公开(公告)号:US20220211921A1
公开(公告)日:2022-07-07
申请号:US17142725
申请日:2021-01-06
Applicant: MEDTRONIC INC.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating including collagen, glycerin and a hemostatic agent. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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