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公开(公告)号:US20240245835A1
公开(公告)日:2024-07-25
申请号:US18423951
申请日:2024-01-26
Applicant: Medtronic, Inc.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/375 , A61N1/39
CPC classification number: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/37512 , A61L2300/204 , A61L2300/21 , A61L2300/216 , A61L2300/252 , A61L2300/406 , A61L2300/418 , A61L2400/04 , A61N1/3956
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating including collagen, glycerin and a hemostatic agent. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20220211915A1
公开(公告)日:2022-07-07
申请号:US17306053
申请日:2021-05-03
Applicant: MEDTRONIC INC.
Inventor: SEAN CHEN , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L27/54 , A61L27/34 , A61K31/195 , A61K31/496 , A61K31/65
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating includes a polymer, collagen, glycerin and a hemostatic agent. The polymer is selected from the group of polyhydroxybutyrate, polyglycerol sebacate and adducts of polyglycerol sebacate. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20220211921A1
公开(公告)日:2022-07-07
申请号:US17142725
申请日:2021-01-06
Applicant: MEDTRONIC INC.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating including collagen, glycerin and a hemostatic agent. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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公开(公告)号:US20250152332A1
公开(公告)日:2025-05-15
申请号:US18945912
申请日:2024-11-13
Applicant: Medtronic, Inc.
Inventor: Jonathan T. Goodman , Shanthi John Lawrence , Charlene X. Yuan , Daniel R. Lexcen
Abstract: An implantable medical device includes a mesh substrate. A first coating that covers at least a portion of the substrate. The first coating includes a first biodegradable or bioresorbable polymer. The first coating has a chemotherapeutic agent dispersed in the first polymer such that the first polymer releases the agent as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second biodegradable or bioresorbable polymer. The second coating has an antibiotic agent dispersed in the second polymer such that the second polymer releases the agent as the second polymer degrades. The first coating is configured to release the chemotherapeutic agent over about 10-180 days and the second coating is configured to release the antibiotic agent over about 3-10 days.
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公开(公告)号:US12168085B2
公开(公告)日:2024-12-17
申请号:US17306053
申请日:2021-05-03
Applicant: MEDTRONIC INC.
Inventor: Sean Chen , Kirsten R. Stark , Satish Pulapura , Kasyap V. Seethamraju , Jonathan T. Goodman , DanThanh H. Le
IPC: A61L31/10 , A61K31/195 , A61K31/496 , A61K31/65 , A61L27/34 , A61L27/54 , A61L31/16 , A61N1/375 , A61N1/39
Abstract: A surgical system including an implantable medical device having a size and shape. The surgical device having a substrate and a coating that covers at least a portion of the substrate. The coating includes a polymer, collagen, glycerin and a hemostatic agent. The polymer is selected from the group of polyhydroxybutyrate, polyglycerol sebacate and adducts of polyglycerol sebacate. The substrate including a first piece and a second piece that is joined with the first piece. The first piece and the second piece forming a pocket having a cavity and an opening that is in communication with the cavity. The device being pre-formed such that a size and shape of the cavity conforms to the size and shape of the implantable medical device.
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