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公开(公告)号:US20130171197A1
公开(公告)日:2013-07-04
申请号:US13338800
申请日:2011-12-28
申请人: Mei-Ling Ho , Rajalakshmanan Eswaramoorthy , Shun-Cheng Wu , Gwo-Jaw Wang , Je-Ken Chang , Yin-Chih Fu , Cherng-Chyi Tzeng , Chau-Zen Wang
发明人: Mei-Ling Ho , Rajalakshmanan Eswaramoorthy , Shun-Cheng Wu , Gwo-Jaw Wang , Je-Ken Chang , Yin-Chih Fu , Cherng-Chyi Tzeng , Chau-Zen Wang
CPC分类号: C12N5/0068 , A61K47/36 , C12N5/0667 , C12N2533/40 , C12N2533/80 , C12N2537/10
摘要: The present invention provides a hydrogel comprising a poly(N-isopropylacrylamide) cross-linked hyaluronic acid. The present invention also provides a method of synthesizing a hydrogel comprising poly(N-isopropylacrylamide) cross-linked hyaluronic acid, which comprises (a) synthesizing methacrylated hyaluronic acid; and (b) copolymerizing methacrylated hyaluronic acid with N-isopropylacrylamide.
摘要翻译: 本发明提供包含聚(N-异丙基丙烯酰胺)交联透明质酸的水凝胶。 本发明还提供一种合成包含聚(N-异丙基丙烯酰胺)交联透明质酸的水凝胶的方法,其包括(a)合成甲基丙烯酸酯化的透明质酸; 和(b)将甲基丙烯酸酯化的透明质酸与N-异丙基丙烯酰胺共聚。