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公开(公告)号：US20180002366A1
公开(公告)日：2018-01-04
申请号：US15685824
申请日：2017-08-24
IPC分类号： C07H19/14 , C07D487/04 , A61K31/7064 , A61K45/06 , C07H19/12 , C07H19/06
CPC分类号： C07H19/14 , A61K31/7064 , A61K45/06 , C07D487/04 , C07H19/06 , C07H19/12
摘要： The present invention is directed to 4′-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.
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公开(公告)号：US09777035B2
公开(公告)日：2017-10-03
申请号：US14669398
申请日：2015-03-26
IPC分类号： A61K31/7064 , A61K45/06 , C07H19/12 , C07H19/14 , C07H19/06 , C07D487/04
CPC分类号： C07H19/14 , A61K31/7064 , A61K45/06 , C07D487/04 , C07H19/06 , C07H19/12
摘要： The present invention is directed to 4′-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.
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公开(公告)号：US20150274767A1
公开(公告)日：2015-10-01
申请号：US14669398
申请日：2015-03-26
IPC分类号： C07H19/14 , C07H19/12 , A61K45/06 , A61K31/7064
CPC分类号： C07H19/14 , A61K31/7064 , A61K45/06 , C07D487/04 , C07H19/06 , C07H19/12
摘要： The present invention is directed to 4′-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.
摘要翻译： 本发明涉及式I的4'-取代的核苷衍生物及其用于抑制HIV逆转录酶，HIV预防感染，HIV感染治疗以及预防，治疗和延迟的用途 AIDS和/或ARC的发病或进展。
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