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公开(公告)号:US09808445B2
公开(公告)日:2017-11-07
申请号:US15303322
申请日:2015-04-10
发明人: Isao Sakurada , Tomokazu Hirabayashi , Yoshitaka Maeda , Hiroshi Nagasue , Takashi Mizuno , Jiayi Xu , Ting Zhang , Cameron Smith , Dann Parker
IPC分类号: A61K31/501 , A61K31/439 , C07D413/14 , C07D261/20 , C07D413/04 , C07D498/04 , C07D209/52 , C07D519/00 , A61K31/444 , A61K31/506 , A61K45/06
CPC分类号: A61K31/439 , A61K31/444 , A61K31/501 , A61K31/506 , A61K45/06 , C07D209/52 , C07D261/20 , C07D413/04 , C07D413/14 , C07D498/04 , C07D519/00
摘要: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
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公开(公告)号:US20170027916A1
公开(公告)日:2017-02-02
申请号:US15303322
申请日:2015-04-10
发明人: Isao Sakurada , Tomokazu Hirabayashi , Yoshitaka Maeda , Hiroshi Nagasue , Takashi Mizuno , Jiayi Xu , Ting Zhang , Cameron Smith , Dann Parker
IPC分类号: A61K31/439 , A61K45/06 , A61K31/444 , A61K31/506 , A61K31/501 , C07D519/00 , C07D413/14 , C07D498/04
CPC分类号: A61K31/439 , A61K31/444 , A61K31/501 , A61K31/506 , A61K45/06 , C07D209/52 , C07D261/20 , C07D413/04 , C07D413/14 , C07D498/04 , C07D519/00
摘要: In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
摘要翻译: 在其许多实施方案中,本发明提供了由式(I)表示的新一类苯甲酰胺化合物或其药学上可接受的盐或溶剂化物,或包含一种或多种所述化合物或其药学上可接受的盐或溶剂化物的药物组合物,以及使用 所述化合物或其药学上可接受的盐或溶剂合物用于治疗或预防血栓形成,栓塞,高凝状态或纤维变性。
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