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1.发明申请MATERIALS AND METHODS FOR CONTROLLING VASCULOGENESIS FROM ENDOTHELIAL COLONY FORMING CELLS 审中-公开从内皮细胞形成细胞中控制血管生成的材料和方法公开(公告)号：US20140193473A1
公开(公告)日：2014-07-10
申请号：US14123483
申请日：2012-06-06
CPC分类号： A61K35/51 , A61K9/70 , A61L27/24 , A61L27/3808
摘要： Materials and methods are disclosed for controlling vasculogenesis using building blocks of a collagen matrix and endothelial colony forming cells (ECFC). The building blocks may be isolated by fractionating an acid soluble Type I collagen. The building blocks comprising monomers and/or oligomers may be recombined in desired ratios to alter the matrix microenvironment and to influence ECFC behavior.
摘要翻译： 公开了使用胶原基质和内皮细胞集落形成细胞（ECFC）的构建块控制血管发生的材料和方法。 可以通过分解酸溶性I型胶原来分离构建块。 包含单体和/或低聚物的结构单元可以以所需比例重组以改变基质微环境并影响ECFC行为。
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公开(公告)号：US09867905B2
公开(公告)日：2018-01-16
申请号：US12332084
申请日：2008-12-10
CPC分类号： A61L27/507 , A61L27/24 , A61L27/3808 , A61L27/3834
摘要： Collagen based-matrices and methods of their use are described. More particularly, collagen-based matrices for differentiating stem cells and progenitor cells, and for producing and isolating blood vessels and vascularized graft constructs are described.
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公开(公告)号：US20090280180A1
公开(公告)日：2009-11-12
申请号：US12332084
申请日：2008-12-10
CPC分类号： A61L27/507 , A61L27/24 , A61L27/3808 , A61L27/3834
摘要： Collagen based-matrices and methods of their use are described. More particularly, collagen-based matrices for differentiating stem cells and progenitor cells, and for producing and isolating blood vessels and vascularized graft constructs are described.
摘要翻译： 描述了基于胶原的基质及其使用方法。 更具体地，描述了用于分化干细胞和祖细胞以及用于产生和分离血管和血管化移植物构建体的基于胶原的基质。
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公开(公告)号：US06521225B1
公开(公告)日：2003-02-18
申请号：US08921497
申请日：1997-09-02
申请人： Arun Srivastava , Selvarangan Ponnazhagan , Robert H. Chloemer , Xu-Shan Wang , Mervin C. Yoder , Shang-Zhen Zhou , Jaime Escobedo , Varavani Dwarki
发明人： Arun Srivastava , Selvarangan Ponnazhagan , Robert H. Chloemer , Xu-Shan Wang , Mervin C. Yoder , Shang-Zhen Zhou , Jaime Escobedo , Varavani Dwarki
IPC分类号： A61K3500
CPC分类号： C12N15/86 , A61K48/00 , C07K14/705 , C12N2750/14143
摘要： The present invention is directed to a recombinant adenovirus vector comprising two inverted terminal repeats (ITRs) each of which comprises a D-sequence having (i) from 5 to 15 native nucleotides and (ii) one or more deletions or substitutions therein.
摘要翻译： 本发明涉及包含两个反向末端重复序列（ITR）的重组腺病毒载体，每个重复序列包含具有（i）5至15个天然核苷酸的D序列和（ii）其中一个或多个缺失或替换。
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