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公开(公告)号：US20170169283A1
公开(公告)日：2017-06-15
申请号：US15081987
申请日：2016-03-28
发明人： Yen-Chun Chen , Ming-Hui Cheng , Yu-Fen Kuo , Po-Wei Pan , Tsung-Chih Yu
IPC分类号： G06K9/00 , G06T7/40 , G06T7/00 , G01N33/483
CPC分类号： G06K9/00147 , G01N33/483 , G01N2333/025 , G06K9/0014 , G06K9/48 , G06K2009/485 , G06T7/0012 , G06T7/12 , G06T7/13 , G06T7/90 , G06T2207/10024 , G06T2207/20084 , G06T2207/30004 , G06T2207/30024
摘要： The present invention discloses a method for detecting whether cells are infected with human papillomavirus (HPV), and the method includes: (a) capturing a contour of a cell of a cell image, wherein the contour has a contour pixel thereon; (b) identifying a tangent of the contour pixel on the contour to define in relation to the tangent a first side and a second side opposite to the first side, wherein the first side indicates the intracellular region of the cell and the second side indicates the extracellular region of the cell; (c) calculating an optical parameter average of the plurality of pixels on both of the first side and the second side; and (d) determining whether the cell is infected with HPV based on whether the optical parameter average on the first side is smaller than that on the second side.
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公开(公告)号：US10402623B2
公开(公告)日：2019-09-03
申请号：US15826700
申请日：2017-11-30
发明人： Jia-Hong Zhang , Yan-Jun Chen , Yu-Fen Kuo
摘要： A large scale cell image analysis method and system are provided. The method includes: obtaining a cell image; performing a region segmentation process; and performing a feature calculation process. The region segmentation process includes: performing a statistical intensity algorithm according to the cell image to calculate a first threshold and a second threshold; dividing the cell image into a background region and a cell region according to the first threshold; performing an average intensity process according to the cell region to calculate a third threshold and a fourth threshold; and dividing the cell region into a cytoplasmic region and a nucleus region according to the third threshold and the fourth threshold. The feature calculation process calculates at least one feature at least according to the cell region, the nucleus region, and the cytoplasmic region.
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公开(公告)号：US09953208B2
公开(公告)日：2018-04-24
申请号：US15081987
申请日：2016-03-28
发明人： Yen-Chun Chen , Ming-Hui Cheng , Yu-Fen Kuo , Po-Wei Pan , Tsung-Chih Yu
IPC分类号： G06K9/00 , G01N33/483 , G06T7/00 , G06T7/40
CPC分类号： G06K9/00147 , G01N33/483 , G01N2333/025 , G06K9/0014 , G06K9/48 , G06K2009/485 , G06T7/0012 , G06T7/12 , G06T7/13 , G06T7/90 , G06T2207/10024 , G06T2207/20084 , G06T2207/30004 , G06T2207/30024
摘要： The present invention discloses a method for detecting whether cells are infected with human papillomavirus (HPV), and the method includes: (a) capturing a contour of a cell of a cell image, wherein the contour has a contour pixel thereon; (b) identifying a tangent of the contour pixel on the contour to define in relation to the tangent a first side and a second side opposite to the first side, wherein the first side indicates the intracellular region of the cell and the second side indicates the extracellular region of the cell; (c) calculating an optical parameter average of the plurality of pixels on both of the first side and the second side; and (d) determining whether the cell is infected with HPV based on whether the optical parameter average on the first side is smaller than that on the second side.
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