公开(公告)号：US06937906B2

公开(公告)日：2005-08-30

申请号：US10059599

申请日：2002-01-29

申请人： Michael B. Terry ,  James D. Reinke ,  Ron Kalin

发明人： Michael B. Terry ,  James D. Reinke ,  Ron Kalin

IPC分类号： A61N1/08 ,  A61N1/37 ,  G01R29/08

CPC分类号： G01R29/0814 ,  A61N1/08 ,  A61N1/3718

摘要： The present invention provides a method and apparatus for detecting magnetic fields in implantable medical devices. The apparatus includes a sensor adapted to provide at least one signal proportional to at least one vector component of a magnetic field. The apparatus further includes a circuit adapted to receive the signal and perform a predetermined action when a predetermined quantity exceeds a predetermined threshold value.

摘要翻译： 本发明提供一种用于检测可植入医疗装置中的磁场的方法和装置。 该装置包括适于提供与磁场的至少一个矢量分量成比例的至少一个信号的传感器。 该装置还包括适于在预定量超过预定阈值时接收信号并执行预定动作的电路。

公开(公告)号：US06944489B2

公开(公告)日：2005-09-13

申请号：US10059512

申请日：2002-01-29

申请人： Volkert A. Zeijlemaker ,  Ron Kalin ,  Gregory A. Hrdlicka ,  Yong Kyun Cho ,  James D. Reinke ,  Laurie D. Foerster

发明人： Volkert A. Zeijlemaker ,  Ron Kalin ,  Gregory A. Hrdlicka ,  Yong Kyun Cho ,  James D. Reinke ,  Laurie D. Foerster

IPC分类号： A61N20060101 ,  A61N1/05 ,  A61N1/362 ,  A61N1/372 ,  A61N1/39 ,  A61B5/04

CPC分类号： A61N1/056 ,  A61N1/086 ,  A61N1/3718

摘要： An electrical lead includes an elongate body having a proximal end portion and a distal end portion, a first electrode disposed adjacent and joined to the distal end portion of the elongate body. Current flow within the first electrode is limited when a predetermined condition occurs, such as the generation of an electromagnetic field having a predetermined frequency range. The medical electrical lead may further comprise one or more second electrodes disposed adjacent the first electrode and joined to the elongate body to shunt current to body tissue when the predetermined condition occurs.

摘要翻译： 电引线包括具有近端部分和远端部分的细长主体，与细长主体的远端部分相邻并连接的第一电极。 当预定条件发生时，例如产生具有预定频率范围的电磁场，第一电极内的电流被限制。 医疗电引线还可以包括一个或多个第二电极，其邻近第一电极设置并连接到细长主体，以在发生预定条件时将电流分流到身体组织。

公开(公告)号：US06985775B2

公开(公告)日：2006-01-10

申请号：US10059601

申请日：2002-01-29

申请人： James D. Reinke ,  Jeffrey D. Wilkinson ,  Ron Kalin ,  Laurie D. Foerster ,  Volkert A. Zeijlemaker

发明人： James D. Reinke ,  Jeffrey D. Wilkinson ,  Ron Kalin ,  Laurie D. Foerster ,  Volkert A. Zeijlemaker

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/086 ,  A61N1/3718

摘要： An electrical lead end cap includes a body defining a bore therein capable of receiving and retaining an end of an electrical lead and a connector capable of electrically coupling conductors leading to at least two electrodes. A method includes routing an electrical current induced in an electrical lead conductor disposed within body tissue to a plurality of electrodes, electrically coupled with the body tissue, via a circuit within an end cap attached to the electrical lead.

公开(公告)号：US07076283B2

公开(公告)日：2006-07-11

申请号：US10004237

申请日：2001-10-31

申请人： Yong Kyun Cho ,  Ron Kalin ,  James D. Reinke

发明人： Yong Kyun Cho ,  Ron Kalin ,  James D. Reinke

IPC分类号： A61B5/05

CPC分类号： A61N1/3702 ,  A61N1/36514 ,  A61N1/3718 ,  Y10S128/901

摘要： A method is provided, the method comprising detecting a magnetic resonance imaging (MRI) interference signal and enabling at least one preventive measure to protect an implantable medical device from interference by the magnetic resonance imaging (MRI) interference signal. The method also comprises switching from a first sensing mode more affected by the magnetic resonance imaging (MRI) interference signal to a second sensing mode less affected by the magnetic resonance imaging (MRI) interference signal.

摘要翻译： 提供了一种方法，所述方法包括检测磁共振成像（MRI）干扰信号，并且使至少一种预防措施能够保护可植入医疗装置免受磁共振成像（MRI）干扰信号的干扰。 该方法还包括从受磁共振成像（MRI）干扰信号更多影响的第一感测模式切换到较少受到磁共振成像（MRI）干扰信号影响的第二感测模式。

公开(公告)号：US07050855B2

公开(公告)日：2006-05-23

申请号：US10059589

申请日：2002-01-29

申请人： Volkert A. Zeijlemaker ,  Ron Kalin ,  Gregory A. Hrdlicka ,  Yong Kyun Cho ,  James D. Reinke ,  Laurie D. Foerster

发明人： Volkert A. Zeijlemaker ,  Ron Kalin ,  Gregory A. Hrdlicka ,  Yong Kyun Cho ,  James D. Reinke ,  Laurie D. Foerster

IPC分类号： A61N1/37

CPC分类号： A61N1/37 ,  A61B90/04 ,  A61B2090/0418 ,  A61B2090/0481 ,  A61B2090/3954 ,  A61N1/365 ,  A61N1/36514 ,  A61N1/3718

摘要： Apparatus and methods are disclosed for reducing the potentially harmful effects of electromagnetic waves on an implantable medical device. In one embodiment of the present invention, an implantable medical system comprising a dual threshold magnetic sensor capable of detecting an elevated magnetic field is disclosed. The sensor can comprise a solid-state sensor capable of detecting a static magnetic field in excess of about 1500 Gauss. The magnetic sensor can be operatively coupled to electronics that are capable of altering the operation of the system upon detection of an elevated magnetic field by the magnetic sensor.

公开(公告)号：US09958351B2

公开(公告)日：2018-05-01

申请号：US13428108

申请日：2012-03-23

申请人： Jonathan L. Kuhn ,  Richard J. O'Brien ,  Jonathan P. Roberts ,  James D. Reinke ,  Michael B. Terry ,  Kamal Deep Mothilal

发明人： Jonathan L. Kuhn ,  Richard J. O'Brien ,  Jonathan P. Roberts ,  James D. Reinke ,  Michael B. Terry ,  Kamal Deep Mothilal

IPC分类号： G01L9/12 ,  G01L19/02 ,  A61B5/00 ,  A61B5/03 ,  G01L19/14 ,  G01L15/00 ,  A61B5/0215 ,  A61B5/20

CPC分类号： G01L9/125 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/031 ,  A61B5/036 ,  A61B5/205 ,  A61B5/42 ,  G01L15/00 ,  G01L19/02 ,  G01L19/149

摘要： A pressure sensing system provides signals representative of a magnitude of pressure at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A calculated pressure, a bending pressure error and a bend-compensated pressure are computed in response to the first signal and the second signal.

公开(公告)号：US20120245864A1

公开(公告)日：2012-09-27

申请号：US13428108

申请日：2012-03-23

申请人： Jonathan L. Kuhn ,  Richard J. O'Brien ,  Jonathan P. Roberts ,  James D. Reinke ,  Michael B. Terry ,  Kamal Deep Mothilal

发明人： Jonathan L. Kuhn ,  Richard J. O'Brien ,  Jonathan P. Roberts ,  James D. Reinke ,  Michael B. Terry ,  Kamal Deep Mothilal

IPC分类号： G06F19/00

CPC分类号： G01L9/125 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/031 ,  A61B5/036 ,  A61B5/205 ,  A61B5/42 ,  G01L15/00 ,  G01L19/02 ,  G01L19/149

摘要： A pressure sensing system provides signals representative of a magnitude of pressure at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A calculated pressure, a bending pressure error and a bend-compensated pressure are computed in response to the first signal and the second signal.

摘要翻译： 压力感测系统提供表示选定部位压力大小的信号。 传感器模块包括第一传感器，其产生具有对施加到传感器模块的压力和应变的相关联的第一响应的第一信号，以及产生具有对施加到传感器模块的压力和应变的相关联的第二响应的第二信号的第二传感器。 响应于第一信号和第二信号计算计算压力，弯曲压力误差和弯曲补偿压力。

公开(公告)号：US08155758B2

公开(公告)日：2012-04-10

申请号：US11380567

申请日：2006-04-27

申请人： Glenn M. Roline ,  Michael B. Terry ,  Jonathan P. Roberts ,  James D. Reinke ,  Robert A. Corey

发明人： Glenn M. Roline ,  Michael B. Terry ,  Jonathan P. Roberts ,  James D. Reinke ,  Robert A. Corey

IPC分类号： A61N1/37

CPC分类号： A61N1/36564 ,  A61N1/3605 ,  A61N1/36514 ,  A61N1/36557 ,  A61N2001/083

摘要： This disclosure relates to fault tolerant instantiations of a cardiac therapy delivery device such as an implantable cardiac stimulator (e.g., an implantable pulse generator, IPG, and/or an implantable cardioverter-defibrillator, ICD) coupled to an implantable physiologic sensor (IPS). According to the disclosure delivery of cardiac pacing and/or cardioversion-defibrillator therapy delivery can cause errors in output signals from an IPS. Resolution of such errors involves selectively energizing (or disconnecting the output signal from) the IPS during pacing and/or defibrillation therapy delivery. Programmable signal “blanking” in lieu of or in addition to the foregoing also improves the integrity of the output signal (i.e., continuously energize the IPS and ignore parts of the output signal). An ICD having a transient weakness in an insulated conductor used for the IPS signal can likewise have the IPS de-energized and/or blank the IPS output signal during high voltage therapy delivery.

摘要翻译： 本公开涉及心脏治疗递送装置的容错实例，例如可植入的心脏刺激器（例如，可植入脉冲发生器，IPG和/或植入式心律转复除颤器，ICD），其与可植入生理传感器（IPS）耦合。 根据心脏起搏和/或心脏复律 - 除颤器治疗传递的披露递送可能导致来自IPS的输出信号的错误。 这种错误的解决涉及在起搏和/或除颤治疗递送期间选择性地激励（或断开输出信号）IPS。 代替或除了上述之外的可编程信号“消隐”还提高了输出信号的完整性（即，连续地激励IPS并忽略输出信号的部分）。 在IPS信号中使用的绝缘导体具有瞬时弱点的ICD同样可以在高电压治疗传送期间使IPS不通电和/或空白IPS输出信号。

公开(公告)号：US08396563B2

公开(公告)日：2013-03-12

申请号：US12697070

申请日：2010-01-29

申请人： James D. Reinke ,  Robert M. Ecker ,  Kaustubh R. Patil ,  Michael B. Terry ,  Jonathan P. Roberts ,  Robert A. Corey

发明人： James D. Reinke ,  Robert M. Ecker ,  Kaustubh R. Patil ,  Michael B. Terry ,  Jonathan P. Roberts ,  Robert A. Corey

IPC分类号： A61N1/36 ,  A61N1/378

CPC分类号： G06F1/12 ,  A61N1/37288 ,  G06F1/06

摘要： This disclosure is directed to the synchronization of clocks of a secondary implantable medical device (IMD) to a clock of a primary IMD. The secondary IMD includes a communications clock. The communications clock may be synchronized based on at least one received communications pulse. The secondary IMD further includes a general purpose clock different than the communications clock. The general purpose clock may be synchronized based on at least one received power pulse. The communications clock may also be synchronized based on the at least one received power pulse.

摘要翻译： 本公开涉及二次可植入医疗装置（IMD）的时钟与主IMD的时钟的同步。 辅助IMD包括通信时钟。 通信时钟可以基于至少一个接收到的通信脉冲来同步。 次级IMD还包括与通信时钟不同的通用时钟。 可以基于至少一个接收的功率脉冲同步通用时钟。 通信时钟也可以基于至少一个接收的功率脉冲来同步。

公开(公告)号：US20120245489A1

公开(公告)日：2012-09-27

申请号：US13176018

申请日：2011-07-05

申请人： Jonathan L. Kuhn ,  Jonathan P. Roberts ,  James D. Reinke ,  Richard J. O'Brien ,  Michael B. Terry ,  Kamal Deep Mothilal

发明人： Jonathan L. Kuhn ,  Jonathan P. Roberts ,  James D. Reinke ,  Richard J. O'Brien ,  Michael B. Terry ,  Kamal Deep Mothilal

IPC分类号： A61B5/103

CPC分类号： G01L9/125 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/031 ,  A61B5/036 ,  A61B5/205 ,  A61B5/42 ,  G01L15/00 ,  G01L19/02 ,  G01L19/149

摘要： An implantable medical sensor system provides signals representative of a magnitude of moment fraction applied to a sensor module at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A moment fraction is computed in response to the first signal and the second signal. In various embodiments, the moment fraction is used to guide positioning of the sensor module, indicate a need for repositioning the sensor module, report loading of the sensor module during normal operation for use as sensor design information and in setting sensor calibration ranges.

摘要翻译： 可植入医疗传感器系统提供表示在所选位置处施加到传感器模块的力矩分数的大小的信号。 传感器模块包括第一传感器，其产生具有对施加到传感器模块的压力和应变的相关联的第一响应的第一信号，以及产生具有对施加到传感器模块的压力和应变的相关联的第二响应的第二信号的第二传感器。 响应于第一信号和第二信号计算力矩分数。 在各种实施例中，力矩分数用于引导传感器模块的定位，指示需要重新定位传感器模块，在正常操作期间报告传感器模块的负载，以用作传感器设计信息和设置传感器校准范围。