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公开(公告)号：US09968788B2
公开(公告)日：2018-05-15
申请号：US12361977
申请日：2009-01-29
申请人： Robert Michael Ecker , Kaustubh R. Patil , John Robert Hamilton , James D. Reinke , Timothy Davis
发明人： Robert Michael Ecker , Kaustubh R. Patil , John Robert Hamilton , James D. Reinke , Timothy Davis
IPC分类号： A61B5/00 , A61N1/365 , A61B5/02 , A61B5/145 , A61B5/1459
CPC分类号： A61N1/36585 , A61B5/02028 , A61B5/14542 , A61B5/1459 , A61B5/7203
摘要： In general, the disclosure is directed toward an implantable medical device that includes a plurality of sensor modules that are implanted within a patient. The sensor modules may cooperate with each other to coordinate the timing for performance of one or more sensor actions across the modules when making a measurement. Example measurements include tissue perfusion measurements, oxygen sensing measurements, sonomicrometry measurements, and pressure measurements. The coordination of the sensor modules may be controlled by a signal that is transmitted from a host controller to the sensor modules via a bus. In some examples, the bus may have two wires that transmit both timing information and data information to the sensor modules. The signal may be a signal that is substantially periodic, such as a pulsed signal. In additional examples, the signal may supply operating power and timing information to the sensor modules.
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公开(公告)号：US08774918B2
公开(公告)日：2014-07-08
申请号：US12362838
申请日：2009-01-30
申请人： William T. Donofrio , John E. Burnes , Paul G. Krause , Xiaohong Zhou , Gerald P. Arne , David J. Peichel , James D. Reinke
发明人： William T. Donofrio , John E. Burnes , Paul G. Krause , Xiaohong Zhou , Gerald P. Arne , David J. Peichel , James D. Reinke
CPC分类号： A61N1/3621 , A61B5/04288 , A61B5/7217 , A61N1/025 , A61N1/0551 , A61N1/36185 , A61N1/3686 , A61N1/3702 , A61N1/3706 , A61N1/3718 , A61N1/37247 , A61N1/37288 , A61N1/3962
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.
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公开(公告)号：US08688210B2
公开(公告)日：2014-04-01
申请号：US12362859
申请日：2009-01-30
申请人： John E. Burnes , Paul G. Krause , William T. Donofrio , Gerald P. Arne , David J. Peichel , Xiaohong Zhou , James D. Reinke
发明人： John E. Burnes , Paul G. Krause , William T. Donofrio , Gerald P. Arne , David J. Peichel , Xiaohong Zhou , James D. Reinke
IPC分类号： A61N1/08
CPC分类号： A61N1/36114 , A61B5/0424 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7217 , A61B2560/0271 , A61N1/36185 , A61N1/3622 , A61N1/365 , A61N1/3686 , A61N1/37247 , A61N1/37288 , A61N1/3962 , A61N2001/083
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.
摘要翻译： 可以评估两个可植入医疗装置或两个不同的可植入医疗装置的不同治疗模块之间的电串扰，并且在一些示例中可以减轻。 在一些示例中，可植入医疗装置或治疗模块之一将电刺激递送至非心肌组织部位或非血管心脏组织部位，而另一种可植入医疗装置或治疗组件将心律管理治疗递送至患者的心脏。
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公开(公告)号：US20120245864A1
公开(公告)日：2012-09-27
申请号：US13428108
申请日：2012-03-23
申请人： Jonathan L. Kuhn , Richard J. O'Brien , Jonathan P. Roberts , James D. Reinke , Michael B. Terry , Kamal Deep Mothilal
发明人： Jonathan L. Kuhn , Richard J. O'Brien , Jonathan P. Roberts , James D. Reinke , Michael B. Terry , Kamal Deep Mothilal
IPC分类号： G06F19/00
CPC分类号： G01L9/125 , A61B5/00 , A61B5/0215 , A61B5/031 , A61B5/036 , A61B5/205 , A61B5/42 , G01L15/00 , G01L19/02 , G01L19/149
摘要： A pressure sensing system provides signals representative of a magnitude of pressure at a selected site. A sensor module includes a first transducer producing a first signal having an associated first response to pressure and strain applied to the sensor module and a second transducer producing a second signal having an associated second response to pressure and strain applied to the sensor module. A calculated pressure, a bending pressure error and a bend-compensated pressure are computed in response to the first signal and the second signal.
摘要翻译： 压力感测系统提供表示选定部位压力大小的信号。 传感器模块包括第一传感器，其产生具有对施加到传感器模块的压力和应变的相关联的第一响应的第一信号，以及产生具有对施加到传感器模块的压力和应变的相关联的第二响应的第二信号的第二传感器。 响应于第一信号和第二信号计算计算压力，弯曲压力误差和弯曲补偿压力。
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公开(公告)号：US08275435B2
公开(公告)日：2012-09-25
申请号：US12690957
申请日：2010-01-21
申请人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
发明人： Jonathan L. Kuhn , Jonathan P. Roberts , Andrew J. Ries , James D. Reinke , Jeffrey M. Jelen , Robert M. Ecker , Timothy J. Davis , Can Cinbis , Thomas A. Anderson
IPC分类号： A61B5/00
CPC分类号： A61B5/1459 , A61B5/14542 , A61B5/1495 , A61B2562/0233 , A61B2562/046 , A61N1/36557 , G06F19/00 , G16H40/63
摘要： An implantable medical device having an optical sensor selects the function of modular opto-electronic assemblies included in the optical sensor. Each assembly is provided with at least one light emitting device and at least one light detecting device. A device controller coupled to the optical sensor controls the function of each the assemblies. The controller executes a sensor performance test and selects at least one of the plurality of assemblies to operate as a light emitting assembly in response to a result of the performance test. The controller selects at least one other of the plurality of optical sensor assemblies to operate as a light detecting assembly in response to a result of the performance test.
摘要翻译： 具有光学传感器的可植入医疗装置选择包括在光学传感器中的模块化光电组件的功能。 每个组件设置有至少一个发光装置和至少一个光检测装置。 耦合到光学传感器的设备控制器控制每个组件的功能。 控制器执行传感器性能测试，并且响应于性能测试的结果，选择多个组件中的至少一个作为发光组件进行操作。 响应于性能测试的结果，控制器选择多个光学传感器组件中的至少一个以作为光检测组件进行操作。
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公开(公告)号：US08265771B2
公开(公告)日：2012-09-11
申请号：US12610025
申请日：2009-10-30
申请人： William T. Donofrio , Paul Gordon Krause , Gerald P. Arne , James D. Reinke , David Jerome Peichel , Timothy Davis , John E. Burnes
发明人： William T. Donofrio , Paul Gordon Krause , Gerald P. Arne , James D. Reinke , David Jerome Peichel , Timothy Davis , John E. Burnes
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61N1/3718 , A61N1/3787 , H02M1/44
摘要： A therapy or monitoring system may implement one or more techniques to mitigate interference between operation of a charging device that charges a first implantable medical device (IMD) implanted in a patient and a second IMD implanted in the patient. In some examples, the techniques may include modifying an operating parameter of the charging device in response to receiving an indication that a second IMD is implanted in the patient. The techniques also may include modifying an operating parameter of the second IMD in response to detecting the presence or operation of the charging device.
摘要翻译： 治疗或监测系统可以实施一种或多种技术，以减轻对植入患者中的第一可植入医疗装置（IMD）充电的充电装置的操作与植入患者体内的第二IMD之间的干扰。 在一些示例中，技术可以包括响应于接收到将第二IMD植入患者中的指示来修改充电装置的操作参数。 这些技术还可以包括响应于检测到充电装置的存在或操作来修改第二IMD的操作参数。
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7.发明授权Fault tolerant implantable pulse generators and implantable cardioverter-defibrillators incorporating physiologic sensors and methods for implementing fault tolerance in same 有权容错植入式脉冲发生器和植入式心律转复除颤器，其结合生理传感器和实现相同容错的方法公开(公告)号：US08155758B2
公开(公告)日：2012-04-10
申请号：US11380567
申请日：2006-04-27
IPC分类号： A61N1/37
CPC分类号： A61N1/36564 , A61N1/3605 , A61N1/36514 , A61N1/36557 , A61N2001/083
摘要： This disclosure relates to fault tolerant instantiations of a cardiac therapy delivery device such as an implantable cardiac stimulator (e.g., an implantable pulse generator, IPG, and/or an implantable cardioverter-defibrillator, ICD) coupled to an implantable physiologic sensor (IPS). According to the disclosure delivery of cardiac pacing and/or cardioversion-defibrillator therapy delivery can cause errors in output signals from an IPS. Resolution of such errors involves selectively energizing (or disconnecting the output signal from) the IPS during pacing and/or defibrillation therapy delivery. Programmable signal “blanking” in lieu of or in addition to the foregoing also improves the integrity of the output signal (i.e., continuously energize the IPS and ignore parts of the output signal). An ICD having a transient weakness in an insulated conductor used for the IPS signal can likewise have the IPS de-energized and/or blank the IPS output signal during high voltage therapy delivery.
摘要翻译： 本公开涉及心脏治疗递送装置的容错实例，例如可植入的心脏刺激器（例如，可植入脉冲发生器，IPG和/或植入式心律转复除颤器，ICD），其与可植入生理传感器（IPS）耦合。 根据心脏起搏和/或心脏复律 - 除颤器治疗传递的披露递送可能导致来自IPS的输出信号的错误。 这种错误的解决涉及在起搏和/或除颤治疗递送期间选择性地激励（或断开输出信号）IPS。 代替或除了上述之外的可编程信号“消隐”还提高了输出信号的完整性（即，连续地激励IPS并忽略输出信号的部分）。 在IPS信号中使用的绝缘导体具有瞬时弱点的ICD同样可以在高电压治疗传送期间使IPS不通电和/或空白IPS输出信号。
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公开(公告)号：US08005551B2
公开(公告)日：2011-08-23
申请号：US12350382
申请日：2009-01-08
IPC分类号： A61N1/00
CPC分类号： A61N1/36514 , A61B5/02055 , A61B5/145 , A61B5/14532 , A61N1/05 , A61N1/056
摘要： An implantable medical lead includes a device, such as a physiological sensor, that is coupled to one or more stimulation/sensing sensing conductors within the lead. When the implantable medical lead is coupled to an implantable medical device, the device carried by the lead both receives power from, and communicates with the implantable medical device via the one or more stimulation/sensing sensing conductors. Each of the one or more stimulation/sensing sensing conductors is also coupled to an electrode that is exposed to body tissue.
摘要翻译： 可植入医疗引线包括耦合到引线内的一个或多个刺激/感测感测导体的装置，例如生理传感器。 当可植入医疗引线连接到可植入医疗设备时，由引线承载的设备都经由一个或多个刺激/感测感测导体从可植入医疗设备接收电力并与可植入医疗设备进行通信。 一个或多个刺激/感测感测导体中的每一个还耦合到暴露于身体组织的电极。
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公开(公告)号：US07935935B2
公开(公告)日：2011-05-03
申请号：US12394179
申请日：2009-02-27
IPC分类号： G01J1/42
CPC分类号： A61N1/372 , A61N1/025 , A61N1/3702 , A61N1/37276 , G04F5/16
摘要： A radiation-based timer for use in an implantable medical device (IMD) includes a radiation source and a radiation detection circuit. The radiation source emits radiation particles during a process referred to as radioactive decay. The radiation detection circuit detects the radiation particles emitted during the decay process and tracks the number of radiation particles detected. When the number of radiation particles detected reaches a threshold value, a timer signal is generated. In this manner, the radiation-based timer generates a timer signal as a function of the radioactive decay of the radiation source. The timer signal may be used by one or more components of the IMD for any of a number of functions, including as a wakeup trigger for a communications and/or a sensor event.
摘要翻译： 用于可植入医疗装置（IMD）的基于辐射的定时器包括辐射源和放射线检测电路。 辐射源在被称为放射性衰变的过程中发射辐射粒子。 辐射检测电路检测在衰变过程中发射的辐射粒子，并跟踪检测到的辐射粒子的数量。 当检测到的辐射粒子的数量达到阈值时，产生定时器信号。 以这种方式，基于辐射的定时器产生作为辐射源的放射性衰减的函数的定时器信号。 定时器信号可以由IMD的一个或多个组件用于多个功能中的任何一个，包括用于通信和/或传感器事件的唤醒触发。
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公开(公告)号：US20100114224A1
公开(公告)日：2010-05-06
申请号：US12362822
申请日：2009-01-30
申请人： Paul G. Krause , John E. Burnes , William T. Donofrio , David J. Peichel , Gerald P. Arne , Xiaohong Zhou , James D. Reinke
发明人： Paul G. Krause , John E. Burnes , William T. Donofrio , David J. Peichel , Gerald P. Arne , Xiaohong Zhou , James D. Reinke
CPC分类号： A61N1/37 , A61N1/3605 , A61N1/36114 , A61N1/36521 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.
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