摘要:
21-Cyclic acetals of steroids of the corticoid series are prepared from the corresponding 21-hydroxy steroids. The products have utility as anti-inflammatory agents.
摘要:
21-ACETALS AND MIXED ACETALS OF STEROIDS OF THE CORTICOID SERIES ARE PREPARED FROM THE CORRESPONDING 21-HYDROXY STEROIDS AND HAVE UTILITY AS ANTI-INFLAMMATORY AGENTS.
摘要:
21-Esters of 21-aldehyde hydrates and 21-aldehyde hemiacetals of steroids of the corticoid series are prepared from the corresponding 21-hydroxy steroids and have utility as antiinflammatory agents.
摘要:
A deck leverage anchor for securing an external device has an anchor body that is positioned at least partially within an opening of the deck so that a notch receives the edge of the surface. The anchor body comprises a swivel coupler that extends outward from the opening. The swivel coupler couples to an external device. A swivel plate is disposed opposite the swivel coupler to engage and distribute a load on the surface of the deck opposite the coupler.
摘要:
A hydraulic system comprises a pump having a fluid feed and a fluid release. Hydraulic actuator has an advance port and a retract port. A directional converter is fluidically coupled between the pump and the hydraulic actuator. The converter has a housing having a plurality of fluid passages therethrough. The plurality of fluid passages terminates in a pump outlet port, a pump inlet port, a first actuator port, and a second actuator port. The pump outlet port is coupled to the fluid release of the pump. The pump inlet port is fluidically coupled to the fluid feed of the pump. The first actuator port and second actuator port are respectively coupled to the advance port and the retract port of the actuator. A plurality of valves is disposed within the fluid passages. The plurality of valves has a first position and a second position. In the first position, a fluid flow direction at the first actuator port is into said housing from the actuator and a second fluid direction and a second actuator port is out of the housing. When the switches are in a second position the fluid flow direction is out of the housing at the second actuator port.
摘要:
Compounds of the formula ##STR1## wherein one of R.sup.1 and R.sup.2 is alkyl or the group ##STR2## IN WHICH N IS 0 TO 3 AND THE OTHER OF R.sup.1 and R.sup.2 is benzyl, substituted benzyl, phenyl or substituted phenyl, said substituted benzyl and substituted phenyl substituted on the phenyl ring with one or more substituents independently selected from the group consisting of halo, lower alkyl and trifluoromethyl; X and Y are independently oxygen or sulfur with the proviso that Y is not oxygen when R.sup.2 is phenyl or substituted phenyl; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.
摘要:
A deck leverage anchor for securing an external device has an anchor body that is positioned at least partially within an opening of the deck so that a notch receives the edge of the surface. The anchor body comprises a swivel coupler that extends outward from the opening. The swivel coupler couples to an external device. A swivel plate is disposed opposite the swivel coupler to engage and distribute a load on the surface of the deck opposite the coupler.
摘要:
Compounds useful in treating cardiovascular disorders are the carboxylic acids depicted in formulas (1) and (2) ##STR1## as well as their pharmaceutically acceptable, non-toxic salts and esters, wherein:n is an integer from one to four;R.sub.1 is hydroxy;R.sub.2 is hydrogen; orR.sub.1 and R.sub.2 together are an oxo group;R.sub.3 is ##STR2## wherein A is --CH.sub.2 --CH.sub.2 --; trans-CH.dbd.CH--; --C.tbd.C--; andR.sub.4 is linear or branched alkyl of one to twelve carbons, cycloalkyl of three to eight carbons; phenyl optionally substituted with one or two identical substituents selected from the group consisting of lower alkyl, lower alkoxy, hydroxy, trifluoromethyl, and halo; or optionally substituted phenylalkyl.
摘要:
22-Optionally substituted steroids of the corticoid series are prepared from the corresponding 21-methylene steroids through the 20,21-dione steroid intermediates. These compounds have utility as anti-inflammatory agents.
摘要:
Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently alkyl or the group ##STR2## IN WHICH N IS 0 TO 3; X and Y are independently oxygen or sulfur; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.