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1.发明授权Systems and methods related to optical nanosensors comprising photoluminescent nanostructures 有权涉及包含光致发光纳米结构的光学纳米传感器的系统和方法公开(公告)号：US08460608B2
公开(公告)日：2013-06-11
申请号：US12967563
申请日：2010-12-14
IPC分类号： G01N21/64
CPC分类号： G01N33/227 , B82Y30/00 , G01N21/6428 , G01N21/643 , G01N21/6489 , G01N2201/061 , G01N2201/068
摘要： Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described.
摘要翻译： 通常描述与包含光致发光纳米结构的光学纳米传感器有关的系统和方法。
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公开(公告)号：US09664677B2
公开(公告)日：2017-05-30
申请号：US13090199
申请日：2011-04-19
IPC分类号： G01N33/542 , B82Y30/00
CPC分类号： G01N33/542 , B82Y30/00
摘要： A composition can include a complex, where the complex includes a photoluminescent nanostructure and a polymer free from selective binding to an analyte, the polymer adsorbed on the photoluminescent nanostructure, and a selective binding site associated with the complex.
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公开(公告)号：US20110045523A1
公开(公告)日：2011-02-24
申请号：US12860752
申请日：2010-08-20
CPC分类号： G01N33/84 , B82Y15/00 , B82Y30/00 , G01N21/6428 , G01N21/6489 , G01N33/54346 , G01N33/54373 , G01N2021/6432 , G01N2021/7786 , Y10T436/177692
摘要： Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. Generally, the nanosensors comprise a photoluminescent nanostructure and a polymer that interacts with the photoluminescent nanostructure. In some cases, the interaction between the polymer and the nanostructure can be non-covalent (e.g., via van der Waals interactions). The nanosensors comprising a polymer and a photoluminescent nanostructure may be particularly useful in determining the presence and/or concentration of relatively small molecules, in some embodiments. In addition, in some instances the nanosensors may be capable of determining relatively low concentrations of analytes, in some cases determining as little as a single molecule. In some embodiments, the interaction between the analyte and the nanosensor (e.g., between the analyte and the photoluminescent nanostructure) can be reversible, which may allow, for example, for the reuse of a nanosensor after it has been exposed to an analyte.
摘要翻译： 通常描述与包含光致发光纳米结构的光学纳米传感器有关的系统和方法。 通常，纳米传感器包含光致发光纳米结构和与光致发光纳米结构相互作用的聚合物。 在一些情况下，聚合物和纳米结构之间的相互作用可以是非共价的（例如，通过范德华相互作用）。 在一些实施方案中，包含聚合物和光致发光纳米结构的纳米传感器可以特别用于确定相对较小分子的存在和/或浓度。 此外，在一些情况下，纳米传感器可能能够确定相对低浓度的分析物，在某些情况下确定与单个分子一样少。 在一些实施方案中，分析物和纳米传感器之间的相互作用（例如，分析物和光致发光纳米结构之间）之间的相互作用可以是可逆的，这可以允许例如纳米传感器暴露于分析物之后再利用。
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4.发明申请公开(公告)号：US20110257033A1
公开(公告)日：2011-10-20
申请号：US13090199
申请日：2011-04-19
CPC分类号： G01N33/542 , B82Y30/00
摘要： A composition can include a complex, where the complex includes a photoluminescent nanostructure and a polymer free from selective binding to an analyte, the polymer adsorbed on the photoluminescent nanostructure, and a selective binding site associated with the complex.
摘要翻译： 组合物可以包括络合物，其中复合物包括光致发光纳米结构和不与分析物选择性结合的聚合物，吸附在光致发光纳米结构上的聚合物和与络合物相关的选择性结合位点。
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5.发明授权公开(公告)号：US08377700B2
公开(公告)日：2013-02-19
申请号：US12659193
申请日：2010-02-26
申请人： Michael S. Strano , Paul W. Barone , Jin-Ho Ahn , Ardemis Anoush Boghossian , Rene Ortiz-Garcia , Hyeonseok Yoon , Jingqing Zhang
发明人： Michael S. Strano , Paul W. Barone , Jin-Ho Ahn , Ardemis Anoush Boghossian , Rene Ortiz-Garcia , Hyeonseok Yoon , Jingqing Zhang
CPC分类号： G01N33/582 , B82Y15/00 , G01N33/588 , Y10T436/143333 , Y10T436/144444
摘要： Systems and methods related to compositions including hydrogels and photoluminescent nanostructures are described. The compositions can undergo a change in a physical, chemical, dielectric, or other property upon exposure to an altering stimulus. Changes in one or more properties of the hydrogel may impart a change in the photoluminescence of the nanostructures embedded in the hydrogel.
摘要翻译： 描述与包括水凝胶和光致发光纳米结构的组合相关的系统和方法。 当暴露于改变刺激物时，组合物可以经历物理，化学，电介质或其它性质的变化。 水凝胶的一个或多个性质的变化可能使嵌入在水凝胶中的纳米结构的光致发光变化。
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