Novel quinuclidine derivatives and their pharmaceutical use
    8.
    发明申请
    Novel quinuclidine derivatives and their pharmaceutical use 失效
    新型奎宁环衍生物及其药物用途

    公开(公告)号:US20060217415A1

    公开(公告)日:2006-09-28

    申请号:US10568148

    申请日:2004-06-29

    IPC分类号: A61K31/4745 C07D453/02

    CPC分类号: C07D453/02

    摘要: This invention relates to novel quinuclidine derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

    摘要翻译: 本发明涉及新的奎宁环衍生物及其作为药物的用途。 由于其药理学特征,本发明的化合物可用于治疗与中枢神经系统(CNS),周围神经系统(PNS),疾病或病症相关的胆碱能系统相关的疾病或障碍 平滑肌肉收缩,内分泌疾病或病症,与神经变性相关的疾病或病症,与由化学物质的滥用终止引起的炎症,疼痛和戒断症状相关的疾病或病症。