公开(公告)号：US4926504A

公开(公告)日：1990-05-22

申请号：US197531

申请日：1988-05-23

申请人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto

发明人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto

IPC分类号： A47K13/20

CPC分类号： A47K13/20

摘要： A toilet seat structure capable of automatically feeding a seat covering paper onto the toilet seat is disclosed. Since the sheet paper feeding mechanism and a paper cutting mechanism operated by an electronic control unit. A specified length of paper appropriate for covering the toilet seat is automatically and accurately fed and positioned on the toilet seat. After use, the seat covering paper can automatically be cut off. For lavatories at public sites in particular, since the user can operate the apparatus to feed the paper from a functional casing to provide a new seat covering paper on the toilet seat for each use, the user can be assured of a clean toilet seat. Also, since the seat covering paper is held immovable on the toilet seat, the use of the paper covered toilet is made easier.

公开(公告)号：US4928325A

公开(公告)日：1990-05-29

申请号：US350419

申请日：1989-05-11

申请人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto

发明人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto

IPC分类号： A47K13/20

CPC分类号： A47K13/20

摘要： A toilet seat structure capable of automatically feeding a seat covering paper onto the toilet seat has a paper feeding mechanism and a paper cutting mechanism operated by an electronic control unit. A specified length of paper appropriate for covering the toilet seat is automatically and accurately fed and positioned on the toilet seat. After use, the seat covering paper can automatically be cut off. For lavatories at public sites in particular, since the user can operate the apparatus to paper feed from a functional casing to provide a new seat covering paper on the toilet seat for each use, the user can be assured of a clean toilet seat. Also, since the seat covering paper is held immovably on the toilet seat, the use of the paper-covered toilet is made easier.

公开(公告)号：US4926505A

公开(公告)日：1990-05-22

申请号：US271134

申请日：1988-11-14

申请人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto ,  Osamu Yamamoto ,  Shokichi Fujii ,  Katsumi Nonomura

发明人： Mitsuhiro Higuchi ,  Hirofumi Yamamoto ,  Osamu Yamamoto ,  Shokichi Fujii ,  Katsumi Nonomura

IPC分类号： A47K13/20

CPC分类号： A47K13/20

摘要： A toilet seat structure capable of automatically feeding a seat covering paper onto a toilet seat substantially comprises a seat covering paper roll disposed at the rear end of a toilet seat body, a seat covering paper feeding mechanism which is provided with a press plate, a seat covering paper tearing mechanism, a control unit for controlling the seat covering paper feeding mechanism and the seat covering paper tearing mechanism and tension applying means for applying tension to the seat covering paper, wherein the seat covering paper which is subjected to tension is cut by applying a pressure thereto by means of the press plate. Due to such construction, the tearing edge of the press plate can be formed in a round shape so that wear of the cutting edge which is generated through the tearing operation can be miminized whereby maintenance or repairing can be also minimized.

公开(公告)号：US10150966B2

公开(公告)日：2018-12-11

申请号：US15123623

申请日：2015-03-04

申请人： Hirofumi Yamamoto ,  Masaki Mori

发明人： Hirofumi Yamamoto ,  Masaki Mori ,  Yuichiro Doki

IPC分类号： A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  A61K47/02 ,  A61K9/00 ,  A61K9/51

摘要： Provided is a novel useful microRNA having improved anti-tumor activity, obtained by introducing a variation in a microRNA which is present in-vivo and which exhibits an anti-tumor effect. This microRNA containing a base sequence (SEQ ID NO: 1) obtained by varying a predetermined region of the base sequence of miR-29b is able to exhibit a particularly outstanding anti-tumor effect.

公开(公告)号：US09889155B2

公开(公告)日：2018-02-13

申请号：US15119862

申请日：2015-02-20

申请人： Hirofumi Yamamoto ,  Masaki Mori

发明人： Hirofumi Yamamoto ,  Masaki Mori ,  Yuichiro Doki ,  Xin Wu

IPC分类号： A61K33/06 ,  A61K31/513 ,  A61K33/24 ,  A61K31/555 ,  A61K31/337 ,  A61K31/704

CPC分类号： A61K33/06 ,  A61K31/337 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K33/24 ,  A61K2300/00

摘要： An object of the present invention is to provide an agent that potentiates the antitumor effect of an anticancer agent by allowing efficient accumulation of the anticancer agent in tumor tissue. The administration of carbonate apatite with the anticancer agent allows efficient accumulation of the anticancer agent in the tumor tissue to dramatically potentiate the antitumor effect of the anticancer agent.

公开(公告)号：US20140075458A1

公开(公告)日：2014-03-13

申请号：US13609258

申请日：2012-09-11

申请人： Stephen Wright ,  Hirofumi Yamamoto ,  Pak Kiu Chung ,  Raju Ramanathan ,  Krishnan Menon ,  Lawrence Osterman ,  Alan Stephenson ,  Reed Townsend ,  Jacob Rossi

发明人： Stephen Wright ,  Hirofumi Yamamoto ,  Pak Kiu Chung ,  Raju Ramanathan ,  Krishnan Menon ,  Lawrence Osterman ,  Alan Stephenson ,  Reed Townsend ,  Jacob Rossi

IPC分类号： G06F3/00

CPC分类号： G06F3/038 ,  G06F9/4411 ,  G06F9/451

摘要： In one embodiment, a unified pointer message 300 may describe in a single type of pointer message a coordinate input from a user via multiple types of pointer devices. An input device interface 150 may receive a coordinate input 350 from an input device. A processor 120 may execute an application programming interface layer 430 that creates a unified pointer message 300 for the coordinate input 350. The processor 120 may send the unified pointer message 300 to an application. The processor 120 may process a device specific data set 244 unhandled by the application.

摘要翻译： 在一个实施例中，统一指针消息300可以以单一类型的指针消息描述来自用户经由多种类型的指针设备的坐标输入。 输入设备接口150可以从输入设备接收坐标输入350。 处理器120可以执行应用编程接口层430，其创建用于坐标输入350的统一指针消息300.处理器120可以将统一指针消息300发送到应用。 处理器120可以处理由应用程序未处理的设备特定数据集244。

公开(公告)号：US08398010B2

公开(公告)日：2013-03-19

申请号：US13521380

申请日：2011-01-05

申请人： Shinnosuke Tomita ,  Hirofumi Yamamoto ,  Kiyoshi Akazawa ,  Takayuki Yoshimiya

发明人： Shinnosuke Tomita ,  Hirofumi Yamamoto ,  Kiyoshi Akazawa ,  Takayuki Yoshimiya

IPC分类号： B65H55/04

CPC分类号： B65H55/04 ,  B65H2701/313

摘要： A polyester monofilament package is formed by reeling a polyester monofilament comprising polyethylene terephthalate and satisfies all of the following requirements (a) to (d): (a) the coefficient of dynamic friction between yarns of the polyester monofilament being 0.13 μd or less; (b) the package end being in a tapered shape with a taper angle (0) of 75° or less; (c) the variation gradient in unreeling tension (AT) being 0.02 cN/dtex-m or less; and (d) in a part of a reeling thickness of 1 mm in the inner layer of the package, the variation in contraction stress of the polyester monofilament being 3.0 cN/dtex or less.

摘要翻译： 通过缠绕包含聚对苯二甲酸乙二醇酯的聚酯单丝来形成聚酯单丝包装，并且满足以下所有要求（a）至（d）：（a）聚酯单丝的纱线之间的动摩擦系数为0.13μd以下; （b）封装端部呈锥形（0）为75°以下的锥形， （c）未拉伸张力（AT）的变化梯度为0.02cN / dtex-m以下; 和（d）在包装的内层中的卷取厚度为1mm的一部分中，聚酯单丝的收缩应力的变化为3.0cN / dtex以下。

公开(公告)号：US08357688B2

公开(公告)日：2013-01-22

申请号：US13254368

申请日：2010-03-04

申请人： Hiroyuki Kaizawa ,  Mari Sugita ,  Hidenori Azami ,  Ryushi Seo ,  Takaho Nomura ,  Satoshi Yamamoto ,  Hirofumi Yamamoto ,  Kazuyuki Tsuchiya ,  Hideki Kubota ,  Kazunori Kamijo

发明人： Hiroyuki Kaizawa ,  Mari Sugita ,  Hidenori Azami ,  Ryushi Seo ,  Takaho Nomura ,  Satoshi Yamamoto ,  Hirofumi Yamamoto ,  Kazuyuki Tsuchiya ,  Hideki Kubota ,  Kazunori Kamijo

IPC分类号： A61K31/495

CPC分类号： C07D498/04 ,  C07D487/04 ,  C07D491/107 ,  C07D519/00

摘要： Substituted imidazo[1,5-a]quinoxalin-4(5H)-ones are useful as PDE9 inhibitors.

摘要翻译： 取代的咪唑并[1,5-a]喹喔啉-4（5H） - 酮可用作PDE9抑制剂。

公开(公告)号：US20120159363A1

公开(公告)日：2012-06-21

申请号：US12970904

申请日：2010-12-16

申请人： Gabriel DeBacker ,  Alex Snitkovskiv ,  Chris Guzak ,  John Stephens ,  Thomas Olsen ,  Mohamed Sadek ,  Hirofumi Yamamoto ,  Robert Jarrett ,  David Abzarian ,  Alice Tang ,  Jennifer Nan ,  Adrian Ford ,  Chaitanya Sareen

发明人： Gabriel DeBacker ,  Alex Snitkovskiv ,  Chris Guzak ,  John Stephens ,  Thomas Olsen ,  Mohamed Sadek ,  Hirofumi Yamamoto ,  Robert Jarrett ,  David Abzarian ,  Alice Tang ,  Jennifer Nan ,  Adrian Ford ,  Chaitanya Sareen

IPC分类号： G06F3/048

CPC分类号： G06F9/451

摘要： The subject disclosure relates to managing z-dimensional ordering of elements within a computing system display through the use of z-order bands. As described herein, z-order bands are utilized to arrange windows and other graphics corresponding to respective application types. A policy engine controls which windows and/or other graphical elements can enter and exit each band. Graphical elements within a given band can additionally be subject to per-band properties corresponding to the band and/or user preferences. As additionally described herein, z-order bands and/or other suitable mechanisms are utilized to facilitate registration watermarking for a computing environment by rendering a registration watermark display upon determining that one or more licensed elements of a computing system have not been registered. The registration watermark display is assigned a z-order band that enables its display over all other graphical elements associated with the computing system and prevents other graphical elements from interfering with its display.

摘要翻译： 本公开涉及通过使用z阶频带来管理计算系统显示器内的元件的z维排序。 如本文所述，z阶频带用于布置对应于各个应用类型的窗口和其他图形。 策略引擎控制哪些窗口和/或其他图形元素可以进入和退出每个频带。 给定频带内的图形元素可另外经受对应于频带和/或用户偏好的每频段特性。 如本文另外描述的，使用z阶频带和/或其他合适的机制来通过在确定计算系统的一个或多个许可元件尚未被注册之后呈现注册水印显示来促进计算环境的注册水印。 注册水印显示被分配一个z阶带，使其能够显示在与计算系统相关联的所有其它图形元素上，并防止其他图形元素干扰其显示。

公开(公告)号：US20070028294A1

公开(公告)日：2007-02-01

申请号：US11193312

申请日：2005-07-30

申请人： Hirofumi Yamamoto ,  Mohamed Fathalla ,  Yashabh Sethi ,  Richard Ward

发明人： Hirofumi Yamamoto ,  Mohamed Fathalla ,  Yashabh Sethi ,  Richard Ward

IPC分类号： H04L9/32

CPC分类号： H04L63/101 ,  G06F21/6218 ,  G06F2221/2105 ,  G06F2221/2141 ,  H04L63/1441

摘要： In aspects, interactions between processes of a desktop are allowed or denied based on security data. The security data may comprise a first bitmap that indicates whether a requesting process is allowed to cause an action to occur, a second bitmap that indicates whether a process is protected from having an action occur, and a third bitmap that indicates whether the requesting process may override protection, if any, in causing the action to occur.

摘要翻译： 在一些方面，基于安全性数据允许或拒绝桌面进程之间的交互。 安全数据可以包括指示请求进程是否允许发生动作的第一位图，指示进程是否被保护以防止发生动作的第二位图，以及指示请求进程是否可以 超越保护（如果有的话）导致动作发生。