摘要:
A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.
摘要:
A novel cephalosporin derivative of the formula: ##STR1## [wherein X is hydrogen, hydroxyl, acyloxy, alkoxy, carbamoyloxy, quaternary ammonium or a group of the formula --SR.sup.1 (where R.sup.1 is a nitrogen-containing heterocyclic group)] or a pharmaceutically acceptable salt or ester thereof is found to have potent antibiotic activity against various bacteria, particularly against gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri and Citrobacter freundii.
摘要:
2-Oxoazetidine derivatives represented by the formula; ##STR1## wherein R.sup.1 stands for phthalimido group, benzyloxycarbonylamino group, a halogen on an alkyl group which may have hydroxyl group, R.sup.2 stands for hydrogen, an alkyl group, an alkylthio group or an arylthio group, and R.sup.3 and R.sup.4 independently stand for an acyl group or cyano group, and a method of preparing them, which is shown by the following reaction scheme; ##STR2## wherein R.sup.5 stands for a carboxyl-protective group, and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are of the same meanings as defined above.This compound (I) can be utilized as intermediates for carba-2-penem compounds having excellent anti-bacterial activity and .beta.-lactamase inhibitory activity.
摘要:
Novel [2-(syn)-carbamoyloximinoacetamido]cephalosporins of the formula: ##STR1## [wherein, Y.sup.1 is hydrogen, hydroxyl, carbamoyloxy, acyloxy, quaternary ammonium or nitrogen-containing heterocyclic thio; R.sup.1 is alkyl, aralkyl or aryl; R.sup.2 is hydrogen or an ester residue; k is 0 or 1] and a salt thereof show strong antibacterial activities particularly against Gram-negative bacteria and they are useful as antibacterial agents.
摘要:
A compound of the formula: ##STR1## wherein R.sub.1 is a hydrogen atom or a lower alkyl group; R.sub.2 is an unsubstituted or lower alkyl-substituted alicyclic alkyl group of 3 to 12 carbon atoms or a C.sub.3-6 alicyclic alkyl-substituted lower alkyl group or a pharmaceutically acceptable salt thereof, processes for preparing the same, a pharmaceutical composition thereof are provided. The compound has an improved absorbability and can be orally applied as antibiotics.
摘要:
A compound of the formula: ##STR1## or a pharmaceutical acceptable salt thereof, processes for preparing the same and a pharmaceutical composition containing the compound or the salt thereof mentioned above are provided. The compound has antibiotic activity and has improved absorbability.
摘要:
An image processing device provides a detection result of additional information added to each of pages which constitute a document. The image processing device includes an input part which inputs image data of each page of a document. A detection part generates a page detection result of additional information added to the image data, the page detection result being generated on a page basis and indicating a result of detection of the additional information for each page. A detection result output part outputs an outline result indicating an outline of the page detection results for the respective pages on a document basis, together with an identifier of the document associated with the outline result.
摘要:
A display control device includes an acquiring unit that acquires a display request of display information including a display item with respect to a device; a first storage unit that stores therein a minimum item size that is a minimum value of an item size of the display item displayed on a display screen on which the display information is to be displayed; an item size determination unit that sets, based on a screen size of the display screen, an item size of the display item when displayed on the display screen, to an item size that is equal to or larger than the minimum item size; and a display information generating unit that generates the display information including the display item having the set item size.
摘要:
A method and an apparatus capable of measuring the density of steam within a steam pipe even in limited environmental conditions such as in a steam injection well. A vessel which accommodates therein first and second neutron detectors disposed in mutual longitudinal alignment with a neutron source interposed therebetween and in which the second detector is covered with a neutron shield capable of absorbing thermal neutrons while allowing epithermal neutrons to penetrate therethrough is inserted into the steam pipe together with a thermal neutron shielding sheet completely encircling the vessel. From the neutrons which were emitted from the neutron source and passed out and back through the neutron shield and the steam region, those epithermal neutrons which have not undergone transformation to thermal neutrons within the steam region are detected by both the first and second detectors, while the thermal neutrons resulting from the transformation are detected by the first detector only. The steam density is determined on the basis of a cadmium ratio derived from the counts of the two detectors.
摘要:
A press machine is disclosed which is provided with a plurality of press dies fixedly secured on a bolster. The machine has a vertically reciprocable frame member with a predetermined constant stroke, which carries a plurality of pressure plates cooperating with the die, respectively. Each pressure plate is axially movable with respect to the frame member and threadedly connected with a spacer plate arranged between the frame member and the pressure plate. The shut height of the machine can be individually adjusted for each pressure plate, by rotating the spacer plate relative to the pressure plate. The shut height can be optimized very easily and in short a time so that the productivity can considerably be improved.