公开(公告)号：US11351242B1

公开(公告)日：2022-06-07

申请号：US16788182

申请日：2020-02-11

Applicant: ModernaTX, Inc.

Inventor： Lori Panther ,  Christine Shaw ,  Igor Smolenov ,  Michael Watson ,  Tal Zaks

IPC: A61K39/12 ,  A61K9/51 ,  A61K39/00

Abstract: Provided herein are vaccine composition comprising a chemically-modified messenger ribonucleic acid (mRNA) encoding a hMPV fusion (F) glycoprotein and a chemically-modified mRNA encoding a hPIV3 F glycoprotein formulated in a cationic lipid nanoparticle formulation, and related method for inducing an antigen-specific immune response.

公开(公告)号：US20220378904A1

公开(公告)日：2022-12-01

申请号：US17737581

申请日：2022-05-05

Applicant: ModernaTX, Inc.

Inventor： Lori Panther ,  Christine Shaw ,  Igor Smolenov ,  Michael Watson ,  Tal Zaks

IPC: A61K39/12 ,  A61K9/51

Abstract: Provided herein are vaccine composition comprising a chemically-modified messenger ribonucleic acid (mRNA) encoding a hMPV fusion (F) glycoprotein and a chemically-modified mRNA encoding a hPIV3 F glycoprotein formulated in a cationic lipid nanoparticle formulation, and related method for inducing an antigen-specific immune response.