公开(公告)号：US11007260B2

公开(公告)日：2021-05-18

申请号：US15746286

申请日：2016-07-21

Applicant: ModernaTX, Inc.

Inventor： Giuseppe Ciaramella ,  Eric Yi-Chun Huang ,  Kapil Bahl ,  Tai Zaks ,  Sunny Himansu

IPC: A61K39/12 ,  A61K9/00 ,  C07K16/28 ,  C07K14/005 ,  C07K16/10 ,  C07K14/18 ,  A61K48/00 ,  A61K9/14 ,  A61K47/10 ,  A61K47/18 ,  A61K47/22 ,  A61K47/28 ,  C12N7/00 ,  A61P31/12 ,  A61P31/14 ,  A61K9/51 ,  A61K39/00

Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.