公开(公告)号：US10047126B2

公开(公告)日：2018-08-14

申请号：US15301310

申请日：2015-04-01

Applicant: Monash University

Inventor： Jian Li ,  Roger Nation ,  Tony Velkov ,  Philip Thompson ,  Kade D. Roberts

IPC: C07K7/62 ,  A61K38/12 ,  A61K38/00

Abstract: The present invention relates to antimicrobial compounds and their uses, and in particular to peptide antibiotics which may be used in the treatment of bacterial infections such as Gram-negative bacterial infections, particularly those caused by multidrug-resistant (MDR) pathogens.

公开(公告)号：US11225505B2

公开(公告)日：2022-01-18

申请号：US15763954

申请日：2016-09-29

Applicant: MONASH UNIVERSITY

Inventor： Kade D. Roberts ,  Jian Li ,  Tony Velkov ,  Roger L. Nation ,  Philip E. Thompson

IPC: C07K7/62 ,  A61P31/04 ,  A61K38/12 ,  A61K45/06 ,  A61K38/00

Abstract: The present invention relates to antimicrobial polymyxin derivative compounds and their uses, and in particular to peptide polymyxin antibiotics which may be used in the treatment of bacterial infections such as Gram negative bacterial infections, particularly those caused by multidrug-resistant (MDR) Gram negative bacterial infections.

公开(公告)号：USRE48335E1

公开(公告)日：2020-12-01

申请号：US16144967

申请日：2018-09-27

Applicant: Monash University

Inventor： Jian Li ,  Roger Nation ,  Tony Velkov ,  Philip Thompson ,  Kade D. Roberts

IPC: C07K7/62 ,  A61K38/12 ,  A61K38/00

Abstract: The present invention relates to antimicrobial compounds and their uses, and in particular to peptide antibiotics which may be used in the treatment of bacterial infections such as Gram-negative bacterial infections, particularly those caused by multidrug-resistant (MDR) pathogens.

公开(公告)号：US20180282374A1

公开(公告)日：2018-10-04

申请号：US15763954

申请日：2016-09-29

Applicant: MONASH UNIVERSITY

Inventor： Kade D. Roberts ,  Jian Li ,  Tony Velkov ,  Roger L. Nation ,  Philip E. Thompson

IPC: C07K7/62 ,  A61K38/12 ,  A61K45/06 ,  A61P31/04

Abstract: The present invention relates to antimicrobial polymyxin derivative compounds and their uses, and in particular to peptide polymyxin antibiotics which may be used in the treatment of bacterial infections such as Gram negative bacterial infections, particularly those caused by multidrug-resistant (MDR) Gram negative bacterial infections.