公开(公告)号：US20240344028A1

公开(公告)日：2024-10-17

申请号：US18580280

申请日：2022-07-22

申请人： Mosa Meat B.V.

发明人： Rada MITIC ,  Federica CANTONI ,  Sophie Claire HUBALEK ,  Laura JACKISCH ,  Arianna MEI ,  Johanna MELKE

IPC分类号： C12N5/077 ,  A23D9/00 ,  A23L13/00 ,  C12N5/00

CPC分类号： C12N5/0653 ,  A23D9/00 ,  A23L13/00 ,  C12N5/0037 ,  C12N2500/36 ,  C12N2500/38 ,  C12N2500/46 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/155 ,  C12N2501/33 ,  C12N2501/385 ,  C12N2501/39

摘要： The invention provides inter alia a method for differentiating an adipogenic progenitor cell. comprising the step of:—culturing an adipogenic progenitor cell in a serum-free medium for differentiating an adipogenic progenitor cell. wherein the serum-free medium comprises:—at least one peroxisome proliferator-activated receptor gamma (PPARy) agonist:—at least one hormone selected from the group consisting of insulin and hydrocortisone:—at least one cytokine and/or growth factor selected from the group consisting of bone morphogenetic protein 4 (BMP4) and epidermal growth factor (EGF); and-ascorbic acid or a derivative thereof.