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Patent Agency Ranking
公开(公告)号：US20170173309A1
公开(公告)日：2017-06-22
申请号：US15453194
申请日：2017-03-08
Applicant: Muffin Incorporated
Inventor： Frank J. Fischer, JR. , James R. Randolph , Neal E. Fearnot , Jimmy L. Taylor, JR. , Gary B. Shirley
Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.
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公开(公告)号：US20200147354A1
公开(公告)日：2020-05-14
申请号：US16742061
申请日：2020-01-14
Applicant: Muffin Incorporated
Inventor： Frank J. Fischer, JR. , James R. Randolph , Neal E. Fearnot , Jimmy L. Taylor, JR. , Gary B. Shirley
Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.
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公开(公告)号：US20140257090A1
公开(公告)日：2014-09-11
申请号：US14196200
申请日：2014-03-04
Applicant: Muffin Incorporated
Inventor： Frank J. Fischer, JR. , Kem Hawkins , Neal E. Fearnot
CPC classification number: A61B8/42 , A61B8/0891 , A61B8/445 , A61M25/0026 , A61M2025/09133
Abstract: A medical device includes a guidewire with a lumen, a plastic tip, and a removable mandrel. The medical device has echogenic properties which can be altered between an echogenic state and an echolucent state by evacuating the lumen and applying a liquid or gas within the lumen.
Abstract translation: 医疗装置包括具有内腔的导丝，塑料尖端和可移除心轴。 医疗装置具有回声特性，其可以在回声状态和回波状态之间通过抽空腔并在腔内施加液体或气体来改变。
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公开(公告)号：US20130338637A1
公开(公告)日：2013-12-19
申请号：US13910693
申请日：2013-06-05
Applicant: Muffin Incorporated , Cook Medical Technologies LLC
Inventor： Frank J. Fischer, JR. , James R. Randolph , Neal E. Fearnot , Jimmy L. Taylor, JR. , Gary Bradford Shirley
IPC: A61M25/10
CPC classification number: A61M25/1011 , A61B34/20 , A61M25/0026 , A61M25/0041 , A61M25/0068 , A61M25/007 , A61M25/10 , A61M37/0092 , A61M2025/0003 , A61M2025/0004 , A61M2025/0042 , A61M2025/1015 , A61M2025/1052 , A61M2025/1061 , A61M2025/1093
Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.
Abstract translation: 一方面描述了一种用于细胞或其它疗法的多压力监测系统，包括具有用于接受治疗装置的第一腔的第一导管，用于充气气囊的第二腔，用于监测第一腔内的流体压力的压力传感器， 以及限流器，例如止血阀，用于在第一腔内存在或更换治疗装置的同时限制流体进入和离开第一腔的流体。 还公开了一种使用具有耦合到第一压力传感器的第一压力监测器的第一导管以及连接到耦合到第二压力监测器的第二压力传感器的第二导管的方法。 在治疗操作期间，第二导管定位在第一导管的第一腔内，并且在整个过程中使用第一和第二压力监测器来验证适当的压力。 还描述了用于向患者递送可流动治疗物质（例如活细胞制剂）的新颖方法，系统和导管。
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公开(公告)号：US20140276368A1
公开(公告)日：2014-09-18
申请号：US14211702
申请日：2014-03-14
Applicant: Muffin Incorporated
Inventor： Richard B. Sisken , Ryan Pruchnic , Frank J. Fischer, JR. , Steven Charlebois
IPC: A61M5/158
CPC classification number: A61M5/34 , A61B18/24 , A61M5/1582 , A61M25/0069 , A61M25/007
Abstract: Methods and apparatus are provided for treating tissue with apparatus that includes an priming portion for initiating a healing response in the tissue to be treated, and which delivers a bioactive agent during or after preparing tissue adjacent the apparatus, as by generating or aiding a healing, regeneration or repair response in the tissue. The priming portion may comprise an abrasive surface, fluid ejection ports, and/or stimulation by electrical, thermal, or light energy.
Abstract translation: 提供了用于处理组织的方法和装置，所述设备包括用于在待治疗组织中起始愈合反应的引发部分，并且在制备邻近所述装置的组织中或之后递送生物活性剂，如通过产生或辅助愈合， 组织中的再生或修复反应。 起动部分可以包括研磨表面，流体喷射口，和/或通过电，热或光能的刺激。
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