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公开(公告)号：US12029648B2
公开(公告)日：2024-07-09
申请号：US17097623
申请日：2020-11-13
Applicant: Muffin Incorporated
Inventor： William J. Havel , Jeremy T. Newkirk , Rita Hadley , Yun Zhou
CPC classification number: A61F2/2466 , A61B17/04 , A61B2017/0409 , A61B17/0485 , A61B2017/0488 , A61B2017/0496 , A61F2220/0075
Abstract: Among other things, there are disclosed embodiments of devices used for minimally-invasive treatments, such as treatment of mitral valves. In a system for placing an annuloplasty belt around the heart, embodiments for tensioning a suture associated with the belt are provided, as are embodiments of a suture lock for holding the suture with the applied tension. A delivery device that permits placement and tensioning of such a belt and activation of the suture lock in one procedure is also disclosed. Methods for making and using these features are also disclosed.
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公开(公告)号：US20230285018A1
公开(公告)日：2023-09-14
申请号：US18319065
申请日：2023-05-17
Applicant: Muffin Incorporated
Inventor： Gregory James Hardy , Shaun Davis Gittard , John C. Sigmon, JR. , William J. Havel , Jeremy T. Newkirk , Neal E. Fearnot , Rita Hadley
CPC classification number: A61B17/08 , A61B17/10 , A61B17/0057 , A61B2017/081 , A61B2017/00619 , A61B2017/00597 , A61B2017/00606 , A61B2017/00592 , A61B17/12122
Abstract: There are shown and described embodiments of a closure device for closing holes in tissue, for example in the right atrial appendage. The closure device in particular embodiments includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for the closure device are also described.
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公开(公告)号：US20220280696A1
公开(公告)日：2022-09-08
申请号：US17527679
申请日：2021-11-16
Applicant: Muffin Incorporated , Cook Biotech Incorporated
Inventor： Michael C. Hiles , Chad E. Johnson , Neal E. Fearnot , Thomas Payne , Ronald Jankowski
Abstract: Described are methods, cell growth substrates, and devices that are useful in preparing cell-containing graft materials for administration to patients. Tubular passages can be defined in cell growth substrates to promote distribution of cells into the substrates. Also described are methods and devices for preparing cell-seeded graft compositions, methods and devices for preconditioning cell growth substrates prior to application of cells, and cell seeded grafts having novel substrates, and uses thereof.
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公开(公告)号：US11376110B2
公开(公告)日：2022-07-05
申请号：US16503675
申请日：2019-07-05
Applicant: Muffin Incorporated , Cook Medical Technologies LLC
Inventor： Neal Fearnot , Sarah Robbins , Marc C. Buhrmester , Joshua Krieger
Abstract: Storage devices, loading devices, delivery systems, kits, and associated methods for implantable medical devices are described. An example embodiment of a storage device includes a storage member, a first cap, and a second cap. The storage member has a first end, a second end, and a main body that defines a first opening, a second opening, a passageway, a separating wall, and a plurality of holes. The passageway has a first portion and a second portion. The first portion extends from the first end of the storage member to the separating wall and the second portion extends from the second end of the storage member to the separating wall. Each hole of the plurality of holes extends through the separating wall and provides access between the first portion and the second portion. Each of the first and second caps is releasably attached to the storage member.
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公开(公告)号：US20220177824A1
公开(公告)日：2022-06-09
申请号：US17310261
申请日：2020-01-28
Inventor： Neal Fearnot , Sarah Robbins , Marc Buhrmester , Joshua Krieger , Gabriel Converse
Abstract: Material processing apparatus, systems, methods, and products are described. An example of a material processing apparatus includes a holding member, a base, a tensioning member, an actuator, and a first inner member. The holding member defines a holding member passageway. The base is attached to the holding member. The tensioning member is partially disposed within the holding member passageway. The tensioning member defines a tensioning member passageway. The tensioning member is moveable relative to the holding member between a first position and a second position. The actuator is attached to the tensioning member and is moveable in a first direction and a second direction. Movement of the actuator results in movement of the tensioning member between its first position and second position. The first inner member is adapted to be disposed within the tensioning member passageway.
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Patent Agency Ranking
公开(公告)号：US20220008060A1
公开(公告)日：2022-01-13
申请号：US17385230
申请日：2021-07-26
Applicant: Muffin Incorporated , National Institutes of Health, an Agency of the Department of Health and Human Services
Inventor： Shaun Davis Gittard , Gregory James Hardy , John C. Sigmon, JR. , Jeremy T. Newkirk , William J. Havel , Neal E. Fearnot , Toby Rogers , Kanishka Ratnayaka , Robert L. Lederman
Abstract: Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown.
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公开(公告)号：US20210259836A1
公开(公告)日：2021-08-26
申请号：US17261053
申请日：2019-07-05
Inventor： Neal Fearnot , Sarah Robbins , Marc C. Buhrmester , Joshua Krieger
Abstract: Storage devices, loading devices, delivery systems, kits, and associated methods for implantable medical devices are described. An example embodiment of a storage device includes a storage member, a first cap, and a second cap. The storage member has a first end, a second end, and a main body that defines a first opening, a second opening, a passageway, a separating wall, and a plurality of holes. The passageway has a first portion and a second portion. The first portion extends from the first end of the storage member to the separating wall and the second portion extends from the second end of the storage member to the separating wall. Each hole of the plurality of holes extends through the separating wall and provides access between the first portion and the second portion. Each of the first and second caps is releasably attached to the storage member.
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公开(公告)号：US20210059818A1
公开(公告)日：2021-03-04
申请号：US17097623
申请日：2020-11-13
Applicant: Muffin Incorporated
Inventor： William J. Havel , Jeremy T. Newkirk , Rita Hadley , Yun Zhou
Abstract: Among other things, there are disclosed embodiments of devices used for minimally-invasive treatments, such as treatment of mitral valves. In a system for placing an annuloplasty belt around the heart, embodiments for tensioning a suture associated with the belt are provided, as are embodiments of a suture lock for holding the suture with the applied tension. A delivery device that permits placement and tensioning of such a belt and activation of the suture lock in one procedure is also disclosed. Methods for making and using these features are also disclosed.
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公开(公告)号：US10568628B2
公开(公告)日：2020-02-25
申请号：US15602457
申请日：2017-05-23
Applicant: Muffin Incorporated
Inventor： Gregory James Hardy , Shaun Davis Gittard , John C. Sigmon, Jr. , William J. Havel , Jeremy T. Newkirk , Neal E. Fearnot , Rita Hadley
Abstract: There are shown and described embodiments of a closure device for closing holes in tissue, for example in the right atrial appendage. The closure device in particular embodiments includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for the closure device are also described.
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公开(公告)号：US10532193B2
公开(公告)日：2020-01-14
申请号：US15453194
申请日：2017-03-08
Applicant: Muffin Incorporated
Inventor： Frank J. Fischer, Jr. , James R. Randolph , Neal E. Fearnot , Jimmy L. Taylor, Jr. , Gary B. Shirley
Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.
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