Methods and apparatus for automated base-calling on multiple DNA strands
    8.
    发明授权
    Methods and apparatus for automated base-calling on multiple DNA strands 有权
    在多个DNA链上进行自动基本呼叫的方法和装置

    公开(公告)号:US08126235B2

    公开(公告)日:2012-02-28

    申请号:US12418933

    申请日:2009-04-06

    IPC分类号: G06K9/00

    摘要: In some aspects, a method of automated base-calling using at least one image obtained from a chemical sequencing process performed simultaneously on a plurality of DNA strands, the at least one image including intensity information corresponding to locations of at least one base in the plurality of DNA strands is provided. The method comprises processing the at least image to obtain a function corresponding to the intensity information in the at least one image for the at least one base, the function incorporating intensity information corresponding to each of the plurality of DNA strands, identifying a plurality of peaks in the function, the plurality of peaks indicating possible locations for the at least one base in the plurality of DNA strands, assigning membership to each of the plurality of peaks by determining whether each of the plurality of peaks is believed to have resulted from none, one or multiple of the plurality of DNA strands, and computing a sequence for the at least one base for each of the plurality of DNA strands based, at least in part, on the membership assignment.

    摘要翻译: 在一些方面,一种使用从多个DNA链同时执行的化学测序过程获得的至少一个图像进行自动基本呼叫的方法,所述至少一个图像包括对应于多个基因中至少一个基因位置的强度信息 的DNA链。 所述方法包括处理所述至少一个图像以获得对应于所述至少一个基底的所述至少一个图像中的强度信息的函数,所述功能包括对应于所述多个DNA链中的每一个的强度信息,识别多个峰 在所述功能中,所述多个峰指示所述多个DNA链中所述至少一个碱基的可能位置,通过确定所述多个峰中的每一个是否被认为是由所述多个峰中的每一个赋予的, 至少部分地基于成员分配来计算多个DNA链中的一个或多个,以及针对所述多个DNA链中的每一个为所述至少一个碱基计算序列。

    METHODS AND APPARATUS FOR AUTOMATED BASE-CALLING ON MULTIPLE DNA STRANDS
    9.
    发明申请
    METHODS AND APPARATUS FOR AUTOMATED BASE-CALLING ON MULTIPLE DNA STRANDS 有权
    用于自动基因多态DNA检测的方法和装置

    公开(公告)号:US20100074492A1

    公开(公告)日:2010-03-25

    申请号:US12418933

    申请日:2009-04-06

    IPC分类号: G06K9/00

    摘要: In some aspects, a method of automated base-calling using at least one image obtained from a chemical sequencing process performed simultaneously on a plurality of DNA strands, the at least one image including intensity information corresponding to locations of at least one base in the plurality of DNA strands is provided. The method comprises processing the at least image to obtain a function corresponding to the intensity information in the at least one image for the at least one base, the function incorporating intensity information corresponding to each of the plurality of DNA strands, identifying a plurality of peaks in the function, the plurality of peaks indicating possible locations for the at least one base in the plurality of DNA strands, assigning membership to each of the plurality of peaks by determining whether each of the plurality of peaks is believed to have resulted from none, one or multiple of the plurality of DNA strands, and computing a sequence for the at least one base for each of the plurality of DNA strands based, at least in part, on the membership assignment.

    摘要翻译: 在一些方面,一种使用从多个DNA链同时执行的化学测序过程获得的至少一个图像进行自动基本呼叫的方法,所述至少一个图像包括对应于多个基因中至少一个基因位置的强度信息 的DNA链。 所述方法包括处理所述至少一个图像以获得对应于所述至少一个基底的所述至少一个图像中的强度信息的函数,所述功能包括对应于所述多个DNA链中的每一个的强度信息,识别多个峰 在所述功能中,所述多个峰指示所述多个DNA链中所述至少一个碱基的可能位置,通过确定所述多个峰中的每一个是否被认为是由所述多个峰中的每一个赋予的, 至少部分地基于成员分配来计算多个DNA链中的一个或多个,以及针对所述多个DNA链中的每一个为所述至少一个碱基计算序列。

    RATE MATCHING AND SCRAMBLING TECHNIQUES FOR CONTROL SIGNALING
    10.
    发明申请
    RATE MATCHING AND SCRAMBLING TECHNIQUES FOR CONTROL SIGNALING 有权
    用于控制信号的速率匹配和扫描技术

    公开(公告)号:US20090046808A1

    公开(公告)日:2009-02-19

    申请号:US12170416

    申请日:2008-07-09

    IPC分类号: H04L27/12

    摘要: Embodiments of the present disclosure provide a transmitter, a receiver and methods of operating a transmitter and a receiver. In one embodiment, the transmitter includes an input padding module configured to provide padded bits having padding bits added to payload bits for one or more control channels, and a scrambling module configured to apply a masking sequence to one or more of the padded bits to generate scrambled bits. Additionally, the transmitter also includes an encoding module configured to perform forward error correction encoding and rate matching on the scrambled bits to obtain a required number of control channel output bits, and a transmit module configured to transmit the control channel output bits for one or more control channels.

    摘要翻译: 本公开的实施例提供发射机,接收机和操作发射机和接收机的方法。 在一个实施例中,发射机包括:输入填充模块,其被配置为提供填充比特,其具有添加到一个或多个控制信道的有效载荷比特的填充比特;以及加扰模块,被配置为向一个或多个填充比特应用屏蔽序列以产生 乱码 此外,发射机还包括编码模块,其被配置为对加扰比特执行前向纠错编码和速率匹配,以获得所需数量的控制信道输出比特;以及发射模块,被配置为发送用于一个或多个的控制信道输出比特 控制通道。