摘要:
A phosphodiesterase IV inhibiting cathecol derivatives of the general formula I: ##STR1## or a pharmaceutically acceptable salt thereof in which R1 is C.sub.1-7 alkyl; C.sub.3-7 cycloalkane; phenyl optionally substituted with lower alkyl lower alkoxy, nitro or halogen; pyrimidine optionally substituted with lower alkyl, lower alkoxy, nitro or halogen; or pyridine optionally substituted with lower alkyl, lower alkoxy, nitro or halogen; X, Y and Z are each independently oxygen, nitrogen or sulfur optionally substituted with C.sub.1-7 alkyl, C.sub.3-7 cycloalkane or phenyl; W is oxygen or sulfur is disclosed. In addition, a process for producing the compound of the general formula I and a pharmaceutical composition containing pharmaceutically effective amount of the compound of the general formula I are disclosed.
摘要:
Novel 4,5-diamino pyrimidine derivatives are described by the following general formula I: in which X is a direct bond, C1-4 alkylene, C1-4 alkyleneoxy, C1-4 alkoxyphenyl or phenyl C1-4 alkylene; Y is a direct bond or C1-2 alkyl, R1 is (i) 5-15 membered cyclic or fused heterocompound which includes one or two atoms selected from a group consisting of nitrogen, oxygen and sulfur and which is substituted with one or two substituents selected from a group consisting of hydrogen, halogen, nitro, hydroxy, C1-6 alkyl, C3-6 alkenyl and halogen C1-4 alkoxy, (ii) C4-10 carbocyclic compound or (iii) hydroxy C1-4 alkoxy, R2 is 5-15 membered cyclic or fused heterocompound which includes one or two nitrogen atoms and, optionally, one oxygen or sulfur atom, and which is substituted with one or two substituents selected from a group consisting of hydrogen, hydroxy, halogen, nitro, hydroxy C1-5 alkyl, C1-6 alkyl, C3-6 alkenyl and halogen C1-4 alkoxy; R3 is hydrogen, in which R4 and R5 are each independently selected from a group consisting of hydroxy, C1-6 alkyl, C3-7 cycloalkyl, C3-6 alkenyl, halogen C1-6 alkyl, halogen C2-6 alkenyl and C1-4alkoxy or R4 and R5 represent each independently in which R6 is selected from a group consisting of hydrogen, hydroxy, C1-6 alkyl, C3-6 alkenyl, halogen C1-6 alkyl, halogen, nitro and C1-4 alkoxy.
摘要:
There is provided a lens module, including: a first lens having positive refractive power, an object-sided surface thereof being convex; a second lens having negative refractive power, an image-sided surface thereof being concave; a third lens having positive refractive power; a fourth lens having negative refractive power, an image-sided surface thereof being convex; and a fifth lens having negative refractive power, an image-sided surface thereof being concave, wherein the fourth lens satisfies Conditional Expression 1, f 4 f
摘要:
The present invention is directed to an aluminum alloy including aluminum as a basic component, silicon, copper, magnesium, iron, manganese, zinc, nickel and the like in a predetermined composition ratio, and a method of manufacturing of a vehicle cylinder liner having excellent wear resistance and heat resistance using the aluminum alloy.The method of manufacturing a vehicle cylinder liner includes the steps of: adding 50˜500 ppm of phosphorus (P) to the aluminum alloy while maintaining a temperature of the aluminum alloy at 700˜800° C. in a holding furnace, stabilizing the molten aluminum alloy including the phosphorus (P) for 30˜60 minutes to reform the molten aluminum alloy, and then continuous-casting the reformed molten aluminum alloy to form a round bar; hot-forging the round bar to forming a cylindrical liner; and machining an internal surface of the cylinder liner, with which a reciprocating piston comes into contact, to allow silicon particles to protrude.
摘要:
There is provided a subminiature imaging optical system utilizing only three sheets of lenses having positive, negative and positive refractive powers, respectively. The subminiature imaging optical system comprising, sequentially from an object side: a first lens having a meniscus shape with a convex object-side surface, the first lens having at least one apherical surface and positive refractive power; a second lens having a meniscus shape with a convex image-side surface, the second lens having at least one spherical surface and negative refractive power; and a third lens having both surfaces formed of an aspherical surface and having positive refractive power.
摘要:
A subminiature imaging optical system including: first, second, third and fourth lenses sequentially positioned from an object side to an image side, the first lens having positive refractivity, the second lens having a concave image-side surface and having negative refractivity, the third lens having negative refractivity, and the fourth lens having positive refractivity, wherein the second lens satisfies following condition 1, and the third lens satisfies following condition 2, 20
摘要:
A subminiature imaging optical system including: first, second, third and fourth lenses sequentially positioned from an object side to an image side, the first lens having positive refractivity, the second lens having a concave image-side surface and having negative refractivity, the third lens having negative refractivity, and the fourth lens having positive refractivity, wherein the second lens satisfies following condition 1, and the third lens satisfies following condition 2, 20
摘要:
There is provided a subminiature imaging optical system utilizing only three sheets of lenses having positive, negative and positive refractive powers, respectively. The subminiature imaging optical system comprising, sequentially from an object side: a first lens having a meniscus shape with a convex object-side surface, the first lens having at least one aspherical surface and positive refractive power; a second lens having a meniscus shape with a convex image-side surface, the second lens having at least one spherical surface and negative refractive power; and a third lens having both surfaces formed of an aspherical surface and having positive refractive power.
摘要:
The present invention relates to a variable focus lens. The variable focus lens comprises a fluid chamber having a protrusion formed along one opened end thereof. The fluid chamber is cylindrically shaped to house first and second non-miscible fluids therein, and the first and second fluids have different refractive indices. A transparent element hermetically is coupled with the opened end of the chamber with a predetermined gap from the protrusion of the chamber. A first electrode is disposed inside the chamber to act on the first fluid, and a second electrode is insulated from the first electrode. The variable focus lens can be easily fabricated to prevent bubble formation with the protrusion formed at the opened end of the chamber.
摘要:
The invention provides a variable focus liquid lens using electrowetting, comprising a conductive first liquid and an insulating second liquid. At least one of the first liquid composed of electrolyte and the second liquid composed of insulating liquid contains a surfactant for reducing interfacial energy between the first and second liquids. An interfacial portion between the first and second liquids is gathered by surfactant to reduce driving voltage. The variable focus liquid lens according to the invention has about 50% lower driving voltage required for changing focus, ensuring stability of the two fluids.