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公开(公告)号：US08718773B2
公开(公告)日：2014-05-06
申请号：US11752775
申请日：2007-05-23
申请人： N. Parker Willis , Axel F. Brisken , Mark W. Cowan , Michael Pare , Robert Fowler , James Brennan
发明人： N. Parker Willis , Axel F. Brisken , Mark W. Cowan , Michael Pare , Robert Fowler , James Brennan
CPC分类号： A61N1/3787 , A61N1/37217 , A61N1/37235 , A61N1/3756
摘要： Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
摘要翻译： 公开了用于优化可植入装置中的声能传输的方法和系统。 传感器元件将声学定位器信号传送到接收器组件，并且接收器用位置信号进行响应。 位置信号可以显示与接收机的位置有关的信息和由接收机接收的所发送的声波的效率。 该信息使发射机能够瞄准接收机并优化发射机和接收机之间的声能传输。 能量可用于治疗目的，例如刺激组织或用于诊断目的。
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公开(公告)号：US20080294208A1
公开(公告)日：2008-11-27
申请号：US11752775
申请日：2007-05-23
申请人： N. PARKER WILLIS , Axel F. Brisken , Mark W. Cowan , Michael Pare , Robert Fowler , James Brennan
发明人： N. PARKER WILLIS , Axel F. Brisken , Mark W. Cowan , Michael Pare , Robert Fowler , James Brennan
IPC分类号： A61N1/04
CPC分类号： A61N1/3787 , A61N1/37217 , A61N1/37235 , A61N1/3756
摘要： Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
摘要翻译： 公开了用于优化可植入装置中的声能传输的方法和系统。 传感器元件将声学定位器信号传送到接收器组件，并且接收器用位置信号进行响应。 位置信号可以显示与接收机的位置有关的信息和由接收机接收的所发送的声波的效率。 该信息使发射机能够瞄准接收机并优化发射机和接收机之间的声能传输。 能量可用于治疗目的，例如刺激组织或用于诊断目的。
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3.发明授权公开(公告)号：US07953493B2
公开(公告)日：2011-05-31
申请号：US12340395
申请日：2008-12-19
IPC分类号： A61N1/00
CPC分类号： A61N1/378 , A61N1/37217 , A61N1/37288
摘要： A wireless cardiac stimulation device comprising an implantable transmitter module housing a transmitter and a separately implantable battery module housing a battery for powering the transmitter and other device electronics via a subcutaneously routable electrical cable connecting the module is disclosed. The transmitter module contains a transmitter enclosure which comprises one or more ultrasound transducers. Having separate transmitter and battery modules allows implantation of the transmitter module closer to the target receiver implanted in tissue. A discrete battery module also enables easy replacement of the battery without disturbing the transmitter, which is highly desirable.
摘要翻译： 公开了一种无线心脏刺激装置，其包括容纳发射器的可植入发射器模块和容纳用于通过连接所述模块的皮下可路由电缆为所述发射器和其它装置电子设备供电的单独可植入电池模块。 发射机模块包含一个包含一个或多个超声换能器的发射机外壳。 具有单独的发射器和电池模块允许植入发射器模块更靠近植入组织中的目标接收器。 分立的电池模块还能够容易地更换电池而不干扰发射器，这是非常需要的。
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4.发明申请公开(公告)号：US20090264965A1
公开(公告)日：2009-10-22
申请号：US12340395
申请日：2008-12-19
IPC分类号： A61N1/378
CPC分类号： A61N1/378 , A61N1/37217 , A61N1/37288
摘要： A wireless cardiac stimulation device comprising an implantable transmitter module housing a transmitter and a separately implantable battery module housing a battery for powering the transmitter and other device electronics via a subcutaneously routable electrical cable connecting the module is disclosed. The transmitter module contains a transmitter enclosure which comprises one or more ultrasound transducers. Having separate transmitter and battery modules allows implantation of the transmitter module closer to the target receiver implanted in tissue. A discrete battery module also enables easy replacement of the battery without disturbing the transmitter, which is highly desirable.
摘要翻译： 公开了一种无线心脏刺激装置，其包括容纳发射器的可植入发射器模块和容纳用于通过连接所述模块的皮下可路由电缆为所述发射器和其它装置电子设备供电的单独可植入电池模块。 发射机模块包含一个包含一个或多个超声换能器的发射机外壳。 具有单独的发射器和电池模块允许植入发射器模块更靠近植入组织中的目标接收器。 分立的电池模块还能够容易地更换电池而不干扰发射器，这是非常需要的。
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公开(公告)号：US08494643B2
公开(公告)日：2013-07-23
申请号：US13008433
申请日：2011-01-18
IPC分类号： A61N1/08
CPC分类号： A61N1/36071 , A61N1/08 , A61N1/37217
摘要： Systems and methods are disclosed to stimulate nerves to treat medical conditions such as pain, and other conditions, such as, CHF, obesity, incontinence, etc., that could be controlled by the stimulation of the vagal nerves. The invention uses electrical stimulation of the nerve, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined nerve site. The vibrational energy is generated by a controller-transmitter, which could be implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on or around the nerve that needs to be stimulated. The implantable receiver-stimulator stimulates different nerves and regions of a nerve to provide therapeutic benefit.
摘要翻译： 公开了系统和方法以刺激神经来治疗可以通过迷走神经的刺激来控制的医学状况，例如疼痛和其它病症，例如CHF，肥胖症，失禁等。 本发明使用神经的电刺激，其中来自源的振动能量被植入的装置接收并转换成电能，并且转换的电能被植入的电极用于刺激预定的神经部位。 振动能量由控制器 - 发射器产生，其可被植入或位于外部。 接收器刺激器接收振动能，其可以位于需要被刺激的神经上或周围的各个区域中。 可植入接收器刺激器刺激神经的不同神经和区域以提供治疗益处。
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公开(公告)号：US20110166621A1
公开(公告)日：2011-07-07
申请号：US13007419
申请日：2011-01-14
IPC分类号： A61N1/36
CPC分类号： A61N1/37217 , A61N1/36071 , A61N1/37288 , A61N1/3756
摘要： Systems and methods are disclosed to stimulate spine tissue to treat medical conditions such as pain and spinal injury. The invention uses electrical stimulation of the spine, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined brain site. The vibrational energy is generated by a controller-transmitter, which could be located either externally or implanted. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on around the spine. The implantable receiver-stimulator stimulates different locations in the spine region to provide therapeutic benefit.
摘要翻译： 公开了系统和方法来刺激脊柱组织来治疗诸如疼痛和脊柱损伤的医学病症。 本发明使用脊柱的电刺激，其中来自源的振动能量被植入装置接收并转换成电能，并且所转换的电能被植入电极用于刺激预定的脑部位。 振动能量由控制器 - 发射器产生，其可以位于外部或植入。 振动能量由接收器刺激器接收，其可以位于脊柱周围的各个区域中。 可植入接收器刺激器刺激脊柱区域中的不同位置以提供治疗益处。
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公开(公告)号：US20110118810A1
公开(公告)日：2011-05-19
申请号：US13008433
申请日：2011-01-18
IPC分类号： A61N1/08
CPC分类号： A61N1/36071 , A61N1/08 , A61N1/37217
摘要： Systems and methods are disclosed to stimulate nerves to treat medical conditions such as pain, and other conditions, such as, CHF, obesity, incontinence, etc., that could be controlled by the stimulation of the vagal nerves. The invention uses electrical stimulation of the nerve, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined nerve site. The vibrational energy is generated by a controller-transmitter, which could be implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on or around the nerve that needs to be stimulated. The implantable receiver-stimulator stimulates different nerves and regions of a nerve to provide therapeutic benefit.
摘要翻译： 公开了系统和方法以刺激神经来治疗可以通过迷走神经的刺激来控制的医学状况，例如疼痛和其它病症，例如CHF，肥胖症，失禁等。 本发明使用神经的电刺激，其中来自源的振动能量被植入的装置接收并转换成电能，并且转换的电能被植入的电极用于刺激预定的神经部位。 振动能量由控制器 - 发射器产生，其可被植入或位于外部。 接收器刺激器接收振动能，其可以位于需要被刺激的神经上或周围的各个区域中。 可植入接收器刺激器刺激神经的不同神经和区域以提供治疗益处。
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公开(公告)号：US07894910B2
公开(公告)日：2011-02-22
申请号：US11764611
申请日：2007-06-18
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61N1/0541 , A61N1/37217 , A61N1/3756
摘要： Systems and methods are disclosed to enable hearing in the deaf by stimulating sites in the cochlea. The invention uses electrical stimulation in the cochlea, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the cochlear nerve. The vibrational energy is generated by a controller-transmitter, which could be located either externally or implanted. The vibrational energy is received by a receiver-stimulator, which contains multiple electrodes to stimulate along selected sites in the cochlea.
摘要翻译： 公开了系统和方法，以通过刺激耳蜗中的部位来在聋人中进行听觉。 本发明在耳蜗中使用电刺激，其中来自源的振动能量被注入的装置接收并转换成电能，并且转换的电能被注入的电极用于刺激耳蜗神经。 振动能量由控制器 - 发射器产生，其可以位于外部或植入。 接收器刺激器接收振动能量，该接收器刺激器包含多个电极以沿着耳蜗中的选定部位刺激。
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公开(公告)号：US07894907B2
公开(公告)日：2011-02-22
申请号：US11764592
申请日：2007-06-18
IPC分类号： A61N1/08
CPC分类号： A61N1/36071 , A61N1/08 , A61N1/37217
摘要： Systems and methods are disclosed to stimulate nerves to treat medical conditions such as pain, and other conditions, such as, CHF, obesity, incontinence, etc., that could be controlled by the stimulation of the vagal nerves. The invention uses electrical stimulation of the nerve, where vibrational energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined nerve site. The vibrational energy is generated by a controller-transmitter, which could be implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located in the various regions on or around the nerve that needs to be stimulated. The implantable receiver-stimulator stimulates different nerves and regions of a nerve to provide therapeutic benefit.
摘要翻译： 公开了系统和方法以刺激神经来治疗可以通过迷走神经的刺激来控制的医学状况，例如疼痛和其它病症，例如CHF，肥胖症，失禁等。 本发明使用神经的电刺激，其中来自源的振动能量被植入的装置接收并转换成电能，并且转换的电能被植入的电极用于刺激预定的神经部位。 振动能量由控制器 - 发射器产生，其可被植入或位于外部。 接收器刺激器接收振动能，其可以位于需要被刺激的神经上或周围的各个区域中。 可植入接收器刺激器刺激神经的不同神经和区域以提供治疗益处。
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公开(公告)号：US06524271B2
公开(公告)日：2003-02-25
申请号：US09898306
申请日：2001-07-02
申请人： Axel F. Brisken , John R. McKenzie , Robert F. Zuk , Menahem Nassi , Mark W. Cowan , Paul D. Corl
发明人： Axel F. Brisken , John R. McKenzie , Robert F. Zuk , Menahem Nassi , Mark W. Cowan , Paul D. Corl
IPC分类号： A61B1720
CPC分类号： A61B17/2202 , A61B2017/22051 , A61N7/022 , A61N2007/0078
摘要： A method of treating a target region in a body lumen, said method comprising: directing a uniform dose of ultrasonic energy from an interior of the lumen radially outward over a treatment length of the lumen, wherein the dosage of ultrasonic energy received at any one point along the length varies by no more than plus or minus 6 decibels from that received at any other point along the length.
摘要翻译： 一种治疗体腔内的靶区域的方法，所述方法包括：在内腔的治疗长度上径向向外引导来自内腔内部的均匀剂量的超声波能量，其中在任何一点接收的超声能量的剂量 沿着长度变化不大于从沿着长度的任何其他点接收的加/减6分贝。
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