公开(公告)号：US20240057626A1

公开(公告)日：2024-02-22

申请号：US18259286

申请日：2021-12-31

Applicant: N.V. Nutricia

Inventor： Cameron Marshall ,  Tuan Nguyen ,  Ana Ospina Martinez

IPC: A23C9/144 ,  A23C9/142 ,  A23L33/00 ,  A23L33/125 ,  B01D61/14 ,  B01D61/02 ,  B01D61/58 ,  B01D69/02 ,  B01D61/42 ,  A61K31/7016 ,  C13K5/00

CPC classification number: A23C9/144 ,  A23C9/1422 ,  A23L33/40 ,  A23L33/125 ,  B01D61/145 ,  B01D61/027 ,  B01D61/58 ,  B01D69/02 ,  B01D61/422 ,  A61K31/7016 ,  C13K5/00 ,  A23C2210/202 ,  A23C2210/206 ,  B01D2311/06 ,  B01D2325/20 ,  B01D2311/08

Abstract: The present invention provides a process of producing a lactose concentrate, said process comprising the step of subjecting a partially demineralised aqueous lactose isolate to electrodialysis to produce a biotin-reduced lactose isolate containing at least 90% lactose by weight of dry matter and less than 2 mg ash per gram of lactose, and containing:



0.02-1.5 mg sodium per gram of lactose;
0.02-2 mg potassium per gram of lactose;
0.05-1.5 mg chloride per gram of lactose;
0.01-0.25 μg biotin per gram of lactose.




The present invention also relates to a demineralised lactose concentrate having a reduced biotin content that can be produced by the aforementioned process. The invention further relates to an oligosaccharide-enriched biotin-reduced fraction that is obtained when lactose is separated before or after the electrodialysis step.