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公开(公告)号:US20090104209A1
公开(公告)日:2009-04-23
申请号:US12234027
申请日:2008-09-19
申请人: NABIL G. SEIDAH , PATRICK LABONTE
发明人: NABIL G. SEIDAH , PATRICK LABONTE
IPC分类号: A61K39/395 , C12N5/00 , A61K31/7052 , A61K38/16 , A61P31/12 , C12Q1/02 , A61K38/02 , C12Q1/70
CPC分类号: G01N33/569 , C07K14/70596 , C12N9/6408 , G01N2333/96411 , G01N2500/00 , G01N2800/50
摘要: A method for treating and/or preventing a proprotein convertase subtilisin/kexin type 9 preproprotein (PCSK9)-susceptible viral infection comprising increasing a PCSK9 activity and/or expression in a biological system infected by the virus, whereby the increased PCSK9 activity and/or expression treats and/or prevents the viral infection in the biological system. Methods of classifying subjects, methods of screening and kits therefore.
摘要翻译: 用于治疗和/或预防前体蛋白转化酶枯草杆菌蛋白酶/ kexin 9型前蛋白(PCSK9) - 易感性病毒感染的方法,包括增加感染病毒的生物系统中的PCSK9活性和/或表达,由此增加的PCSK9活性和/或 表达治疗和/或预防生物系统中的病毒感染。 因此分类科目的方法,筛选方法和试剂盒。