公开(公告)号：US10815252B2

公开(公告)日：2020-10-27

申请号：US16487845

申请日：2018-02-13

Applicant: NANJING FORESTRY UNIVERSITY

Inventor： Li Xu ,  Shilong Yang ,  Zhong Li

IPC: A61P35/00 ,  C07F1/00

Abstract: A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula: wherein, X is NO3− or Cl−. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.