公开(公告)号：US12083186B2

公开(公告)日：2024-09-10

申请号：US17344543

申请日：2021-06-10

申请人： NaNotics, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K9/51 ,  A61K47/62

CPC分类号： A61K47/6929 ,  A61K9/5115 ,  A61K9/5153 ,  A61K47/62 ,  A61K47/6937

摘要： The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US20240269319A1

公开(公告)日：2024-08-15

申请号：US18633021

申请日：2024-04-11

申请人： NaNotics, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K9/51 ,  A61K47/62

CPC分类号： A61K47/6929 ,  A61K9/5115 ,  A61K9/5153 ,  A61K47/62 ,  A61K47/6937

摘要： The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US20220133905A1

公开(公告)日：2022-05-05

申请号：US17344543

申请日：2021-06-10

申请人： NaNotics, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K47/62 ,  A61K9/51

摘要： The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US11065345B2

公开(公告)日：2021-07-20

申请号：US16476049

申请日：2018-01-04

申请人： NaNotics, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K47/62 ,  A61K9/51

摘要： The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US20180256747A1

公开(公告)日：2018-09-13

申请号：US15738954

申请日：2016-06-29

申请人： NANOTICS, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K9/14 ,  A61K38/17 ,  A61P35/00 ,  A61P39/00 ,  A61P31/18

CPC分类号： A61K47/6937 ,  A61K9/0019 ,  A61K9/143 ,  A61K9/146 ,  A61K9/5078 ,  A61K9/5115 ,  A61K38/17 ,  A61K38/19 ,  A61K39/395 ,  A61K47/02 ,  A61K47/6923 ,  A61K47/6927 ,  A61P31/18 ,  A61P35/00 ,  A61P39/00 ,  Y02A50/385 ,  Y02A50/409 ,  Y02A50/463 ,  Y02A50/475 ,  Y02A50/48 ,  Y02A50/491

摘要： The disclosure provides, among other things, compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US20200179531A1

公开(公告)日：2020-06-11

申请号：US16476049

申请日：2018-01-04

申请人： NaNotics, LLC

发明人： Louis Hawthorne ,  John Dodgson

IPC分类号： A61K47/69 ,  A61K9/51 ,  A61K47/62

摘要： The disclosure provides, methods for preparing scavenging particles, as well as methods for attaching capture agents to the particles. The disclosure further provides compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

公开(公告)号：US10653790B2

公开(公告)日：2020-05-19

申请号：US15748335

申请日：2016-07-29

申请人： NANOTICS, LLC

发明人： John Dodgson ,  Louis Hawthorne

IPC分类号： A61K47/64 ,  A61K9/00 ,  A61K47/66 ,  A61K47/69 ,  A61K47/54 ,  A61K9/51 ,  A61K9/16

摘要： The disclosure provides, among other things, compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells.

公开(公告)号：US20180214566A1

公开(公告)日：2018-08-02

申请号：US15748335

申请日：2016-07-29

申请人： NANOTICS, LLC

发明人： John Dodgson ,  Louis Hawthorne

IPC分类号： A61K47/64 ,  A61K47/66 ,  A61K47/54 ,  A61K9/51 ,  A61K9/00

CPC分类号： A61K47/642 ,  A61K9/0092 ,  A61K9/1676 ,  A61K9/51 ,  A61K47/557 ,  A61K47/665 ,  A61K47/6923

摘要： The disclosure provides, among other things, compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical compositions thereof. The compositions may comprise a plurality of particles that specifically bind a target, such as a soluble biomolecule or a biomolecule on the surface of a pathogen, to inhibit the target (or pathogen) from interacting with other molecules or cells.